SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ift'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 2ift PUTATIVE METHYLASE
HI0767
(Haemophilus
influenzae) 		5 / 12 PHE A  61
GLY A  63
ASP A  85
PRO A 134
LEU A 139
 None
 0.97A 2hmyB-2iftA:
9.1		 2hmyB-2iftA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2ift PUTATIVE METHYLASE
HI0767
(Haemophilus
influenzae) 		5 / 12 ASP A  59
GLY A  63
LEU A  67
ASP A  85
LEU A 139
 None
 0.88A 2nxeA-2iftA:
13.5		 2nxeA-2iftA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 2ift PUTATIVE METHYLASE
HI0767
(Haemophilus
influenzae) 		5 / 12 PHE A  61
GLY A  63
LEU A  67
PRO A 134
LEU A 139
 None
 0.89A 3av6A-2iftA:
8.0		 3av6A-2iftA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2ift PUTATIVE METHYLASE
HI0767
(Haemophilus
influenzae) 		5 / 12 ASP A  59
LEU A  58
GLY A  60
LEU A  67
LEU A 147
 None
 1.00A 3cjtC-2iftA:
14.9		 3cjtC-2iftA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2ift PUTATIVE METHYLASE
HI0767
(Haemophilus
influenzae) 		5 / 12 GLY A  63
SER A  64
LEU A  67
ASP A  85
LEU A 139
 None
 0.93A 3cjtG-2iftA:
14.9		 3cjtG-2iftA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2ift PUTATIVE METHYLASE
HI0767
(Haemophilus
influenzae) 		5 / 12 SER A  64
LEU A  67
ASP A  85
SER A 112
LEU A 139
 None
 1.14A 3cjtK-2iftA:
14.9		 3cjtK-2iftA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2ift PUTATIVE METHYLASE
HI0767
(Haemophilus
influenzae) 		5 / 12 GLY A  63
SER A  64
LEU A  67
ASP A  85
LEU A 139
 None
 0.92A 3cjtO-2iftA:
14.9		 3cjtO-2iftA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 2ift PUTATIVE METHYLASE
HI0767
(Haemophilus
influenzae) 		4 / 8 ILE A 144
LEU A 153
THR A 163
VAL A 129
 None
 0.78A 3dcjB-2iftA:
3.1		 3dcjB-2iftA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2ift PUTATIVE METHYLASE
HI0767
(Haemophilus
influenzae) 		4 / 8 LEU A  96
ILE A 109
PHE A  81
GLY A  68
 None
 0.85A 4hb6A-2iftA:
undetectable		 4hb6A-2iftA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2ift PUTATIVE METHYLASE
HI0767
(Haemophilus
influenzae) 		5 / 12 ASP A 132
PHE A  61
GLY A  63
SER A  64
GLU A  83
 None
 1.26A 5hfjE-2iftA:
5.3		 5hfjE-2iftA:
21.07