SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ig2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 2ig2 IGG1-LAMBDA KOL FAB
(HEAVY CHAIN)
(Homo
sapiens) 		4 / 8 GLN H   6
VAL H 114
GLY H   8
GLY H   9
 None
 0.74A 1ekjE-2ig2H:
undetectable
1ekjF-2ig2H:
undetectable		 1ekjE-2ig2H:
19.61
1ekjF-2ig2H:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2ig2 IGG1-LAMBDA KOL FAB
(HEAVY CHAIN)
(Homo
sapiens) 		4 / 8 GLY H 195
LEU H 194
VAL H 187
LEU H 143
 None
 0.83A 6czmD-2ig2H:
2.1
6czmF-2ig2H:
undetectable		 6czmD-2ig2H:
21.80
6czmF-2ig2H:
21.80