SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ig6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RKY_A_CUA801_0 (LYSYL OXIDASE)	2ig6	NIMC/NIMA FAMILY PROTEIN (Clostridium acetobutylicum)	3 / 3	HIS A -8 HIS A -7 HIS A -10	None SO4 A 132 (-3.6A) SO4 A 132 (-3.6A)	0.69A	1rkyA-2ig6A: undetectable	1rkyA-2ig6A: 11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z95_A_198A501_2 (ANDROGEN RECEPTOR)	2ig6	NIMC/NIMA FAMILY PROTEIN (Clostridium acetobutylicum)	4 / 6	LEU A 73 MET A 53 LEU A 16 ILE A 71	None	0.91A	1z95A-2ig6A: undetectable	1z95A-2ig6A: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YV5_B_SVRB207_2 (BASIC PHOSPHOLIPASE A2 HOMOLOG 2)	2ig6	NIMC/NIMA FAMILY PROTEIN (Clostridium acetobutylicum)	4 / 7	TYR A 35 TYR A 40 LEU A 39 PHE A 112	None	1.16A	4yv5B-2ig6A: undetectable	4yv5B-2ig6A: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NKN_A_LOCA201_2 (NEUTROPHIL GELATINASE-ASSOCIATE D LIPOCALIN)	2ig6	NIMC/NIMA FAMILY PROTEIN (Clostridium acetobutylicum)	3 / 3	VAL A 109 LYS A 38 MET A 1	None	0.93A	5nknA-2ig6A: undetectable	5nknA-2ig6A: 19.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RKY_A_CUA801_0","LYSYL OXIDASE","2ig6","NIMC\/NIMA FAMILY PROTEIN","Clostridium acetobutylicum",3,"HIS A  -8;HIS A  -7;HIS A -10","None;SO4 A 132 (-3.6A);SO4 A 132 (-3.6A)","0.69A","1rkyA-2ig6A:undetectable","1rkyA-2ig6A:11.14"],["1Z95_A_198A501_2","ANDROGEN RECEPTOR","2ig6","NIMC\/NIMA FAMILY PROTEIN","Clostridium acetobutylicum",4,"LEU A  73;MET A  53;LEU A  16;ILE A  71","None","0.91A","1z95A-2ig6A:undetectable","1z95A-2ig6A:19.20"],["4YV5_B_SVRB207_2","BASIC PHOSPHOLIPASE A2 HOMOLOG 2","2ig6","NIMC\/NIMA FAMILY PROTEIN","Clostridium acetobutylicum",4,"TYR A  35;TYR A  40;LEU A  39;PHE A 112","None","1.16A","4yv5B-2ig6A:undetectable","4yv5B-2ig6A:22.86"],["5NKN_A_LOCA201_2","NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN","2ig6","NIMC\/NIMA FAMILY PROTEIN","Clostridium acetobutylicum",3,"VAL A 109;LYS A  38;MET A   1","None","0.93A","5nknA-2ig6A:undetectable","5nknA-2ig6A:19.33"]]