SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ihw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2ihw LIPOAMIDE
ACYLTRANSFERASE
COMPONENT OF
BRANCHED-CHAIN
ALPHA-KETO ACID
DEHYDROGENASE
COMPLEX
(Bos
taurus) 		5 / 12 GLY A 320
LEU A 325
LEU A 316
GLY A 284
ALA A 286
 None
None
None
None
ACT  A 600 ( 4.5A)
 1.07A 2bm9F-2ihwA:
undetectable		 2bm9F-2ihwA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2ihw LIPOAMIDE
ACYLTRANSFERASE
COMPONENT OF
BRANCHED-CHAIN
ALPHA-KETO ACID
DEHYDROGENASE
COMPLEX
(Bos
taurus) 		4 / 8 THR A 336
LEU A 293
LEU A 330
GLY A 284
 None
ACT  A 601 (-4.5A)
None
None
 0.70A 4r3aA-2ihwA:
undetectable		 4r3aA-2ihwA:
23.45