SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ii1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		3 / 3 PHE A 291
LEU A 249
LEU A 263
 None
 0.66A 1mx1E-2ii1A:
undetectable		 1mx1E-2ii1A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		5 / 12 MET A  13
ASN A 154
ILE A  78
ILE A  81
LEU A 155
 None
CA  A 400 (-2.8A)
None
None
None
 1.11A 2bjfA-2ii1A:
undetectable		 2bjfA-2ii1A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		5 / 7 GLY A 135
ALA A 175
ALA A 137
VAL A  65
ILE A  76
 None
 1.15A 3a2qA-2ii1A:
undetectable		 3a2qA-2ii1A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		4 / 5 ALA A 241
LEU A 264
GLY A 268
THR A 223
 None
 0.97A 3dl9A-2ii1A:
undetectable		 3dl9A-2ii1A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		4 / 5 ASN A 144
ALA A 178
LEU A 168
GLY A 152
 None
 0.79A 3dl9A-2ii1A:
undetectable		 3dl9A-2ii1A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		5 / 12 GLY A 180
VAL A  56
ALA A 178
ALA A 137
ASP A  14
 None
 1.07A 3sugA-2ii1A:
undetectable		 3sugA-2ii1A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		4 / 4 PRO A 148
LEU A 155
ILE A 228
ARG A 283
 None
 1.42A 3w1wA-2ii1A:
undetectable		 3w1wA-2ii1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		5 / 10 LEU A 204
ILE A  81
ILE A  76
GLY A 163
PHE A  31
 None
 0.88A 4fakA-2ii1A:
undetectable		 4fakA-2ii1A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		4 / 8 VAL A 202
GLY A 132
VAL A  83
ILE A  81
 None
CA  A 400 ( 4.9A)
None
None
 0.70A 4ll3A-2ii1A:
undetectable		 4ll3A-2ii1A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		4 / 5 ASN A 277
PRO A 148
GLY A 146
ASP A 181
 CA  A 400 ( 4.3A)
None
None
CA  A 401 ( 2.3A)
 0.97A 4n48B-2ii1A:
undetectable		 4n48B-2ii1A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		6 / 12 GLY A 153
PRO A 148
GLY A 149
ASN A 154
ILE A  10
THR A   9
 None
None
None
CA  A 400 (-2.8A)
None
None
 1.37A 4n49A-2ii1A:
undetectable		 4n49A-2ii1A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		5 / 12 THR A 281
GLY A 152
GLY A 149
LEU A 179
THR A  33
 None
 1.04A 4uckB-2ii1A:
undetectable		 4uckB-2ii1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		5 / 10 LEU A 182
GLY A 200
ASP A  80
ILE A 131
PRO A 162
 None
 1.12A 4xj7C-2ii1A:
undetectable
4xj7D-2ii1A:
undetectable		 4xj7C-2ii1A:
26.05
4xj7D-2ii1A:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		4 / 8 VAL A  29
ILE A  76
ALA A 175
LEU A  63
 None
 0.77A 5og9A-2ii1A:
undetectable		 5og9A-2ii1A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 2ii1 ACETAMIDASE
(Bacillus
halodurans) 		4 / 8 VAL A  29
THR A 136
ALA A 175
LEU A  63
 None
 0.76A 5og9A-2ii1A:
undetectable		 5og9A-2ii1A:
21.59