SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ij9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 7 GLY A 200
ALA A 208
ILE A 198
THR A  25
 None
 0.75A 1gtnA-2ij9A:
undetectable
1gtnK-2ij9A:
undetectable		 1gtnA-2ij9A:
17.14
1gtnK-2ij9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 8 THR A  25
GLY A 200
ALA A 208
ILE A 198
 None
 0.79A 1gtnA-2ij9A:
undetectable
1gtnB-2ij9A:
undetectable		 1gtnA-2ij9A:
17.14
1gtnB-2ij9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 8 THR A  25
GLY A 200
ALA A 208
ILE A 198
 None
 0.75A 1gtnE-2ij9A:
undetectable
1gtnF-2ij9A:
undetectable		 1gtnE-2ij9A:
17.14
1gtnF-2ij9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 8 GLY A 200
ALA A 208
ILE A 198
THR A  25
 None
 0.80A 1utdB-2ij9A:
undetectable
1utdC-2ij9A:
undetectable		 1utdB-2ij9A:
17.14
1utdC-2ij9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 8 GLY A 200
ALA A 208
ILE A 198
THR A  25
 None
 0.79A 1utdF-2ij9A:
undetectable
1utdG-2ij9A:
undetectable		 1utdF-2ij9A:
17.14
1utdG-2ij9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 8 GLY A 200
ALA A 208
ILE A 198
THR A  25
 None
 0.77A 1utdI-2ij9A:
undetectable
1utdJ-2ij9A:
undetectable		 1utdI-2ij9A:
17.14
1utdJ-2ij9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 8 GLY A 200
ALA A 208
ILE A 198
THR A  25
 None
 0.78A 1utdJ-2ij9A:
undetectable
1utdK-2ij9A:
undetectable		 1utdJ-2ij9A:
17.14
1utdK-2ij9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  12
GLY A   9
GLY A  40
GLY A 108
ARG A  71
 None
SO4  A 301 (-3.3A)
SO4  A 301 (-3.4A)
None
None
 1.17A 1y4lA-2ij9A:
undetectable		 1y4lA-2ij9A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A   7
VAL A  11
LEU A   5
THR A 136
ALA A 135
 None
 1.05A 2egvA-2ij9A:
4.1		 2egvA-2ij9A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 187
ALA A 120
ILE A 218
LEU A 163
THR A 119
 None
 1.14A 2zzaA-2ij9A:
undetectable		 2zzaA-2ij9A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		5 / 11 ILE A 187
ALA A 120
ILE A 218
LEU A 163
THR A 119
 None
 1.13A 2zzaB-2ij9A:
undetectable		 2zzaB-2ij9A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 6 VAL A 141
LEU A 158
ILE A 218
VAL A 167
 None
 0.88A 4a9kA-2ij9A:
0.0		 4a9kA-2ij9A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		5 / 12 VAL A   3
VAL A 106
ALA A 208
LEU A  12
VAL A  11
 None
 1.25A 4ib4A-2ij9A:
undetectable		 4ib4A-2ij9A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		5 / 11 ILE A 187
ALA A 120
LEU A 163
ILE A 188
THR A 119
 None
 1.17A 4p66A-2ij9A:
undetectable		 4p66A-2ij9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		6 / 12 ILE A 187
ALA A 120
ILE A 218
LEU A 163
ILE A 188
THR A 119
 None
 1.39A 4x5iA-2ij9A:
undetectable		 4x5iA-2ij9A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 5 VAL A 209
ILE A 205
VAL A  29
THR A  25
 None
 0.60A 4xdtA-2ij9A:
undetectable		 4xdtA-2ij9A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 7 ASN A 137
VAL A  11
SER A  10
GLY A  41
 None
None
None
SO4  A 301 (-4.3A)
 0.91A 5fpdA-2ij9A:
undetectable		 5fpdA-2ij9A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 7 ASN A 137
VAL A  11
SER A  10
GLY A  40
 None
None
None
SO4  A 301 (-3.4A)
 0.82A 5fpdB-2ij9A:
undetectable		 5fpdB-2ij9A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		4 / 7 ASN A 137
VAL A  11
SER A  10
GLY A  41
 None
None
None
SO4  A 301 (-4.3A)
 0.92A 5fpdB-2ij9A:
undetectable		 5fpdB-2ij9A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		3 / 3 SER A 143
TYR A 142
TYR A 155
 None
 0.86A 5lakA-2ij9A:
undetectable
5lakI-2ij9A:
undetectable		 5lakA-2ij9A:
21.24
5lakI-2ij9A:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		3 / 3 SER A 143
TYR A 142
TYR A 155
 None
 0.79A 5lakC-2ij9A:
undetectable
5lakJ-2ij9A:
undetectable		 5lakC-2ij9A:
21.24
5lakJ-2ij9A:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		5 / 10 VAL A  39
GLY A  40
GLY A  42
THR A  70
ALA A  74
 None
SO4  A 301 (-3.4A)
None
None
None
 1.04A 5vm8B-2ij9A:
2.8		 5vm8B-2ij9A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 2ij9 URIDYLATE KINASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A   7
GLY A  40
THR A 115
THR A 116
VAL A 197
 None
SO4  A 301 (-3.4A)
None
SO4  A 301 (-3.4A)
None
 1.08A 6emuC-2ij9A:
3.7		 6emuC-2ij9A:
23.08