SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ijc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 2ijc HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ALA A  59
GLU A  64
LEU A  69
LEU A  72
 None
 0.98A 1ereE-2ijcA:
undetectable		 1ereE-2ijcA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 2ijc HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ALA A  59
GLU A  64
LEU A  69
LEU A  72
 None
 0.97A 1ereF-2ijcA:
undetectable		 1ereF-2ijcA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 2ijc HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 135
VAL A  38
THR A  92
 None
 0.85A 3cyxA-2ijcA:
undetectable		 3cyxA-2ijcA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 2ijc HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ILE A  35
TYR A  39
ALA A  28
LEU A  30
 None
 0.83A 3ozwA-2ijcA:
undetectable		 3ozwA-2ijcA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 2ijc HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 ARG A  84
LEU A  34
ALA A 126
ILE A  35
 None
 0.89A 3wsjB-2ijcA:
undetectable		 3wsjB-2ijcA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ijc HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLU A  93
THR A  92
THR A  82
LEU A  72
 None
 1.01A 4pgfA-2ijcA:
undetectable		 4pgfA-2ijcA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 2ijc HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A  31
ILE A 120
ALA A  28
 None
 0.46A 4wnwB-2ijcA:
undetectable		 4wnwB-2ijcA:
13.62