SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ijd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 9 ILE 1  49
VAL 1  16
ILE 1  36
ILE 1  56
ILE 1  47
 None
 0.94A 1hshB-2ijd1:
undetectable		 1hshB-2ijd1:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 ASN 1 484
ASN 1 485
ILE 1 507
GLY 1 390
 None
 0.97A 1oniA-2ijd1:
undetectable
1oniB-2ijd1:
undetectable		 1oniA-2ijd1:
11.49
1oniB-2ijd1:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 ASN 1 484
ASN 1 485
ILE 1 507
GLY 1 390
 None
 0.98A 1oniD-2ijd1:
undetectable
1oniF-2ijd1:
undetectable		 1oniD-2ijd1:
11.49
1oniF-2ijd1:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.08A 1p7lC-2ijd1:
undetectable		 1p7lC-2ijd1:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.08A 1p7lD-2ijd1:
undetectable		 1p7lD-2ijd1:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.09A 1rg9A-2ijd1:
undetectable		 1rg9A-2ijd1:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.09A 1rg9B-2ijd1:
undetectable		 1rg9B-2ijd1:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.07A 1rg9C-2ijd1:
undetectable		 1rg9C-2ijd1:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.08A 1rg9D-2ijd1:
undetectable		 1rg9D-2ijd1:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 7 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
 None
 1.03A 1rxcC-2ijd1:
undetectable		 1rxcC-2ijd1:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 7 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
 None
 1.00A 1rxcD-2ijd1:
undetectable		 1rxcD-2ijd1:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 7 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
 None
 1.07A 1rxcL-2ijd1:
undetectable		 1rxcL-2ijd1:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 7 TYR 1 509
ASP 1 511
ASP 1 512
LYS 1 542
 None
None
None
SO4  1 648 (-3.2A)
 0.98A 1t03A-2ijd1:
3.6		 1t03A-2ijd1:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 9 LEU 1 377
PHE 1 381
LEU 1 436
LEU 1 432
ALA 1 265
 None
 1.14A 2bxeA-2ijd1:
undetectable		 2bxeA-2ijd1:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.17A 2obvA-2ijd1:
undetectable		 2obvA-2ijd1:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 VAL 1 116
TYR 1 138
VAL 1 104
TYR 1 109
 None
 1.16A 2y05A-2ijd1:
undetectable
2y05B-2ijd1:
undetectable		 2y05A-2ijd1:
17.86
2y05B-2ijd1:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 ASN 1 484
SER 1 481
ALA 1 508
ASP 1 512
 None
 1.29A 3aruA-2ijd1:
undetectable		 3aruA-2ijd1:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU 1  77
VAL 1  16
VAL 1  30
GLY 1  29
ILE 1  75
 None
 1.22A 3bf1A-2ijd1:
undetectable
3bf1B-2ijd1:
undetectable		 3bf1A-2ijd1:
16.69
3bf1B-2ijd1:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 GLY 1 354
THR 1 349
ARG 1 346
ALA 1 224
GLU 1 344
 None
None
SO4  1 647 ( 3.8A)
None
None
 1.03A 3g8bB-2ijd1:
undetectable		 3g8bB-2ijd1:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 PHE 1 413
SER 1 516
THR 1 495
LEU 1 504
THR 1 548
 None
 1.18A 3hj3C-2ijd1:
undetectable		 3hj3C-2ijd1:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		3 / 3 ALA 1 133
ARG 1 134
LYS 1 175
 None
SO4  1 646 (-2.6A)
SO4  1 646 ( 3.7A)
 0.91A 3kp3B-2ijd1:
undetectable		 3kp3B-2ijd1:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
 None
 1.01A 3kvvA-2ijd1:
undetectable		 3kvvA-2ijd1:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
 None
 1.00A 3kvvB-2ijd1:
undetectable		 3kvvB-2ijd1:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
 None
 0.96A 3kvvC-2ijd1:
undetectable		 3kvvC-2ijd1:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
 None
 0.98A 3kvvD-2ijd1:
undetectable		 3kvvD-2ijd1:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
 None
 0.98A 3kvvE-2ijd1:
undetectable		 3kvvE-2ijd1:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
 None
 1.03A 3kvvF-2ijd1:
undetectable		 3kvvF-2ijd1:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 LEU 1 557
PHE 1 556
ILE 1 507
ALA 1 508
 None
 0.80A 3mdrA-2ijd1:
undetectable		 3mdrA-2ijd1:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 9 ILE 1  15
THR 1  20
ARG 1  79
GLU 1  81
GLY 1  51
 None
 1.16A 3nxuB-2ijd1:
undetectable		 3nxuB-2ijd1:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 TYR 1 303
ILE 1 313
SER 1 362
SER 1 363
 None
 1.07A 3pmzD-2ijd1:
undetectable		 3pmzD-2ijd1:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_D_DXCD92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 5 VAL 1 513
GLU 1 579
LYS 1 542
PHE 1 415
 None
None
SO4  1 648 (-3.2A)
None
 1.04A 3rv5C-2ijd1:
0.4
3rv5D-2ijd1:
0.4		 3rv5C-2ijd1:
9.31
3rv5D-2ijd1:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 9 ILE 1  49
VAL 1  16
ILE 1  36
ILE 1  56
ILE 1  47
 None
 1.00A 3s43A-2ijd1:
2.4		 3s43A-2ijd1:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		6 / 9 ASP 1 421
ASN 1 480
TYR 1 509
GLY 1 510
ASP 1 511
ASP 1 512
 None
 0.60A 3sfuA-2ijd1:
30.9		 3sfuA-2ijd1:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 9 THR 1 476
TYR 1 509
GLY 1 510
ASP 1 511
ASP 1 512
 None
 0.54A 3sfuA-2ijd1:
30.9		 3sfuA-2ijd1:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		7 / 9 ASP 1 421
ASN 1 480
TYR 1 509
GLY 1 510
ASP 1 511
ASP 1 512
LEU 1 557
 None
 0.59A 3sfuB-2ijd1:
31.1		 3sfuB-2ijd1:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		6 / 11 LYS 1 342
ARG 1 357
ASP 1 421
ASN 1 480
GLY 1 510
ASP 1 511
 None
 0.87A 3sfuC-2ijd1:
31.0		 3sfuC-2ijd1:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 11 LYS 1 342
ASP 1 421
THR 1 476
GLY 1 510
ASP 1 511
 None
 0.89A 3sfuC-2ijd1:
31.0		 3sfuC-2ijd1:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 MET 1 324
LEU 1 327
PRO 1 302
TYR 1 331
 None
 1.44A 3vkxA-2ijd1:
undetectable		 3vkxA-2ijd1:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU 1 451
LEU 1 436
ALA 1 380
ALA 1 379
TYR 1 378
 None
 1.01A 3vw7A-2ijd1:
undetectable		 3vw7A-2ijd1:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 ALA 1 224
THR 1 235
ILE 1 241
SER 1 243
PHE 1 237
 None
 1.17A 4c49A-2ijd1:
undetectable		 4c49A-2ijd1:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 9 GLY 1 300
VAL 1 304
MET 1 306
SER 1 363
VAL 1 338
 None
 1.37A 4da6A-2ijd1:
undetectable		 4da6A-2ijd1:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 11 GLY 1 300
VAL 1 304
MET 1 306
SER 1 363
VAL 1 338
 None
 1.27A 4danA-2ijd1:
undetectable		 4danA-2ijd1:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 GLY 1 300
VAL 1 304
MET 1 306
SER 1 363
VAL 1 338
 None
 1.29A 4danA-2ijd1:
undetectable
4danB-2ijd1:
undetectable		 4danA-2ijd1:
17.31
4danB-2ijd1:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 7 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
 None
 1.01A 4e1vB-2ijd1:
undetectable		 4e1vB-2ijd1:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 GLY 1 390
GLN 1 267
ARG 1 489
ILE 1 507
 None
 1.05A 4e1vF-2ijd1:
undetectable		 4e1vF-2ijd1:
17.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		3 / 3 VAL 1 304
GLY 1 307
LYS 1 309
 None
 0.74A 4k50A-2ijd1:
51.2		 4k50A-2ijd1:
41.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		3 / 3 HIS 1 382
GLY 1 475
ILE 1 478
 None
 0.28A 4k50A-2ijd1:
51.2		 4k50A-2ijd1:
41.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		3 / 3 VAL 1 304
GLY 1 307
LYS 1 309
 None
 0.65A 4k50E-2ijd1:
51.3		 4k50E-2ijd1:
41.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		3 / 3 HIS 1 382
GLY 1 475
ILE 1 478
 None
 0.28A 4k50I-2ijd1:
51.2		 4k50I-2ijd1:
41.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 5 LEU 1 630
PRO 1 631
LEU 1 616
ILE 1 619
 None
SO4  1 649 (-3.4A)
None
None
 0.99A 4klrA-2ijd1:
undetectable		 4klrA-2ijd1:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU 1  28
THR 1 152
GLY 1 155
HIS 1  89
MET 1  10
 None
 1.48A 4lvcC-2ijd1:
undetectable		 4lvcC-2ijd1:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 7 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.16A 4odjA-2ijd1:
undetectable		 4odjA-2ijd1:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		3 / 3 PRO 1 110
MET 1 112
TYR 1 109
 None
 0.99A 4qa2B-2ijd1:
undetectable		 4qa2B-2ijd1:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 7 ALA 1 508
ILE 1 404
LEU 1 557
PHE 1 556
 None
 1.06A 4uymA-2ijd1:
undetectable		 4uymA-2ijd1:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 GLY 1 354
GLN 1 353
SER 1 356
SER 1 347
 None
None
None
SO4  1 648 (-3.0A)
 1.04A 4wrzA-2ijd1:
undetectable		 4wrzA-2ijd1:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 GLY 1 354
GLN 1 353
SER 1 356
SER 1 347
 None
None
None
SO4  1 648 (-3.0A)
 0.86A 4ws1A-2ijd1:
undetectable		 4ws1A-2ijd1:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.12A 5a1iA-2ijd1:
undetectable		 5a1iA-2ijd1:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 7 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.12A 5a1iA-2ijd1:
undetectable		 5a1iA-2ijd1:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 6 LYS 1 244
TYR 1 245
GLY 1 472
ASP 1 294
 None
 1.15A 5emlA-2ijd1:
undetectable		 5emlA-2ijd1:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
GLY 1 608
VAL 1 574
HIS 1 572
 None
 0.74A 5f8yA-2ijd1:
undetectable		 5f8yA-2ijd1:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
GLY 1 608
VAL 1 574
HIS 1 572
 None
 0.74A 5f8yB-2ijd1:
undetectable		 5f8yB-2ijd1:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU 1  28
THR 1 152
GLY 1 155
HIS 1  89
MET 1  10
 None
 1.50A 5hm8A-2ijd1:
undetectable		 5hm8A-2ijd1:
23.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU 1  28
THR 1 152
GLY 1 155
HIS 1  89
MET 1  10
 None
 1.49A 5hm8B-2ijd1:
undetectable		 5hm8B-2ijd1:
23.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU 1  28
THR 1 152
GLY 1 155
HIS 1  89
MET 1  10
 None
 1.50A 5hm8E-2ijd1:
undetectable		 5hm8E-2ijd1:
23.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU 1  28
THR 1 152
GLY 1 155
HIS 1  89
MET 1  10
 None
 1.49A 5hm8F-2ijd1:
undetectable		 5hm8F-2ijd1:
23.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU 1  28
THR 1 152
GLY 1 155
HIS 1  89
MET 1  10
 None
 1.49A 5hm8H-2ijd1:
undetectable		 5hm8H-2ijd1:
23.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.12A 5t8sB-2ijd1:
undetectable		 5t8sB-2ijd1:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 7 LEU 1 628
PHE 1 217
ALA 1 212
THR 1 587
 None
 0.88A 6a7jA-2ijd1:
undetectable		 6a7jA-2ijd1:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 11 VAL 1 150
LEU 1 174
ALA 1   7
VAL 1 119
TYR 1 138
 None
 1.21A 6dryA-2ijd1:
undetectable		 6dryA-2ijd1:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.21A 6fbnB-2ijd1:
undetectable		 6fbnB-2ijd1:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.14A 6fboA-2ijd1:
undetectable		 6fboA-2ijd1:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 8 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.11A 6fcdA-2ijd1:
undetectable		 6fcdA-2ijd1:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 7 HIS 1 606
PRO 1 573
PHE 1 644
ASP 1 398
 None
 1.13A 6g6rA-2ijd1:
undetectable		 6g6rA-2ijd1:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		5 / 12 LEU 1  28
THR 1 152
GLY 1 155
HIS 1  89
MET 1  10
 None
 1.49A 6gbnA-2ijd1:
undetectable		 6gbnA-2ijd1:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 5 LEU 1 102
ILE 1  49
MET 1 160
GLY 1 159
 None
 1.03A 6hd6A-2ijd1:
undetectable		 6hd6A-2ijd1:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 2ijd PICORNAIN 3C,
RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
C) 		4 / 5 GLY 1 332
LEU 1 328
SER 1 363
TYR 1 303
 None
 1.20A 6ji6A-2ijd1:
undetectable		 6ji6A-2ijd1:
16.22