SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ijl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 2ijl MOLYBDENUM-BINDING
TRANSCRIPTIONAL
REPRESSOR
(Agrobacterium
fabrum) 		4 / 5 LEU A  32
LEU A  29
LEU A  22
MET A  46
 None
 1.07A 2oaxF-2ijlA:
undetectable		 2oaxF-2ijlA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 2ijl MOLYBDENUM-BINDING
TRANSCRIPTIONAL
REPRESSOR
(Agrobacterium
fabrum) 		5 / 11 SER A  40
SER A  38
ALA A  42
GLY A  43
ALA A  53
 None
 1.37A 2xh9A-2ijlA:
undetectable		 2xh9A-2ijlA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1437_1
(ORF12)		 2ijl MOLYBDENUM-BINDING
TRANSCRIPTIONAL
REPRESSOR
(Agrobacterium
fabrum) 		5 / 10 SER A  40
SER A  38
ALA A  42
GLY A  43
ALA A  53
 None
 1.36A 2xh9B-2ijlA:
undetectable		 2xh9B-2ijlA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2ijl MOLYBDENUM-BINDING
TRANSCRIPTIONAL
REPRESSOR
(Agrobacterium
fabrum) 		5 / 12 ARG A  44
LEU A  29
GLY A  25
ALA A  45
ALA A  42
 None
None
SO4  A 203 (-3.2A)
None
None
 1.06A 3sufA-2ijlA:
undetectable		 3sufA-2ijlA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 2ijl MOLYBDENUM-BINDING
TRANSCRIPTIONAL
REPRESSOR
(Agrobacterium
fabrum) 		4 / 8 ILE A  69
ILE A  33
ALA A  42
TRP A  54
 None
 0.97A 4ou1A-2ijlA:
undetectable		 4ou1A-2ijlA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2ijl MOLYBDENUM-BINDING
TRANSCRIPTIONAL
REPRESSOR
(Agrobacterium
fabrum) 		3 / 3 LEU A  12
GLY A  23
PHE A  64
 None
SO4  A 203 (-3.2A)
None
 0.66A 6exiC-2ijlA:
undetectable		 6exiC-2ijlA:
18.71