SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ijr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 2ijr HYPOTHETICAL PROTEIN
API92
(Yersinia
pseudotuberculos
is) 		3 / 3 MET A 238
LEU A 241
SER A 242
 None
 0.45A 1ee2A-2ijrA:
undetectable		 1ee2A-2ijrA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2ijr HYPOTHETICAL PROTEIN
API92
(Yersinia
pseudotuberculos
is) 		3 / 3 ILE A  37
ILE A  99
LEU A  66
 None
 0.56A 2prgA-2ijrA:
undetectable		 2prgA-2ijrA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 2ijr HYPOTHETICAL PROTEIN
API92
(Yersinia
pseudotuberculos
is) 		4 / 8 ILE A 111
LEU A  43
PHE A  81
GLY A  47
 None
 0.98A 2vdbA-2ijrA:
undetectable		 2vdbA-2ijrA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 2ijr HYPOTHETICAL PROTEIN
API92
(Yersinia
pseudotuberculos
is) 		4 / 7 TYR A  60
ASN A 182
LEU A 188
SER A 192
 None
 1.23A 3lslA-2ijrA:
undetectable
3lslD-2ijrA:
undetectable		 3lslA-2ijrA:
22.12
3lslD-2ijrA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 2ijr HYPOTHETICAL PROTEIN
API92
(Yersinia
pseudotuberculos
is) 		4 / 7 SER A 192
TYR A  60
ASN A 182
LEU A 188
 None
 1.21A 3lslA-2ijrA:
undetectable
3lslD-2ijrA:
undetectable		 3lslA-2ijrA:
22.12
3lslD-2ijrA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 2ijr HYPOTHETICAL PROTEIN
API92
(Yersinia
pseudotuberculos
is) 		5 / 12 GLY A 269
ALA A 243
ASP A 246
PRO A 174
ILE A 173
 None
 0.97A 3s56A-2ijrA:
undetectable		 3s56A-2ijrA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME
KP18CYS PEPTIDE)		 2ijr HYPOTHETICAL PROTEIN
API92
(Yersinia
pseudotuberculos
is) 		5 / 12 GLN A 134
SER A 185
LEU A 187
VAL A 191
LEU A 177
 None
 1.33A 4k38A-2ijrA:
undetectable
4k38D-2ijrA:
undetectable		 4k38A-2ijrA:
20.97
4k38D-2ijrA:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 2ijr HYPOTHETICAL PROTEIN
API92
(Yersinia
pseudotuberculos
is) 		5 / 12 GLY A  47
GLY A  50
PRO A  54
LEU A  45
LEU A  66
 None
 1.06A 5bw4A-2ijrA:
undetectable		 5bw4A-2ijrA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 2ijr HYPOTHETICAL PROTEIN
API92
(Yersinia
pseudotuberculos
is) 		5 / 12 GLY A  47
GLY A  50
PRO A  54
LEU A  45
LEU A  66
 None
 1.12A 5bw4B-2ijrA:
undetectable		 5bw4B-2ijrA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 2ijr HYPOTHETICAL PROTEIN
API92
(Yersinia
pseudotuberculos
is) 		3 / 3 ASN A 258
TYR A 231
CYH A   5
 None
 0.72A 5lsuB-2ijrA:
undetectable		 5lsuB-2ijrA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 2ijr HYPOTHETICAL PROTEIN
API92
(Yersinia
pseudotuberculos
is) 		5 / 12 LEU A 222
LEU A 224
MET A  21
MET A 169
LEU A 241
 None
 1.17A 5mwyA-2ijrA:
undetectable		 5mwyA-2ijrA:
18.82