SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2il1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 2il1 RAB12
(Homo
sapiens) 		4 / 8 GLY A 250
GLU A 280
ALA A 281
ILE A 292
 None
 0.56A 2dtjA-2il1A:
undetectable
2dtjB-2il1A:
undetectable		 2dtjA-2il1A:
21.23
2dtjB-2il1A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 2il1 RAB12
(Homo
sapiens) 		4 / 8 ILE A 144
SER A 146
GLY A 145
ASN A 201
 None
 0.96A 3lslA-2il1A:
undetectable
3lslD-2il1A:
undetectable		 3lslA-2il1A:
22.27
3lslD-2il1A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 2il1 RAB12
(Homo
sapiens) 		4 / 8 ASN A 251
ALA A 281
SER A 282
LEU A 154
 GDP  A 401 (-3.2A)
None
GDP  A 401 (-3.5A)
None
 1.15A 4ijiF-2il1A:
undetectable		 4ijiF-2il1A:
20.00