SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2il5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 2il5 HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 7 MET A  89
TYR A 121
ASP A 101
TYR A  60
 None
 1.47A 2bytA-2il5A:
undetectable		 2bytA-2il5A:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 2il5 HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 7 MET A  89
TYR A 121
ASP A 101
TYR A  60
 None
 1.48A 2bytD-2il5A:
undetectable		 2bytD-2il5A:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 2il5 HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 8 TYR A  78
VAL A  54
TRP A  30
ILE A  50
 None
 0.94A 2gssA-2il5A:
undetectable		 2gssA-2il5A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 2il5 HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 8 TYR A  78
VAL A  54
TRP A  30
ILE A  50
 None
 0.94A 2gssB-2il5A:
undetectable		 2gssB-2il5A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 2il5 HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 8 MET A  89
TYR A 121
ASP A 101
TYR A  60
 None
 1.35A 2v0gA-2il5A:
undetectable		 2v0gA-2il5A:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 2il5 HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 8 TYR A  78
VAL A  54
TRP A  30
ILE A  50
 None
 0.96A 3hjoA-2il5A:
undetectable		 3hjoA-2il5A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2il5 HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 4 ASP A  53
GLY A  57
LYS A  55
GLU A  56
 None
 1.46A 3hznD-2il5A:
undetectable		 3hznD-2il5A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 2il5 HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 8 TYR A  78
VAL A  54
TRP A  30
ILE A  50
 None
 0.92A 3n9jA-2il5A:
undetectable		 3n9jA-2il5A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2il5 HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 7 ILE A  91
ARG A  61
ILE A  62
MET A  41
 None
 0.96A 4xumA-2il5A:
undetectable		 4xumA-2il5A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 2il5 HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		4 / 6 TYR A  78
THR A  31
ASP A  53
GLY A  58
 None
 1.24A 5mraA-2il5A:
undetectable
5mraB-2il5A:
undetectable		 5mraA-2il5A:
20.00
5mraB-2il5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 2il5 HYPOTHETICAL PROTEIN
(Staphylococcus
aureus) 		5 / 12 VAL A 148
GLY A 150
TRP A  30
PHE A 119
PHE A 155
 None
 1.32A 6a94A-2il5A:
undetectable		 6a94A-2il5A:
17.96