SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ilu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 8 LEU A 371
ALA A 393
GLY A 296
ILE A 297
 None
 0.74A 1d4sB-2iluA:
undetectable		 1d4sB-2iluA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		3 / 3 TRP A  60
ARG A 161
THR A 169
 None
 0.95A 1df7A-2iluA:
undetectable		 1df7A-2iluA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 8 VAL A 373
VAL A 391
ILE A 273
LEU A 369
 None
 0.90A 1igxA-2iluA:
undetectable		 1igxA-2iluA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 7 GLY A  94
GLN A 283
ILE A  90
PRO A 155
 None
 0.96A 1rxcC-2iluA:
2.0		 1rxcC-2iluA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 7 GLY A  94
GLN A 283
ILE A  90
PRO A 155
 None
 1.00A 1rxcD-2iluA:
undetectable		 1rxcD-2iluA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 7 GLY A  94
GLN A 283
ILE A  90
PRO A 155
 None
 1.04A 1rxcF-2iluA:
undetectable		 1rxcF-2iluA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 8 GLY A  94
GLN A 283
ILE A  90
PRO A 155
 None
 0.98A 1rxcI-2iluA:
undetectable		 1rxcI-2iluA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 7 GLY A  94
GLN A 283
ILE A  90
PRO A 155
 None
 1.03A 1rxcL-2iluA:
undetectable		 1rxcL-2iluA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 5 VAL A 212
THR A 211
GLN A  42
ILE A  24
 None
 1.23A 1ss4A-2iluA:
undetectable		 1ss4A-2iluA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 11 VAL A 293
VAL A 260
TYR A 416
LEU A 389
ILE A 273
 None
 1.43A 1t6zB-2iluA:
2.7		 1t6zB-2iluA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		6 / 11 ALA A  46
ASP A  45
ILE A  11
ILE A 175
VAL A 145
ILE A  50
 None
 1.33A 2fxeB-2iluA:
undetectable		 2fxeB-2iluA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 6 SER A 407
SER A 455
LEU A 411
GLY A 410
 SO4  A 480 ( 4.8A)
SO4  A 480 ( 3.7A)
SO4  A 480 (-4.3A)
SO4  A 480 (-2.9A)
 1.01A 2j2pA-2iluA:
undetectable
2j2pC-2iluA:
undetectable		 2j2pA-2iluA:
16.37
2j2pC-2iluA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 6 SER A 407
SER A 455
LEU A 411
GLY A 410
 SO4  A 480 ( 4.8A)
SO4  A 480 ( 3.7A)
SO4  A 480 (-4.3A)
SO4  A 480 (-2.9A)
 1.00A 2j2pD-2iluA:
undetectable
2j2pF-2iluA:
undetectable		 2j2pD-2iluA:
16.37
2j2pF-2iluA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		6 / 12 ALA A  46
ASP A  45
ILE A  11
ILE A 175
VAL A 145
ILE A  50
 None
 1.31A 2o4kB-2iluA:
undetectable		 2o4kB-2iluA:
12.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		6 / 7 LEU A 100
PHE A 107
PHE A 154
ILE A 279
ASN A 286
GLU A 443
 None
 0.83A 2opxA-2iluA:
62.7		 2opxA-2iluA:
99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 7 LEU A 100
PHE A 157
ILE A 279
ASN A 286
GLU A 443
 None
 1.26A 2opxA-2iluA:
62.7		 2opxA-2iluA:
99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		3 / 3 GLY A 315
ARG A 320
TYR A 364
 None
 0.54A 2opxA-2iluA:
62.7		 2opxA-2iluA:
99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 5 ILE A  97
LEU A 100
ASP A 275
ALA A 324
 None
 0.59A 2opxA-2iluA:
62.7		 2opxA-2iluA:
99.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 12 TYR A 111
ALA A 166
THR A 169
LEU A 466
MET A 445
 None
 1.36A 2x2nD-2iluA:
undetectable		 2x2nD-2iluA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 11 VAL A  91
GLY A  95
ILE A 329
PRO A  29
THR A  31
 None
None
NDP  A 482 (-4.9A)
None
None
 1.14A 3bjwB-2iluA:
undetectable		 3bjwB-2iluA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 11 VAL A  91
GLY A  95
ILE A 329
PRO A  29
THR A  31
 None
None
NDP  A 482 (-4.9A)
None
None
 1.13A 3bjwH-2iluA:
undetectable		 3bjwH-2iluA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		6 / 12 ALA A  46
ASP A  45
ILE A  11
ILE A 175
VAL A 145
ILE A  50
 None
 1.31A 3d1xA-2iluA:
undetectable		 3d1xA-2iluA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 9 ASP A  45
ILE A  11
ILE A 175
VAL A 145
ILE A  50
 None
 1.30A 3ekyB-2iluA:
undetectable		 3ekyB-2iluA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 5 PRO A 198
THR A 146
VAL A 145
GLY A 144
 None
 1.13A 3elzA-2iluA:
undetectable		 3elzA-2iluA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 9 LEU A 167
LEU A 197
VAL A 192
ILE A 112
PHE A 188
 None
 1.25A 3freX-2iluA:
undetectable		 3freX-2iluA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		6 / 12 ALA A  46
ASP A  45
ILE A  11
ILE A 175
VAL A 145
ILE A  50
 None
 1.27A 3jw2B-2iluA:
undetectable		 3jw2B-2iluA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		6 / 12 ALA A  46
ASP A  45
ILE A  11
ILE A 175
VAL A 145
ILE A  50
 None
 1.41A 3k4vA-2iluA:
undetectable		 3k4vA-2iluA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 5 SER A 276
ARG A 277
ARG A 290
GLY A 254
 None
None
None
SO4  A 480 (-3.1A)
 1.34A 3k9fA-2iluA:
undetectable
3k9fB-2iluA:
undetectable
3k9fC-2iluA:
1.9		 3k9fA-2iluA:
24.07
3k9fB-2iluA:
24.07
3k9fC-2iluA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		6 / 9 ALA A  46
ASP A  45
ILE A  11
ILE A 175
VAL A 145
ILE A  50
 None
 1.33A 3ndwB-2iluA:
undetectable		 3ndwB-2iluA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		6 / 11 ALA A  46
ASP A  45
ILE A  11
ILE A 175
VAL A 145
ILE A  50
 None
 1.34A 3ndxB-2iluA:
undetectable		 3ndxB-2iluA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 5 PHE A 107
ILE A  90
ASN A 441
PHE A 156
 None
 1.23A 3octA-2iluA:
undetectable		 3octA-2iluA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		6 / 12 GLY A 253
VAL A 284
ASN A 153
ALA A 256
LEU A 250
LEU A 411
 None
None
None
SO4  A 480 (-3.8A)
OCS  A 249 ( 3.7A)
SO4  A 480 (-4.3A)
 1.25A 3p2kC-2iluA:
4.3		 3p2kC-2iluA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 8 ASN A 203
GLY A 200
ALA A  53
GLY A 144
THR A 147
 None
 1.30A 3so9A-2iluA:
undetectable		 3so9A-2iluA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 7 LEU A 371
ALA A 393
GLY A 296
ILE A 297
 None
 0.82A 3spkB-2iluA:
undetectable		 3spkB-2iluA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		6 / 12 ALA A  46
ASP A  45
ILE A  11
ILE A 175
VAL A 145
ILE A  50
 None
 1.40A 3tl9A-2iluA:
undetectable		 3tl9A-2iluA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 8 GLY A  94
GLN A 283
ILE A  90
PRO A 155
 None
 0.98A 4e1vA-2iluA:
2.3		 4e1vA-2iluA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 7 GLY A  94
GLN A 283
ILE A  90
PRO A 155
 None
 0.97A 4e1vB-2iluA:
undetectable		 4e1vB-2iluA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 8 GLY A  94
GLN A 283
ILE A  90
PRO A 155
 None
 1.01A 4e1vH-2iluA:
undetectable		 4e1vH-2iluA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 8 GLU A 104
GLN A 283
GLY A 282
SER A 281
 None
 1.01A 4f93B-2iluA:
undetectable		 4f93B-2iluA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 7 TRP A 152
GLY A 253
GLY A 254
GLU A 251
 NDP  A 482 (-4.1A)
None
SO4  A 480 (-3.1A)
None
 0.90A 4fgkB-2iluA:
undetectable		 4fgkB-2iluA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 12 GLY A 229
GLY A 253
LEU A 250
ALA A 233
ILE A 149
 NDP  A 482 (-3.5A)
None
OCS  A 249 ( 3.7A)
NDP  A 482 (-3.2A)
NDP  A 482 (-4.1A)
 1.12A 4krhB-2iluA:
4.8		 4krhB-2iluA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 5 TYR A 298
THR A 435
LEU A 430
THR A 396
 None
 1.46A 4mbsB-2iluA:
undetectable		 4mbsB-2iluA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		3 / 3 GLY A 326
PRO A 327
GLN A 283
 None
 0.25A 4oltB-2iluA:
undetectable		 4oltB-2iluA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		3 / 3 GLY A 326
PRO A 327
GLN A 283
 None
 0.30A 4qwpB-2iluA:
undetectable		 4qwpB-2iluA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		3 / 3 ILE A  38
PRO A  39
ILE A  24
 None
 0.41A 5hw8F-2iluA:
undetectable		 5hw8F-2iluA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		3 / 3 GLY A  94
GLY A  95
GLN A 283
 None
 0.41A 5imsA-2iluA:
2.8		 5imsA-2iluA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		4 / 7 GLY A 253
GLY A 229
LEU A 158
GLU A 289
 None
NDP  A 482 (-3.5A)
None
None
 0.84A 5izfA-2iluA:
undetectable		 5izfA-2iluA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 12 ASN A 183
ILE A 186
ALA A 187
LYS A 190
ILE A  24
 None
 0.66A 5j2tC-2iluA:
undetectable		 5j2tC-2iluA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 11 ILE A  86
ILE A 191
VAL A 105
THR A 108
ALA A  77
 None
 1.14A 5lg3A-2iluA:
undetectable		 5lg3A-2iluA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		5 / 10 LEU A  72
ILE A 112
ALA A 160
PHE A 188
VAL A 192
 None
 1.35A 5m0oA-2iluA:
undetectable		 5m0oA-2iluA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2ilu ALDEHYDE
DEHYDROGENASE A
(Escherichia
coli) 		3 / 3 ALA A 166
GLN A  57
THR A 146
 None
 0.73A 5n0oA-2iluA:
undetectable		 5n0oA-2iluA:
23.03