SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ilx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		4 / 4 HIS A 150
LEU A  70
LEU A  22
LEU A 204
 None
 1.15A 1a4lD-2ilxA:
undetectable		 1a4lD-2ilxA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		5 / 12 VAL A 151
ILE A 106
LEU A 204
VAL A 210
LEU A  14
 None
 1.05A 2jn3A-2ilxA:
undetectable		 2jn3A-2ilxA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		5 / 12 LEU A 192
GLY A  26
GLN A  27
PHE A  39
VAL A 151
 None
 1.34A 2w8yA-2ilxA:
undetectable		 2w8yA-2ilxA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		5 / 12 LEU A  70
LEU A  22
ARG A  23
ALA A  25
LEU A  30
 None
 1.22A 3gwuA-2ilxA:
undetectable		 3gwuA-2ilxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		5 / 11 PHE A 110
PHE A  46
GLY A 196
LEU A 192
PHE A  39
 None
 1.13A 3t3rA-2ilxA:
undetectable		 3t3rA-2ilxA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		4 / 5 LEU A  70
SER A  18
LEU A 104
LEU A 153
 None
 1.29A 4n09D-2ilxA:
undetectable		 4n09D-2ilxA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		4 / 5 THR A 115
THR A 164
THR A  73
HIS A  71
 None
 1.21A 4pgfB-2ilxA:
undetectable		 4pgfB-2ilxA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		4 / 5 GLY A  80
TYR A   9
GLU A  86
ASP A  78
 None
 1.12A 4xueA-2ilxA:
undetectable		 4xueA-2ilxA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		4 / 8 GLN A 119
LEU A 169
LEU A 168
THR A 112
 None
 0.94A 5hs6A-2ilxA:
undetectable		 5hs6A-2ilxA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		3 / 3 LYS A 103
LEU A  70
ILE A 106
 None
 0.66A 5kc0A-2ilxA:
undetectable		 5kc0A-2ilxA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		3 / 3 LYS A 103
LEU A  70
ILE A 106
 None
 0.68A 5kc4A-2ilxA:
undetectable		 5kc4A-2ilxA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		5 / 7 GLY A 165
LEU A 153
ILE A 171
LEU A 172
ILE A 106
 None
 1.02A 5vkqA-2ilxA:
undetectable
5vkqB-2ilxA:
undetectable		 5vkqA-2ilxA:
8.74
5vkqB-2ilxA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		5 / 9 GLY A 165
LEU A 153
ILE A 171
LEU A 172
ILE A 106
 None
 0.97A 5vkqC-2ilxA:
undetectable
5vkqD-2ilxA:
undetectable		 5vkqC-2ilxA:
8.74
5vkqD-2ilxA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 2ilx 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Rattus
norvegicus) 		4 / 5 THR A 164
THR A  73
HIS A  71
GLY A 117
 None
 1.02A 6gbnC-2ilxA:
undetectable		 6gbnC-2ilxA:
18.82