SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2imh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 9 LEU A   6
ILE A 114
LEU A  59
VAL A  69
ALA A  95
 None
 1.26A 1e7aA-2imhA:
undetectable		 1e7aA-2imhA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 12 ALA A 164
LEU A 161
PHE A   3
SER A   0
VAL A  30
 None
 1.31A 1u72A-2imhA:
undetectable		 1u72A-2imhA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 9 GLU A 141
LEU A  89
LEU A  35
ARG A 173
ALA A  14
 None
 1.38A 2bxcB-2imhA:
undetectable		 2bxcB-2imhA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 11 ALA A  41
ILE A   5
GLY A  16
ILE A  15
ALA A  93
 None
 1.09A 2idwA-2imhA:
undetectable		 2idwA-2imhA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 8 LEU A  59
ASP A  88
ILE A  15
GLY A 113
ILE A 114
 None
 1.31A 2o4nB-2imhA:
undetectable		 2o4nB-2imhA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 8 ALA A 151
MET A 129
GLY A 121
LEU A 120
GLY A 117
 None
 1.21A 2yfxA-2imhA:
undetectable		 2yfxA-2imhA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_A_TESA339_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 10 THR A  21
SER A  23
TRP A  29
VAL A  26
VAL A  30
 None
 1.45A 3burA-2imhA:
undetectable		 3burA-2imhA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 12 LEU A 161
ALA A  18
ALA A 146
GLY A 153
GLU A 152
 None
 1.10A 3c6gB-2imhA:
undetectable		 3c6gB-2imhA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		4 / 6 GLU A 152
ILE A 149
PHE A   3
ALA A 151
 None
 1.06A 3pgyA-2imhA:
undetectable
3pgyB-2imhA:
undetectable		 3pgyA-2imhA:
19.33
3pgyB-2imhA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 11 LEU A 191
LEU A 145
ILE A 188
SER A 136
LEU A  31
 None
 1.12A 4dm8A-2imhA:
undetectable		 4dm8A-2imhA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 12 LEU A 191
LEU A 145
ILE A 188
SER A 136
LEU A  31
 None
 1.08A 4dm8B-2imhA:
undetectable		 4dm8B-2imhA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		3 / 3 LEU A 144
MET A 166
ASP A  88
 None
 0.76A 4j7xB-2imhA:
undetectable		 4j7xB-2imhA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 12 ALA A  85
GLY A 117
LEU A   1
LEU A 120
ALA A  41
 None
 1.12A 4lg1B-2imhA:
undetectable		 4lg1B-2imhA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 12 ALA A  85
GLY A 117
LEU A   1
LEU A 120
ALA A  41
 None
 1.10A 4lg1C-2imhA:
undetectable		 4lg1C-2imhA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		4 / 4 GLY A  17
ALA A  19
MET A 129
THR A   2
 None
 1.23A 5n0sB-2imhA:
undetectable		 5n0sB-2imhA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		4 / 4 GLY A  17
ALA A  19
MET A 129
THR A  21
 None
 1.23A 5n0sB-2imhA:
undetectable		 5n0sB-2imhA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		5 / 12 VAL A  26
LEU A 161
LEU A 148
ILE A   5
ALA A  18
 None
 1.34A 5xprA-2imhA:
undetectable		 5xprA-2imhA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 2imh HYPOTHETICAL PROTEIN
UNP Q5LQD5_SILPO
(Ruegeria
pomeroyi) 		3 / 3 VAL A  30
ALA A  19
GLN A  43
 None
 0.69A 6gb9A-2imhA:
undetectable		 6gb9A-2imhA:
20.48