SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2imj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 2imj HYPOTHETICAL PROTEIN
DUF1348
(Pseudomonas
protegens) 		3 / 3 ALA A  83
VAL A  91
TRP A 113
 None
 0.55A 1kqeA-2imjA:
undetectable
1kqeE-2imjA:
undetectable		 1kqeA-2imjA:
11.39
1kqeE-2imjA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 2imj HYPOTHETICAL PROTEIN
DUF1348
(Pseudomonas
protegens) 		3 / 3 ALA A  83
VAL A  91
TRP A 113
 None
 0.56A 1kqeB-2imjA:
undetectable
1kqeD-2imjA:
undetectable		 1kqeB-2imjA:
11.39
1kqeD-2imjA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 2imj HYPOTHETICAL PROTEIN
DUF1348
(Pseudomonas
protegens) 		3 / 3 TRP A 113
ALA A  83
VAL A  91
 None
 0.57A 1kqeB-2imjA:
undetectable
1kqeD-2imjA:
undetectable		 1kqeB-2imjA:
11.39
1kqeD-2imjA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 2imj HYPOTHETICAL PROTEIN
DUF1348
(Pseudomonas
protegens) 		3 / 3 TRP A 113
ALA A  83
VAL A  91
 None
 0.59A 1kqeA-2imjA:
undetectable
1kqeE-2imjA:
undetectable		 1kqeA-2imjA:
11.39
1kqeE-2imjA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 2imj HYPOTHETICAL PROTEIN
DUF1348
(Pseudomonas
protegens) 		3 / 3 ALA A  83
VAL A  91
TRP A 113
 None
 0.63A 1micA-2imjA:
undetectable
1micB-2imjA:
undetectable		 1micA-2imjA:
10.84
1micB-2imjA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 2imj HYPOTHETICAL PROTEIN
DUF1348
(Pseudomonas
protegens) 		4 / 7 ARG A  51
TYR A  93
TYR A  95
LEU A  77
 None
ACT  A 201 (-4.0A)
ACT  A 201 (-3.8A)
ACT  A 201 ( 4.6A)
 1.40A 4f8yC-2imjA:
undetectable
4f8yD-2imjA:
undetectable		 4f8yC-2imjA:
23.53
4f8yD-2imjA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 2imj HYPOTHETICAL PROTEIN
DUF1348
(Pseudomonas
protegens) 		4 / 7 TYR A  93
TYR A  95
LEU A  77
TYR A  42
 ACT  A 201 (-4.0A)
ACT  A 201 (-3.8A)
ACT  A 201 ( 4.6A)
None
 1.28A 4f8yC-2imjA:
undetectable
4f8yD-2imjA:
undetectable		 4f8yC-2imjA:
23.53
4f8yD-2imjA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 2imj HYPOTHETICAL PROTEIN
DUF1348
(Pseudomonas
protegens) 		3 / 3 ARG A 147
TRP A 142
ILE A  78
 None
 0.97A 4mwxA-2imjA:
undetectable		 4mwxA-2imjA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 2imj HYPOTHETICAL PROTEIN
DUF1348
(Pseudomonas
protegens) 		3 / 3 LEU A  81
LEU A  77
ASN A 110
 None
ACT  A 201 ( 4.6A)
None
 0.77A 4otwA-2imjA:
1.8		 4otwA-2imjA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2imj HYPOTHETICAL PROTEIN
DUF1348
(Pseudomonas
protegens) 		4 / 8 ASN A  50
PHE A  64
TRP A  48
TRP A  30
 None
None
None
ACT  A 201 (-4.2A)
 1.00A 5amkA-2imjA:
undetectable		 5amkA-2imjA:
19.25