SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2imr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  97
HIS A  99
HIS A 238
GLU A 241
HIS A 301
ASP A 352
 ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
 0.57A 1a4lA-2imrA:
15.6		 1a4lA-2imrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  97
HIS A  99
PHE A 113
HIS A 238
HIS A 301
ASP A 352
 ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.9A)
 0.94A 1a4lA-2imrA:
15.6		 1a4lA-2imrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  97
PHE A 107
HIS A 238
GLU A 241
HIS A 301
ASP A 352
 ZN  A 500 (-3.3A)
None
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
 0.83A 1a4lA-2imrA:
15.6		 1a4lA-2imrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
PHE A 107
HIS A 238
GLU A 241
HIS A 301
ASP A 352
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
 0.81A 1a4lB-2imrA:
17.6		 1a4lB-2imrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
PHE A 113
LEU A 110
HIS A 238
HIS A 301
ASP A 352
 ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.9A)
 0.97A 1a4lB-2imrA:
17.6		 1a4lB-2imrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
PHE A 113
PHE A 107
HIS A 238
HIS A 301
ASP A 352
 ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.9A)
 0.98A 1a4lB-2imrA:
17.6		 1a4lB-2imrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  97
HIS A  99
HIS A 238
GLU A 241
HIS A 301
ASP A 352
 ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
 0.50A 1a4lC-2imrA:
17.8		 1a4lC-2imrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  97
HIS A  99
PHE A 113
HIS A 238
HIS A 301
ASP A 352
 ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.9A)
 0.86A 1a4lC-2imrA:
17.8		 1a4lC-2imrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  97
PHE A 107
HIS A 238
GLU A 241
HIS A 301
ASP A 352
 ZN  A 500 (-3.3A)
None
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
 0.87A 1a4lC-2imrA:
17.8		 1a4lC-2imrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
PHE A 107
HIS A 238
GLU A 241
HIS A 301
ASP A 352
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
 0.84A 1a4lD-2imrA:
17.6		 1a4lD-2imrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 HIS A  99
PHE A 113
HIS A 238
HIS A 301
ASP A 352
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.9A)
 0.90A 1a4lD-2imrA:
17.6		 1a4lD-2imrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		4 / 4 HIS A 238
GLU A 173
HIS A  99
HIS A  97
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
ZN  A 500 (-3.3A)
 1.30A 1uttA-2imrA:
undetectable		 1uttA-2imrA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 8 ARG A 379
VAL A 347
LEU A 349
VAL A 366
VAL A  43
 None
 1.50A 2bdmA-2imrA:
undetectable		 2bdmA-2imrA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		4 / 8 ASP A 165
LEU A 139
LEU A 160
LEU A 170
 None
 0.96A 2bfpC-2imrA:
2.9		 2bfpC-2imrA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		3 / 3 PRO A 277
THR A 251
PRO A 279
 None
 0.82A 2d55C-2imrA:
undetectable		 2d55C-2imrA:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		4 / 8 VAL A 174
VAL A 185
LEU A 175
PRO A 177
 None
 1.05A 2ddwA-2imrA:
undetectable		 2ddwA-2imrA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		4 / 7 SER A 167
THR A 397
PRO A 398
GLY A 389
 None
 0.76A 2ddwB-2imrA:
undetectable		 2ddwB-2imrA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		4 / 6 LEU A 233
LEU A 193
PRO A 210
VAL A 174
 None
 1.11A 2dqyC-2imrA:
undetectable		 2dqyC-2imrA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		3 / 3 VAL A  60
TRP A 406
VAL A  64
 None
 0.87A 2izqA-2imrA:
undetectable
2izqB-2imrA:
undetectable		 2izqA-2imrA:
6.03
2izqB-2imrA:
6.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 9 THR A 212
HIS A 238
HIS A  97
HIS A  99
LEU A 175
 None
ZN  A 500 (-3.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
None
 1.30A 2jihA-2imrA:
undetectable		 2jihA-2imrA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
PHE A 113
HIS A 238
HIS A 301
SER A 326
ASP A 352
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
 0.96A 2pgfA-2imrA:
18.5		 2pgfA-2imrA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  97
HIS A  99
HIS A 238
GLU A 241
HIS A 301
ASP A 352
 ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
 0.44A 2pgrA-2imrA:
18.4		 2pgrA-2imrA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  97
HIS A  99
PHE A 113
HIS A 238
HIS A 301
ASP A 352
 ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.9A)
 0.78A 2pgrA-2imrA:
18.4		 2pgrA-2imrA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 8 ASP A 149
ASP A 101
GLU A 173
SER A 209
HIS A 238
 None
None
None
None
ZN  A 500 (-3.2A)
 1.49A 2q0iA-2imrA:
undetectable		 2q0iA-2imrA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 11 HIS A  99
ILE A 150
HIS A  97
HIS A 301
PRO A 213
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.3A)
None
None
 1.43A 2zwfA-2imrA:
undetectable
2zwfB-2imrA:
undetectable		 2zwfA-2imrA:
20.18
2zwfB-2imrA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 11 HIS A  99
ILE A 150
HIS A  97
HIS A 301
PRO A 213
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.3A)
None
None
 1.41A 2zwgA-2imrA:
undetectable
2zwgB-2imrA:
0.3		 2zwgA-2imrA:
20.18
2zwgB-2imrA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M8P_A_65BA562_0
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 11 LEU A 193
VAL A 151
VAL A 174
TYR A 171
LEU A 206
 None
 1.29A 3m8pA-2imrA:
2.6
3m8pB-2imrA:
2.3		 3m8pA-2imrA:
20.61
3m8pB-2imrA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		3 / 3 HIS A  99
HIS A  97
HIS A 238
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.57A 3qpkA-2imrA:
undetectable		 3qpkA-2imrA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		3 / 3 HIS A  99
HIS A  97
HIS A 238
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.55A 3qpkB-2imrA:
undetectable		 3qpkB-2imrA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 HIS A 238
GLU A 241
HIS A 301
SER A 326
ASP A 352
 ZN  A 500 (-3.2A)
None
None
None
ZN  A 500 (-3.9A)
 0.42A 4aqlA-2imrA:
26.7		 4aqlA-2imrA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 LEU A 110
HIS A 238
HIS A 301
SER A 326
ASP A 352
 None
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
 0.76A 4aqlA-2imrA:
26.7		 4aqlA-2imrA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 LEU A 372
TRP A 337
ALA A 384
GLY A 350
LEU A 349
 None
 1.13A 4j7xB-2imrA:
3.0		 4j7xB-2imrA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		3 / 3 ALA A  51
GLN A 390
GLY A 394
 None
 0.63A 4odoC-2imrA:
undetectable		 4odoC-2imrA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		3 / 3 LEU A 126
LEU A 170
ASN A  95
 None
 0.69A 4otwA-2imrA:
undetectable		 4otwA-2imrA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
HIS A 238
HIS A 301
LEU A 330
ASP A 352
SER A 353
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
None
 0.60A 4r88A-2imrA:
22.7		 4r88A-2imrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
LEU A 110
HIS A 238
HIS A 301
ASP A 352
SER A 353
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.9A)
None
 0.94A 4r88A-2imrA:
22.7		 4r88A-2imrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
HIS A 238
GLU A 241
LEU A 330
ASP A 352
SER A 353
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
None
 0.66A 4r88B-2imrA:
23.5		 4r88B-2imrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
HIS A 238
GLU A 241
LEU A 330
ASP A 352
SER A 353
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
None
 0.64A 4r88C-2imrA:
21.4		 4r88C-2imrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
HIS A 238
GLU A 241
LEU A 330
ASP A 352
SER A 353
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
None
 0.65A 4r88D-2imrA:
17.9		 4r88D-2imrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 HIS A  99
LEU A 110
HIS A 238
ASP A 352
SER A 353
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
ZN  A 500 (-3.9A)
None
 0.85A 4r88D-2imrA:
17.9		 4r88D-2imrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
HIS A 238
GLU A 241
LEU A 330
ASP A 352
SER A 353
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
None
 0.65A 4r88E-2imrA:
23.5		 4r88E-2imrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 HIS A  99
LEU A 110
HIS A 238
ASP A 352
SER A 353
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
ZN  A 500 (-3.9A)
None
 0.84A 4r88E-2imrA:
23.5		 4r88E-2imrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		6 / 12 HIS A  99
HIS A 238
GLU A 241
LEU A 330
ASP A 352
SER A 353
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.2A)
None
None
ZN  A 500 (-3.9A)
None
 0.66A 4r88F-2imrA:
8.9		 4r88F-2imrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		3 / 3 ASP A 226
LEU A 290
GLY A 291
 None
 0.26A 4xmfA-2imrA:
undetectable		 4xmfA-2imrA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		4 / 6 SER A 209
GLU A 173
GLY A 394
GLY A 168
 None
 0.96A 5cdpA-2imrA:
undetectable
5cdpB-2imrA:
undetectable		 5cdpA-2imrA:
22.02
5cdpB-2imrA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_A_5D5A930_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 ASP A 309
THR A 282
PHE A 249
LEU A 246
PRO A 255
 None
 1.39A 5dlvA-2imrA:
undetectable		 5dlvA-2imrA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 ASP A 309
THR A 282
PHE A 249
LEU A 246
PRO A 255
 None
 1.39A 5dlvB-2imrA:
undetectable		 5dlvB-2imrA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 PRO A 234
LEU A 208
GLY A 168
GLU A 200
LEU A 206
 None
 1.39A 5emlA-2imrA:
5.6		 5emlA-2imrA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 GLY A 350
GLY A 357
GLY A 148
HIS A  99
LEU A 126
 None
None
None
ZN  A 500 (-3.2A)
None
 0.99A 5gwxA-2imrA:
undetectable		 5gwxA-2imrA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 LEU A 330
CYH A 332
GLY A 333
PHE A 214
LEU A 110
 None
 1.40A 5kklB-2imrA:
undetectable		 5kklB-2imrA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		4 / 5 VAL A 354
THR A 351
ASN A  95
LEU A 360
 None
 1.30A 5m0iB-2imrA:
undetectable		 5m0iB-2imrA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		3 / 3 HIS A  99
HIS A  97
HIS A 238
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.59A 5migA-2imrA:
undetectable		 5migA-2imrA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		4 / 8 PRO A 266
ALA A 109
THR A 215
ALA A 182
 None
 1.00A 5x2tI-2imrA:
undetectable
5x2tJ-2imrA:
undetectable
5x2tK-2imrA:
undetectable
5x2tL-2imrA:
undetectable		 5x2tI-2imrA:
15.95
5x2tJ-2imrA:
17.35
5x2tK-2imrA:
15.95
5x2tL-2imrA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 11 HIS A  99
ILE A 150
HIS A  97
HIS A 301
PRO A 213
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.3A)
None
None
 1.41A 5z0hA-2imrA:
undetectable
5z0hB-2imrA:
undetectable		 5z0hA-2imrA:
12.71
5z0hB-2imrA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 11 HIS A  99
ILE A 150
HIS A  97
HIS A 301
PRO A 213
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.3A)
None
None
 1.41A 5z0lA-2imrA:
undetectable
5z0lB-2imrA:
undetectable		 5z0lA-2imrA:
12.71
5z0lB-2imrA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 11 HIS A  99
ILE A 150
HIS A  97
HIS A 301
PRO A 213
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.3A)
None
None
 1.26A 5z0mA-2imrA:
undetectable
5z0mB-2imrA:
undetectable		 5z0mA-2imrA:
12.71
5z0mB-2imrA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		3 / 3 ARG A 296
ARG A 205
ARG A 391
 None
 0.78A 6bplA-2imrA:
undetectable
6bplB-2imrA:
1.6		 6bplA-2imrA:
11.65
6bplB-2imrA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		3 / 3 VAL A 392
ALA A 348
GLN A 236
 None
 0.68A 6gb9A-2imrA:
undetectable		 6gb9A-2imrA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 HIS A  99
LEU A 110
HIS A 238
HIS A 301
ASP A 352
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.9A)
 0.97A 6n91A-2imrA:
19.0		 6n91A-2imrA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 2imr HYPOTHETICAL PROTEIN
DR_0824
(Deinococcus
radiodurans) 		5 / 12 HIS A  99
LEU A 110
HIS A 238
HIS A 301
ASP A 352
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.9A)
 1.05A 6n91B-2imrA:
19.0		 6n91B-2imrA:
12.95