SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2in3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.82A 1grmA-2in3A:
undetectable		 1grmA-2in3A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.82A 1grmB-2in3A:
undetectable		 1grmB-2in3A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.90A 1jnoA-2in3A:
undetectable		 1jnoA-2in3A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.90A 1jnoB-2in3A:
undetectable		 1jnoB-2in3A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.83A 1jo4A-2in3A:
undetectable		 1jo4A-2in3A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.83A 1jo4B-2in3A:
undetectable		 1jo4B-2in3A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.76A 1magA-2in3A:
undetectable		 1magA-2in3A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.76A 1magB-2in3A:
undetectable		 1magB-2in3A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.91A 1ng8A-2in3A:
undetectable		 1ng8A-2in3A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.91A 1ng8B-2in3A:
undetectable		 1ng8B-2in3A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.81A 1nrmA-2in3A:
undetectable		 1nrmA-2in3A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.81A 1nrmB-2in3A:
undetectable		 1nrmB-2in3A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.83A 1nt6A-2in3A:
undetectable		 1nt6A-2in3A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 ALA A 119
VAL A 122
TRP A  20
 None
 0.83A 1nt6B-2in3A:
undetectable		 1nt6B-2in3A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 11 PHE A 164
SER A 100
PHE A 147
LEU A 133
VAL A 127
 None
 1.22A 1q23J-2in3A:
undetectable		 1q23J-2in3A:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 7 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.91A 1v55P-2in3A:
undetectable
1v55W-2in3A:
undetectable		 1v55P-2in3A:
22.22
1v55W-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 7 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 1.00A 2dysC-2in3A:
undetectable
2dysJ-2in3A:
undetectable		 2dysC-2in3A:
22.22
2dysJ-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 7 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.91A 2eijP-2in3A:
undetectable
2eijW-2in3A:
undetectable		 2eijP-2in3A:
22.22
2eijW-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 8 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.87A 2eilP-2in3A:
undetectable
2eilW-2in3A:
undetectable		 2eilP-2in3A:
22.22
2eilW-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		3 / 3 GLN A 117
THR A  73
TRP A  18
 None
None
GOL  A 220 (-3.5A)
 1.15A 2rctA-2in3A:
undetectable		 2rctA-2in3A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 11 ASP A 139
VAL A 127
ILE A 116
PRO A  14
VAL A 101
 None
 1.44A 2vcdA-2in3A:
undetectable		 2vcdA-2in3A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 6 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.94A 2zxwP-2in3A:
undetectable
2zxwW-2in3A:
undetectable		 2zxwP-2in3A:
22.22
2zxwW-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 5 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 1.00A 3ablC-2in3A:
undetectable
3ablJ-2in3A:
undetectable		 3ablC-2in3A:
22.22
3ablJ-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 6 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.96A 3ag1C-2in3A:
undetectable
3ag1J-2in3A:
undetectable		 3ag1C-2in3A:
22.22
3ag1J-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 8 ILE A  26
PHE A 110
THR A 190
LEU A 203
 None
 0.74A 3ua5A-2in3A:
undetectable		 3ua5A-2in3A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 LEU A 178
LEU A   8
ILE A  29
TYR A  33
PHE A  36
 None
 1.06A 4a7aB-2in3A:
undetectable		 4a7aB-2in3A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_B_TOPB202_1
(DIHYDROFOLATE
REDUCTASE)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 12 PHE A  22
LEU A 203
LEU A 178
ILE A  26
THR A  73
 None
 1.11A 4km2B-2in3A:
undetectable		 4km2B-2in3A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		6 / 11 LEU A 199
ARG A 200
LEU A 203
LEU A 178
LEU A   8
TYR A  33
 None
 1.16A 4wg0B-2in3A:
undetectable
4wg0C-2in3A:
undetectable
4wg0D-2in3A:
undetectable		 4wg0B-2in3A:
4.78
4wg0C-2in3A:
4.78
4wg0D-2in3A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		6 / 11 LEU A 199
ARG A 200
LEU A 203
LEU A 178
LEU A   8
TYR A  33
 None
 1.16A 4wg0D-2in3A:
undetectable
4wg0E-2in3A:
undetectable
4wg0F-2in3A:
undetectable		 4wg0D-2in3A:
4.78
4wg0E-2in3A:
4.78
4wg0F-2in3A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		6 / 11 LEU A   8
TYR A  33
LEU A 178
LEU A 199
ARG A 200
LEU A 203
 None
 1.21A 4wg0C-2in3A:
undetectable
4wg0D-2in3A:
undetectable
4wg0E-2in3A:
undetectable		 4wg0C-2in3A:
4.78
4wg0D-2in3A:
4.78
4wg0E-2in3A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 11 LEU A 199
LEU A 203
LEU A 178
LEU A   8
TYR A  33
 None
 1.17A 4wg0F-2in3A:
undetectable
4wg0G-2in3A:
undetectable
4wg0H-2in3A:
undetectable		 4wg0F-2in3A:
4.78
4wg0G-2in3A:
4.78
4wg0H-2in3A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		6 / 11 LEU A   8
TYR A  33
LEU A 178
LEU A 199
ARG A 200
LEU A 203
 None
 1.20A 4wg0E-2in3A:
undetectable
4wg0F-2in3A:
undetectable
4wg0G-2in3A:
undetectable		 4wg0E-2in3A:
4.78
4wg0F-2in3A:
4.78
4wg0G-2in3A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 11 ARG A 200
LEU A 203
LEU A 178
LEU A   8
TYR A  33
 None
 1.22A 4wg0H-2in3A:
undetectable
4wg0I-2in3A:
undetectable
4wg0J-2in3A:
undetectable		 4wg0H-2in3A:
4.78
4wg0I-2in3A:
4.78
4wg0J-2in3A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 11 LEU A 199
LEU A 203
LEU A 178
LEU A   8
TYR A  33
 None
 1.18A 4wg0H-2in3A:
undetectable
4wg0I-2in3A:
undetectable
4wg0J-2in3A:
undetectable		 4wg0H-2in3A:
4.78
4wg0I-2in3A:
4.78
4wg0J-2in3A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		6 / 11 LEU A   8
TYR A  33
LEU A 178
LEU A 199
ARG A 200
LEU A 203
 None
 1.19A 4wg0G-2in3A:
undetectable
4wg0H-2in3A:
undetectable
4wg0I-2in3A:
undetectable		 4wg0G-2in3A:
4.78
4wg0H-2in3A:
4.78
4wg0I-2in3A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		6 / 11 LEU A 199
ARG A 200
LEU A 203
LEU A 178
LEU A   8
TYR A  33
 None
 1.19A 4wg0J-2in3A:
undetectable
4wg0K-2in3A:
undetectable
4wg0L-2in3A:
undetectable		 4wg0J-2in3A:
4.78
4wg0K-2in3A:
4.78
4wg0L-2in3A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		6 / 11 LEU A   8
TYR A  33
LEU A 178
LEU A 199
ARG A 200
LEU A 203
 None
 1.24A 4wg0I-2in3A:
undetectable
4wg0J-2in3A:
undetectable
4wg0K-2in3A:
undetectable		 4wg0I-2in3A:
4.78
4wg0J-2in3A:
4.78
4wg0K-2in3A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		5 / 11 LEU A   8
TYR A  33
LEU A 178
LEU A 199
LEU A 203
 None
 1.15A 4wg0K-2in3A:
undetectable
4wg0L-2in3A:
undetectable
4wg0M-2in3A:
undetectable		 4wg0K-2in3A:
4.78
4wg0L-2in3A:
4.78
4wg0M-2in3A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 8 THR A 205
LEU A 203
ILE A 189
LEU A 199
 None
 0.86A 5g48A-2in3A:
undetectable		 5g48A-2in3A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 4 CYH A  19
PHE A  22
ILE A 172
GLY A 192
 None
None
None
GOL  A 220 (-3.3A)
 1.31A 5hesB-2in3A:
undetectable		 5hesB-2in3A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 7 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.93A 5z84C-2in3A:
undetectable
5z84J-2in3A:
undetectable		 5z84C-2in3A:
22.22
5z84J-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 6 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.95A 5z84P-2in3A:
undetectable
5z84W-2in3A:
undetectable		 5z84P-2in3A:
22.22
5z84W-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 6 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.95A 5z85P-2in3A:
undetectable
5z85W-2in3A:
undetectable		 5z85P-2in3A:
22.22
5z85W-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 6 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.95A 5z86C-2in3A:
undetectable
5z86J-2in3A:
undetectable		 5z86C-2in3A:
22.22
5z86J-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 6 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.98A 5z86P-2in3A:
undetectable
5z86W-2in3A:
undetectable		 5z86P-2in3A:
22.22
5z86W-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 6 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.92A 5zcpC-2in3A:
undetectable
5zcpJ-2in3A:
undetectable		 5zcpC-2in3A:
22.22
5zcpJ-2in3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2in3 HYPOTHETICAL PROTEIN
(Nitrosomonas
europaea) 		4 / 6 GLN A 117
PHE A 120
LEU A 133
PHE A 151
 None
 0.95A 5zcpP-2in3A:
undetectable
5zcpW-2in3A:
undetectable		 5zcpP-2in3A:
22.22
5zcpW-2in3A:
20.59