SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2inp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)
2inp PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 12 PHE A 190
GLY C 142
ALA C 141
SER A 116
GLY A 119
None
1.13A 1igxA-2inpA:
undetectable
1igxA-2inpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
3 / 3 ASP C 209
ASP C  52
LYS C 139
None
1.11A 1lqtB-2inpC:
undetectable
1lqtB-2inpC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
3 / 3 ASP C 209
ASP C  52
LYS C 139
None
1.11A 1lquB-2inpC:
undetectable
1lquB-2inpC:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
5 / 9 ILE C 222
GLY C 224
ALA C 133
GLU C 130
ARG C 160
None
1.32A 1mrgA-2inpC:
undetectable
1mrgA-2inpC:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
5 / 9 ILE C 222
GLY C 224
TYR C 227
ALA C 133
GLU C 130
None
1.27A 1mrgA-2inpC:
undetectable
1mrgA-2inpC:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)
2inp PHENOL HYDROXYLASE
COMPONENT PHO

(Pseudomonas
stutzeri)
3 / 3 PHE E  50
LEU E 104
LEU E  80
None
0.51A 1mx1E-2inpE:
undetectable
1mx1E-2inpE:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.64A 1rjoA-2inpA:
undetectable
1rjoA-2inpA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.58A 1rkyA-2inpA:
undetectable
1rkyA-2inpA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 11 GLU A 138
HIS A 141
GLU A 199
PHE A 207
GLU A 233
FE  A   3 ( 2.5A)
FE  A   3 (-3.4A)
FE  A   1 (-2.2A)
None
FE  A   1 ( 1.8A)
1.02A 1rnrA-2inpA:
16.6
1rnrA-2inpA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 12 GLU A 138
HIS A 141
GLU A 199
PHE A 207
GLU A 233
FE  A   3 ( 2.5A)
FE  A   3 (-3.4A)
FE  A   1 (-2.2A)
None
FE  A   1 ( 1.8A)
1.02A 1rnrB-2inpA:
16.4
1rnrB-2inpA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 8 TRP A 336
THR A 337
CYH A 343
TRP A 351
None
1.34A 1uw6A-2inpA:
undetectable
1uw6B-2inpA:
undetectable
1uw6A-2inpA:
18.38
1uw6B-2inpA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 8 TRP A 336
THR A 337
CYH A 343
TRP A 351
None
1.33A 1uw6D-2inpA:
undetectable
1uw6E-2inpA:
undetectable
1uw6D-2inpA:
18.38
1uw6E-2inpA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 8 TRP A 336
THR A 337
CYH A 343
TRP A 351
None
1.39A 1uw6G-2inpA:
undetectable
1uw6H-2inpA:
undetectable
1uw6G-2inpA:
18.38
1uw6H-2inpA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 8 TRP A 336
THR A 337
CYH A 343
TRP A 351
None
1.38A 1uw6P-2inpA:
undetectable
1uw6Q-2inpA:
undetectable
1uw6P-2inpA:
18.38
1uw6Q-2inpA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 8 TRP A 351
TRP A 336
THR A 337
CYH A 343
None
1.38A 1uw6P-2inpA:
undetectable
1uw6T-2inpA:
undetectable
1uw6P-2inpA:
18.38
1uw6T-2inpA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.69A 1w2zA-2inpA:
undetectable
1w2zA-2inpA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.62A 1w2zB-2inpA:
undetectable
1w2zB-2inpA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.64A 1w2zC-2inpA:
undetectable
1w2zC-2inpA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.63A 1w2zD-2inpA:
undetectable
1w2zD-2inpA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 8 LEU A  72
PHE A  76
LEU A 159
SER A 142
None
0.95A 1wrlC-2inpA:
undetectable
1wrlD-2inpA:
undetectable
1wrlC-2inpA:
11.66
1wrlD-2inpA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 8 LEU A 206
PHE A 190
PHE A 179
SER A 142
None
0.87A 1wrlC-2inpA:
undetectable
1wrlD-2inpA:
undetectable
1wrlC-2inpA:
11.66
1wrlD-2inpA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 9 PHE A 307
LEU A 241
GLY A 240
VAL A 258
ILE A 262
None
1.27A 2a1oB-2inpA:
undetectable
2a1oB-2inpA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
3 / 3 ASP C 159
PHE C 252
ARG C  88
None
0.70A 2a3aA-2inpC:
undetectable
2a3aA-2inpC:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 SER A  89
GLU A 357
ASP A 281
None
0.76A 2avdB-2inpA:
undetectable
2avdB-2inpA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
5 / 10 ALA C 313
LEU C 126
LEU C 300
LEU C 229
LYS C 233
None
1.41A 2ceoB-2inpC:
undetectable
2ceoB-2inpC:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA602_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)
2inp PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 5 HIS A 494
ILE C  13
PRO A 490
ASP A 491
None
1.30A 2f7fA-2inpA:
0.0
2f7fA-2inpA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 6 TRP A 451
PRO A 453
LEU A 395
GLY A 460
None
0.83A 2hs2B-2inpA:
undetectable
2hs2B-2inpA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.65A 2oqeA-2inpA:
undetectable
2oqeA-2inpA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.65A 2oqeB-2inpA:
undetectable
2oqeB-2inpA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.63A 2oqeC-2inpA:
undetectable
2oqeC-2inpA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.66A 2oqeD-2inpA:
undetectable
2oqeD-2inpA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.64A 2oqeF-2inpA:
undetectable
2oqeF-2inpA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
6 / 12 LEU A 139
GLY C 142
ALA C 141
ASN C 137
GLY A 119
ILE C 154
None
1.43A 2qakA-2inpA:
undetectable
2qakA-2inpA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 6 ARG A 120
ARG A 128
PHE A 122
PHE A 188
None
1.29A 2qeiA-2inpA:
undetectable
2qeiA-2inpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
3 / 3 LEU C 131
MET C 135
MET C 253
None
0.98A 2vavF-2inpC:
undetectable
2vavF-2inpC:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.69A 2w0qA-2inpA:
undetectable
2w0qA-2inpA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.68A 2w0qB-2inpA:
undetectable
2w0qB-2inpA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 PHE A 408
SER A 277
LEU A 273
None
0.81A 2w1bA-2inpA:
1.9
2w1bA-2inpA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
4 / 6 ARG C 110
ASP C 245
GLN C 236
GLU C 239
None
1.45A 2ya7C-2inpC:
undetectable
2ya7C-2inpC:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
4 / 8 THR C 115
LEU C 122
ASP C 235
SER C 240
None
0.97A 2zw9A-2inpC:
undetectable
2zw9A-2inpC:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 10 GLY A 119
VAL A 129
ALA A 130
PHE A 122
PHE A 188
None
1.35A 3a3yA-2inpA:
undetectable
3a3yA-2inpA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 12 PHE A 225
THR A 203
PHE A 198
PHE A 179
GLU A 199
None
None
None
None
FE  A   1 (-2.2A)
1.22A 3apxA-2inpA:
undetectable
3apxA-2inpA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 12 LEU A 206
PHE A 178
ALA A 111
ALA A 193
GLY A 269
None
1.12A 3c6gB-2inpA:
undetectable
3c6gB-2inpA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.67A 3hiiA-2inpA:
undetectable
3hiiA-2inpA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 HIS A  85
HIS A 151
HIS A 155
None
0.66A 3hiiB-2inpA:
undetectable
3hiiB-2inpA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 4 GLN A 259
PRO A 256
VAL A 255
GLU A 252
None
1.23A 3huoA-2inpA:
undetectable
3huoA-2inpA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHO

(Pseudomonas
stutzeri)
5 / 12 ALA E  76
TRP E  30
ILE E  98
LEU E  26
THR E 108
None
1.17A 3ql0A-2inpE:
undetectable
3ql0A-2inpE:
22.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)
2inp PHENOL HYDROXYLASE
COMPONENT PHN
PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri;
Pseudomonas
stutzeri)
3 / 3 HIS A 155
HIS A 494
ILE C  13
None
0.45A 3u52A-2inpA:
64.0
3u52C-2inpA:
22.6
3u52A-2inpA:
100.00
3u52C-2inpA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN
PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri;
Pseudomonas
stutzeri)
4 / 5 PHE A  34
LEU C 131
GLY C 132
THR C 205
None
1.07A 3wrkD-2inpA:
undetectable
3wrkD-2inpA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_NCAA1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 7 THR A 346
HIS A 349
ASN A  95
TYR A 171
None
1.49A 4a3uA-2inpA:
undetectable
4a3uA-2inpA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHO

(Pseudomonas
stutzeri)
5 / 12 ALA E  76
TRP E  30
ILE E  98
LEU E  26
THR E 108
None
1.14A 4ej1B-2inpE:
undetectable
4ej1B-2inpE:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 5 VAL A 118
LEU A 191
VAL A 243
PHE A 122
None
1.00A 4lb0B-2inpA:
undetectable
4lb0B-2inpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
5 / 12 VAL C 246
LEU C 126
ILE C 170
ILE C 174
ALA C 181
None
0.93A 4ltwA-2inpC:
undetectable
4ltwA-2inpC:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
4 / 5 ILE C 286
ARG C 320
ASP C 223
GLU C 290
None
1.27A 4nkxD-2inpC:
undetectable
4nkxD-2inpC:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 ASP A  52
TYR A  14
TRP A  50
None
0.90A 4p7nA-2inpA:
undetectable
4p7nA-2inpA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 12 ALA A 193
LEU A 191
GLY A 114
ASP A 180
ALA A 111
None
1.18A 4pclA-2inpA:
undetectable
4pclA-2inpA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
3 / 3 ILE C 163
ASP C 223
ARG C  88
None
0.70A 4pstA-2inpC:
undetectable
4pstA-2inpC:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 12 ILE A 407
THR A 346
VAL A 169
LEU A  99
LEU A 275
None
1.35A 4qztA-2inpA:
undetectable
4qztA-2inpA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 12 ALA A 345
ILE A 477
LEU A 172
MET A 165
GLY A 162
None
1.21A 4r38A-2inpA:
undetectable
4r38A-2inpA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 12 ALA A 345
ILE A 477
LEU A 172
MET A 165
GLY A 162
None
1.17A 4r38C-2inpA:
undetectable
4r38C-2inpA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
5 / 12 ALA A 345
ILE A 477
LEU A 172
MET A 165
GLY A 162
None
1.16A 4r38D-2inpA:
undetectable
4r38D-2inpA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
5 / 12 GLY C 157
TYR C 155
SER C 150
ASP C 159
ASN C 219
None
1.22A 4ymgB-2inpC:
undetectable
4ymgB-2inpC:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
5 / 9 ILE C 222
GLY C 224
ALA C 133
GLU C 130
ARG C 160
None
1.28A 4yp2B-2inpC:
undetectable
4yp2B-2inpC:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 6 LYS A 117
GLY A 114
TYR A 115
ALA A 111
None
1.15A 4yshB-2inpA:
undetectable
4yshB-2inpA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 6 SER A 195
GLU A 199
GLY A 124
GLY A 126
None
FE  A   1 (-2.2A)
None
None
0.98A 5cdpA-2inpA:
undetectable
5cdpB-2inpA:
undetectable
5cdpA-2inpA:
19.96
5cdpB-2inpA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
5 / 9 ILE C 222
GLY C 224
ALA C 133
GLU C 130
ARG C 160
None
1.28A 5cf9B-2inpC:
undetectable
5cf9B-2inpC:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA201_1
(GALNAC/GAL-SPECIFIC
LECTIN)
2inp PHENOL HYDROXYLASE
COMPONENT PHO

(Pseudomonas
stutzeri)
5 / 9 HIS E  33
TYR E 119
GLY E 118
HIS E  65
ASP E  67
None
1.40A 5f8yA-2inpE:
undetectable
5f8yA-2inpE:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
4 / 8 MET C 268
ILE C 286
TYR C 294
LEU C 229
None
0.97A 5ieoA-2inpC:
undetectable
5ieoA-2inpC:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
2inp PHENOL HYDROXYLASE
COMPONENT PHO

(Pseudomonas
stutzeri)
3 / 3 VAL E 106
SER E  68
MET E 114
None
0.94A 5ikqA-2inpE:
undetectable
5ikqA-2inpE:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri)
5 / 12 ARG C 160
ALA C 296
VAL C 129
GLY C 132
ALA C 133
None
0.87A 5jw1B-2inpC:
undetectable
5jw1B-2inpC:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 8 TRP A 336
THR A 337
CYH A 343
TRP A 351
None
1.19A 5kxiD-2inpA:
undetectable
5kxiE-2inpA:
2.4
5kxiD-2inpA:
18.27
5kxiE-2inpA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 7 GLY A 480
ASP A 491
HIS A 160
ASP A 482
None
0.88A 5nnwD-2inpA:
undetectable
5nnwD-2inpA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 7 GLY A 480
ASP A 491
HIS A 160
ASP A 482
None
0.88A 5no9D-2inpA:
undetectable
5no9D-2inpA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 7 THR A 222
PHE A 210
MET A 279
MET A 149
None
1.04A 5u6mA-2inpA:
undetectable
5u6mA-2inpA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 6 ARG A 140
GLN A 146
PHE A  76
LEU A  72
None
1.04A 5z84P-2inpA:
3.5
5z84W-2inpA:
undetectable
5z84P-2inpA:
18.12
5z84W-2inpA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 6 ARG A 140
GLN A 146
PHE A  76
LEU A  72
None
1.04A 5z85P-2inpA:
3.4
5z85W-2inpA:
undetectable
5z85P-2inpA:
18.12
5z85W-2inpA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 6 ARG A 140
GLN A 146
PHE A  76
LEU A  72
None
1.03A 5z86C-2inpA:
2.9
5z86J-2inpA:
undetectable
5z86C-2inpA:
18.12
5z86J-2inpA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 6 ARG A 140
GLN A 146
PHE A  76
LEU A  72
None
1.03A 5z86P-2inpA:
3.5
5z86W-2inpA:
undetectable
5z86P-2inpA:
18.12
5z86W-2inpA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 6 ARG A 140
GLN A 146
PHE A  76
LEU A  72
None
1.03A 5zcoP-2inpA:
2.8
5zcoW-2inpA:
undetectable
5zcoP-2inpA:
18.12
5zcoW-2inpA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 6 ARG A 140
GLN A 146
PHE A  76
LEU A  72
None
0.98A 5zcpC-2inpA:
2.9
5zcpJ-2inpA:
undetectable
5zcpC-2inpA:
18.12
5zcpJ-2inpA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 6 ARG A 140
GLN A 146
PHE A  76
LEU A  72
None
1.00A 5zcpP-2inpA:
3.5
5zcpW-2inpA:
undetectable
5zcpP-2inpA:
18.12
5zcpW-2inpA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
3 / 3 TYR A 377
HIS A 333
MET A 278
None
1.26A 6af6A-2inpA:
1.4
6af6A-2inpA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri)
4 / 7 ILE A 262
GLN A 259
VAL A 258
ILE A 244
None
1.00A 6cduF-2inpA:
2.3
6cduG-2inpA:
2.2
6cduF-2inpA:
19.28
6cduG-2inpA:
19.28