SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2iny'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
3 / 3 ASP A 499
ASP A 898
ASP A 770
None
0.75A 1eizA-2inyA:
undetectable
1eizA-2inyA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 8 PHE A 588
THR A 103
LEU A 584
VAL A  90
None
1.15A 1o76B-2inyA:
undetectable
1o76B-2inyA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 10 VAL A 531
ILE A 107
TYR A 579
ILE A 577
PHE A 292
None
1.36A 1q6iB-2inyA:
undetectable
1q6iB-2inyA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 12 GLY A 184
ALA A 194
ASP A 195
ILE A 174
ILE A 199
None
0.89A 1rl8A-2inyA:
undetectable
1rl8A-2inyA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 12 GLY A 184
ALA A 194
ASP A 195
ILE A 174
ILE A 199
None
0.88A 1rl8B-2inyA:
undetectable
1rl8B-2inyA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 8 ASP A 678
THR A 904
TYR A 907
LEU A 622
None
0.82A 1z2bB-2inyA:
undetectable
1z2bB-2inyA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_C_SAMC803_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 11 GLY A 672
SER A 516
ARG A 515
HIS A 507
TYR A 289
None
1.43A 2h21C-2inyA:
undetectable
2h21C-2inyA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 12 LEU A 311
LEU A 541
MET A 100
LEU A 603
VAL A  92
None
1.19A 2po5A-2inyA:
undetectable
2po5A-2inyA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 11 LEU A 311
LEU A 541
MET A 100
LEU A 603
VAL A  92
None
1.23A 2po5B-2inyA:
undetectable
2po5B-2inyA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 12 MET A 928
LEU A 311
LEU A 541
MET A 100
LEU A 603
None
1.24A 2po7B-2inyA:
undetectable
2po7B-2inyA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 12 LEU A 311
LEU A 541
MET A 100
LEU A 603
VAL A  92
None
1.26A 2qd4B-2inyA:
undetectable
2qd4B-2inyA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 11 GLY A 184
ALA A 194
ASP A 195
ILE A 174
ILE A 199
None
0.88A 2r5qB-2inyA:
undetectable
2r5qB-2inyA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 10 GLY A 184
ALA A 194
ASP A 195
ILE A 174
ILE A 199
None
0.88A 2r5qD-2inyA:
undetectable
2r5qD-2inyA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
3 / 3 ARG A 923
ARG A 604
PRO A 545
None
1.11A 2wljA-2inyA:
undetectable
2wljA-2inyA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 6 SER A 684
SER A 673
GLN A 563
ASP A 857
None
1.36A 2zvjA-2inyA:
undetectable
2zvjA-2inyA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 6 SER A 684
TYR A 763
SER A 673
GLN A 563
None
1.25A 2zvjA-2inyA:
undetectable
2zvjA-2inyA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 12 SER A 441
TYR A 446
ASN A 509
ARG A 113
PHE A 117
None
1.42A 3a27A-2inyA:
undetectable
3a27A-2inyA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
3 / 3 ASP A 499
ASP A 898
ASP A 770
None
0.71A 3douA-2inyA:
undetectable
3douA-2inyA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 8 ALA A 194
ASP A 195
GLY A 186
LEU A 187
VAL A 178
None
1.44A 3em6A-2inyA:
undetectable
3em6A-2inyA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 11 GLY A 184
ALA A 194
ASP A 195
ILE A 174
ILE A 199
None
0.90A 3nu3B-2inyA:
undetectable
3nu3B-2inyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 9 GLY A 184
ALA A 194
ASP A 195
ILE A 174
ILE A 199
None
0.91A 3nujB-2inyA:
undetectable
3nujB-2inyA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 9 GLY A 184
ALA A 194
ASP A 195
ILE A 174
ILE A 199
None
0.90A 3nuoB-2inyA:
undetectable
3nuoB-2inyA:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 12 GLY A 184
ALA A 194
ASP A 195
ILE A 174
ILE A 199
None
0.92A 3pwmA-2inyA:
undetectable
3pwmA-2inyA:
6.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 4 ASP A 195
ASP A 197
GLY A 200
THR A 235
None
1.34A 3tl9B-2inyA:
undetectable
3tl9B-2inyA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 10 GLY A 184
ALA A 194
ASP A 195
ILE A 174
ILE A 199
None
0.97A 3ttpB-2inyA:
undetectable
3ttpB-2inyA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
3 / 3 TYR A 548
MET A 591
LEU A 599
None
0.99A 3vw1D-2inyA:
undetectable
3vw1D-2inyA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_C_T1CC392_1
(TETX2 PROTEIN)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 11 GLN A 775
PHE A 779
GLY A 776
SER A 844
GLY A 839
None
1.43A 4a6nC-2inyA:
0.0
4a6nC-2inyA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 12 TYR A 682
GLY A 679
ASN A 858
LEU A 652
ILE A 297
None
1.08A 4aztA-2inyA:
undetectable
4aztA-2inyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 12 SER A 564
GLY A 567
GLY A 672
LYS A 556
ASP A 569
None
0.89A 4ctkC-2inyA:
undetectable
4ctkC-2inyA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
3 / 3 ASP A 898
ARG A 688
ASP A 499
None
0.86A 4fp9A-2inyA:
undetectable
4fp9A-2inyA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
3 / 3 ASP A 898
ARG A 688
ASP A 499
None
0.73A 4fp9C-2inyA:
undetectable
4fp9C-2inyA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
3 / 3 ASP A 898
ARG A 688
ASP A 499
None
0.70A 4fp9F-2inyA:
undetectable
4fp9F-2inyA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 8 TYR A 217
ARG A 283
ARG A 131
ASP A 445
None
1.04A 4kr4C-2inyA:
undetectable
4kr4C-2inyA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
3 / 3 ASP A 484
ASN A 437
SER A 810
None
0.83A 4obwA-2inyA:
undetectable
4obwA-2inyA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 5 GLN A 334
LEU A 331
SER A 677
ASP A 303
None
1.20A 4qtuD-2inyA:
undetectable
4qtuD-2inyA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
3 / 3 TYR A 851
GLY A 776
PRO A 777
None
0.53A 4qwpA-2inyA:
undetectable
4qwpA-2inyA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 8 ASN A 288
ILE A 290
GLY A 567
THR A 468
None
0.80A 4r20A-2inyA:
undetectable
4r20A-2inyA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 11 GLY A 661
PHE A 668
ASP A 557
TYR A 670
PRO A 658
None
1.46A 4rtrA-2inyA:
undetectable
4rtrA-2inyA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 6 ILE A 107
VAL A 553
THR A  77
ARG A  71
None
1.17A 4xe5A-2inyA:
undetectable
4xe5A-2inyA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 12 SER A 564
GLY A 567
GLY A 672
LYS A 556
ASP A 569
None
0.85A 5ekxA-2inyA:
undetectable
5ekxA-2inyA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 5 SER A 684
SER A 673
GLN A 563
ASP A 857
None
1.39A 5fhrB-2inyA:
undetectable
5fhrB-2inyA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 8 ALA A 444
SER A 441
HIS A 507
HIS A 506
None
1.18A 5km8A-2inyA:
undetectable
5km8B-2inyA:
undetectable
5km8A-2inyA:
8.84
5km8B-2inyA:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
3 / 3 LYS A  64
GLN A 598
ASN A 597
None
1.03A 5l2tA-2inyA:
undetectable
5l2tA-2inyA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_0
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 12 MET A 690
THR A 650
VAL A 906
TYR A 623
GLN A 740
None
1.38A 6ak3A-2inyA:
0.0
6ak3A-2inyA:
6.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
4 / 5 SER A 494
VAL A 363
ASN A 365
PRO A 771
None
1.09A 6fi4A-2inyA:
undetectable
6fi4B-2inyA:
undetectable
6fi4A-2inyA:
14.35
6fi4B-2inyA:
0.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 10 VAL A 531
ILE A 107
TYR A 579
ILE A 577
PHE A 292
None
1.43A 6mkeC-2inyA:
undetectable
6mkeC-2inyA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)
2iny HEXON PROTEIN
(Fowl
aviadenovirus
A)
5 / 10 VAL A 531
ILE A 107
TYR A 579
ILE A 577
PHE A 292
None
1.41A 6mkeD-2inyA:
undetectable
6mkeD-2inyA:
8.11