SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ioj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 2ioj HYPOTHETICAL PROTEIN
AF_1212
(Archaeoglobus
fulgidus) 		5 / 8 ALA A 243
LEU A 265
LEU A 255
LEU A 244
ALA A 268
 None
 1.48A 1e7cA-2iojA:
undetectable		 1e7cA-2iojA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2ioj HYPOTHETICAL PROTEIN
AF_1212
(Archaeoglobus
fulgidus) 		4 / 7 ARG A 313
SER A 312
SER A 316
GLU A 315
 None
 1.22A 2c8aA-2iojA:
undetectable		 2c8aA-2iojA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2ioj HYPOTHETICAL PROTEIN
AF_1212
(Archaeoglobus
fulgidus) 		4 / 6 ARG A 313
SER A 312
SER A 316
GLU A 315
 None
 1.22A 2c8aC-2iojA:
undetectable		 2c8aC-2iojA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2ioj HYPOTHETICAL PROTEIN
AF_1212
(Archaeoglobus
fulgidus) 		5 / 12 THR A 257
LEU A 314
VAL A 209
CYH A 276
VAL A 230
 None
 1.40A 2g72A-2iojA:
undetectable		 2g72A-2iojA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 2ioj HYPOTHETICAL PROTEIN
AF_1212
(Archaeoglobus
fulgidus) 		4 / 9 ILE A 212
ALA A 253
VAL A 230
LYS A 228
 None
 0.86A 2vufB-2iojA:
undetectable		 2vufB-2iojA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2ioj HYPOTHETICAL PROTEIN
AF_1212
(Archaeoglobus
fulgidus) 		4 / 8 ALA A 243
GLY A 258
THR A 307
VAL A 311
 None
 0.82A 4r20A-2iojA:
undetectable		 4r20A-2iojA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 2ioj HYPOTHETICAL PROTEIN
AF_1212
(Archaeoglobus
fulgidus) 		3 / 3 GLU A 231
LYS A 206
ASN A 252
 None
 0.97A 4y1dA-2iojA:
undetectable
4y1dD-2iojA:
undetectable		 4y1dA-2iojA:
19.66
4y1dD-2iojA:
10.42