SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2iqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 2iqi HYPOTHETICAL PROTEIN
XCC0632
(Xanthomonas
campestris) 		3 / 3 ALA A 169
VAL A 168
GLN A 190
 None
 0.66A 3of4B-2iqiA:
undetectable		 3of4B-2iqiA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 2iqi HYPOTHETICAL PROTEIN
XCC0632
(Xanthomonas
campestris) 		5 / 9 VAL A 168
ILE A  70
VAL A 180
ALA A 181
ALA A 187
 None
 1.11A 4oqrA-2iqiA:
undetectable		 4oqrA-2iqiA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 2iqi HYPOTHETICAL PROTEIN
XCC0632
(Xanthomonas
campestris) 		4 / 7 LEU A  54
ALA A 150
LEU A 153
ILE A 127
 None
 0.79A 4ubsA-2iqiA:
undetectable		 4ubsA-2iqiA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2iqi HYPOTHETICAL PROTEIN
XCC0632
(Xanthomonas
campestris) 		4 / 7 TYR A 123
PHE A 103
ILE A 109
GLY A 197
 None
 0.92A 4ze3A-2iqiA:
undetectable		 4ze3A-2iqiA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2iqi HYPOTHETICAL PROTEIN
XCC0632
(Xanthomonas
campestris) 		4 / 8 TYR A 123
PHE A 103
ILE A 109
GLY A 197
 None
 0.91A 5esjA-2iqiA:
undetectable		 5esjA-2iqiA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2iqi HYPOTHETICAL PROTEIN
XCC0632
(Xanthomonas
campestris) 		3 / 3 ALA A 150
ASN A 149
LEU A 148
 None
 0.44A 5i1oA-2iqiA:
undetectable		 5i1oA-2iqiA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2iqi HYPOTHETICAL PROTEIN
XCC0632
(Xanthomonas
campestris) 		3 / 3 ALA A 150
ASN A 149
LEU A 148
 None
 0.43A 5i1pD-2iqiA:
undetectable		 5i1pD-2iqiA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2iqi HYPOTHETICAL PROTEIN
XCC0632
(Xanthomonas
campestris) 		3 / 3 ILE A  65
VAL A 129
PRO A  59
 None
 0.68A 5uunA-2iqiA:
undetectable		 5uunA-2iqiA:
22.18