SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2it0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 2it0 IRON-DEPENDENT
REPRESSOR IDER
(Mycobacterium
tuberculosis) 		4 / 6 ASP A  88
VAL A  87
PRO A 123
THR A 125
 None
 1.40A 2q6oB-2it0A:
undetectable		 2q6oB-2it0A:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 2it0 IRON-DEPENDENT
REPRESSOR IDER
(Mycobacterium
tuberculosis) 		3 / 3 ARG A  80
ILE A 132
SER A 126
 ACT  A2001 ( 4.7A)
None
ACT  A2001 ( 4.5A)
 0.82A 5zw2A-2it0A:
undetectable		 5zw2A-2it0A:
20.40