SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2iu4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 7 VAL A 257
GLY A 259
THR A 263
ILE A 303
 None
 0.74A 1gtnC-2iu4A:
undetectable
1gtnD-2iu4A:
undetectable		 1gtnC-2iu4A:
15.17
1gtnD-2iu4A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 4 LEU A 108
ILE A  88
ARG A  89
TYR A 127
 None
 1.24A 1rk3A-2iu4A:
0.0		 1rk3A-2iu4A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 4 GLY A 186
SER A 135
VAL A 148
LEU A 260
 None
 1.19A 1yajB-2iu4A:
2.4		 1yajB-2iu4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 ALA A  57
LEU A  67
ALA A  70
ILE A 182
LEU A 256
 None
 1.00A 2aclA-2iu4A:
undetectable
2aclE-2iu4A:
undetectable		 2aclA-2iu4A:
24.26
2aclE-2iu4A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 5 LEU A 108
ILE A  88
ARG A  89
TYR A 127
 None
 1.26A 2zlcA-2iu4A:
undetectable		 2zlcA-2iu4A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 213
GLY A 259
GLY A 302
GLY A 186
THR A 263
 SO4  A1370 (-3.5A)
None
None
None
None
 1.08A 3eluA-2iu4A:
undetectable		 3eluA-2iu4A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 213
GLY A 259
GLY A 302
GLY A 186
THR A 263
 SO4  A1370 (-3.5A)
None
None
None
None
 1.06A 3embA-2iu4A:
undetectable		 3embA-2iu4A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 11 ILE A  88
VAL A  97
PHE A  98
VAL A 125
ILE A  46
 None
None
None
None
SO4  A1373 (-4.5A)
 1.09A 3rf4A-2iu4A:
undetectable
3rf4C-2iu4A:
undetectable		 3rf4A-2iu4A:
16.67
3rf4C-2iu4A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 11 ILE A  46
ILE A  88
VAL A  97
PHE A  98
VAL A 125
 SO4  A1373 (-4.5A)
None
None
None
None
 1.12A 3rf4A-2iu4A:
undetectable
3rf4B-2iu4A:
undetectable		 3rf4A-2iu4A:
16.67
3rf4B-2iu4A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 11 ILE A  46
ILE A  88
VAL A  97
PHE A  98
VAL A 125
 SO4  A1373 (-4.5A)
None
None
None
None
 1.09A 3rf4B-2iu4A:
undetectable
3rf4C-2iu4A:
undetectable		 3rf4B-2iu4A:
16.67
3rf4C-2iu4A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		3 / 3 ASN A 250
ALA A 249
LYS A 251
 None
 0.80A 3runA-2iu4A:
undetectable		 3runA-2iu4A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		6 / 12 LEU A  25
LEU A  34
ILE A  18
MET A  14
VAL A  62
GLY A 292
 None
 1.39A 4an2A-2iu4A:
undetectable		 4an2A-2iu4A:
26.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 PHE A 288
VAL A 310
GLU A 164
THR A 323
GLY A  65
 None
None
None
None
SO4  A1373 (-3.9A)
 1.16A 4hvcA-2iu4A:
undetectable		 4hvcA-2iu4A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 PHE A 288
VAL A 310
GLU A 164
THR A 323
GLY A  65
 None
None
None
None
SO4  A1373 (-3.9A)
 1.17A 4hvcB-2iu4A:
undetectable		 4hvcB-2iu4A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 259
GLY A 261
ILE A 231
GLY A 186
LEU A 235
 None
 1.03A 4n48A-2iu4A:
undetectable		 4n48A-2iu4A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 259
GLY A 261
ILE A 231
GLY A 186
LEU A 235
 None
 1.00A 4n48B-2iu4A:
undetectable		 4n48B-2iu4A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 6 ASP A 206
GLU A 223
VAL A 187
ALA A 188
 None
 1.00A 4nkxA-2iu4A:
undetectable		 4nkxA-2iu4A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 PHE A 288
VAL A 310
GLU A 164
THR A 323
GLY A  65
 None
None
None
None
SO4  A1373 (-3.9A)
 1.23A 4olfA-2iu4A:
undetectable		 4olfA-2iu4A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 5 ILE A 115
HIS A 155
TYR A  39
VAL A  91
 None
 1.35A 4s0vA-2iu4A:
undetectable		 4s0vA-2iu4A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 4 ALA A 327
VAL A  62
GLY A  65
THR A 323
 None
None
SO4  A1373 (-3.9A)
None
 1.01A 4ubeA-2iu4A:
2.5		 4ubeA-2iu4A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 LEU A 203
GLY A 302
GLY A 261
LEU A 268
GLU A 267
 None
 1.19A 4x61A-2iu4A:
2.1		 4x61A-2iu4A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 7 ILE A  10
GLU A  55
GLY A  51
GLY A  73
 None
None
HIQ  A 215 ( 3.1A)
None
 0.74A 5a06A-2iu4A:
2.9		 5a06A-2iu4A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 7 ILE A  10
GLU A  55
GLY A  51
GLY A  73
 None
None
HIQ  A 215 ( 3.1A)
None
 0.77A 5a06B-2iu4A:
2.9		 5a06B-2iu4A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 7 ILE A  10
GLU A  55
GLY A  51
GLY A  73
 None
None
HIQ  A 215 ( 3.1A)
None
 0.75A 5a06C-2iu4A:
2.9		 5a06C-2iu4A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 7 ILE A  10
GLU A  55
GLY A  51
GLY A  73
 None
None
HIQ  A 215 ( 3.1A)
None
 0.76A 5a06E-2iu4A:
2.9		 5a06E-2iu4A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 7 ILE A  10
GLU A  55
GLY A  51
GLY A  73
 None
None
HIQ  A 215 ( 3.1A)
None
 0.74A 5a06F-2iu4A:
undetectable		 5a06F-2iu4A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 324
GLY A  60
THR A 323
HIS A 331
GLU A 330
 None
 0.82A 5ekxB-2iu4A:
undetectable		 5ekxB-2iu4A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		4 / 5 LEU A 307
LYS A 240
LEU A 279
GLU A 282
 None
 1.15A 5weaA-2iu4A:
3.4		 5weaA-2iu4A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 324
GLY A  60
THR A 323
HIS A 331
GLU A 330
 None
 0.94A 5wz1A-2iu4A:
undetectable		 5wz1A-2iu4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 324
GLY A  60
THR A 323
HIS A 331
GLU A 330
 None
 0.92A 5wz1C-2iu4A:
undetectable		 5wz1C-2iu4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 324
GLY A  60
THR A 323
HIS A 331
GLU A 330
 None
 0.96A 5wz1D-2iu4A:
undetectable		 5wz1D-2iu4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 324
GLY A  60
THR A 323
HIS A 331
GLU A 330
 None
 0.89A 5wz1E-2iu4A:
undetectable		 5wz1E-2iu4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 324
GLY A  60
THR A 323
HIS A 331
GLU A 330
 None
 0.95A 5wz1F-2iu4A:
undetectable		 5wz1F-2iu4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 324
GLY A  60
THR A 323
HIS A 331
GLU A 330
 None
 0.94A 5wz1G-2iu4A:
undetectable		 5wz1G-2iu4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 324
GLY A  60
THR A 323
HIS A 331
GLU A 330
 None
 0.92A 5wz1H-2iu4A:
undetectable		 5wz1H-2iu4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 PHE A 288
VAL A 310
GLU A 164
THR A 323
GLY A  65
 None
None
None
None
SO4  A1373 (-3.9A)
 1.31A 5xioA-2iu4A:
undetectable		 5xioA-2iu4A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 GLY A 259
GLY A 302
ASN A 293
SER A 297
MET A 300
 None
None
None
HIQ  A 215 ( 3.8A)
None
 1.35A 5yf0A-2iu4A:
undetectable		 5yf0A-2iu4A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 9 LEU A 185
THR A 184
ASP A 133
ILE A 303
ILE A 212
 None
 1.02A 6ebpA-2iu4A:
undetectable		 6ebpA-2iu4A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 9 LEU A 305
GLY A 211
ILE A 212
PHE A 271
ILE A 231
 None
 1.09A 6ebpA-2iu4A:
undetectable		 6ebpA-2iu4A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 10 LEU A 305
GLY A 211
ILE A 212
PHE A 271
ILE A 231
 None
 1.11A 6ebpB-2iu4A:
undetectable		 6ebpB-2iu4A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 10 LEU A 185
THR A 184
ASP A 133
ILE A 303
ILE A 212
 None
 1.03A 6ebpC-2iu4A:
undetectable		 6ebpC-2iu4A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 10 LEU A 305
GLY A 211
ILE A 212
PHE A 271
ILE A 231
 None
 1.12A 6ebpC-2iu4A:
undetectable		 6ebpC-2iu4A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 11 LEU A 185
THR A 184
ASP A 133
ILE A 303
ILE A 212
 None
 1.02A 6ebzC-2iu4A:
undetectable		 6ebzC-2iu4A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 2iu4 DIHYDROXYACETONE
KINASE
(Lactococcus
lactis) 		5 / 12 PHE A 288
VAL A 310
GLU A 164
THR A 323
GLY A  65
 None
None
None
None
SO4  A1373 (-3.9A)
 1.17A 6mn8A-2iu4A:
undetectable		 6mn8A-2iu4A:
21.22