SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2iuj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 5 HIS A 261
LEU A 329
LEU A 560
GLY A 271
 None
 1.12A 1a4lB-2iujA:
undetectable		 1a4lB-2iujA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 5 GLU A 766
TYR A 340
TYR A 712
PHE A 330
 None
 1.50A 1dfoB-2iujA:
undetectable		 1dfoB-2iujA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 5 GLU A 766
TYR A 340
TYR A 712
PHE A 330
 None
 1.50A 1dfoD-2iujA:
undetectable		 1dfoD-2iujA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 5 GLU A 766
TYR A 340
TYR A 712
PHE A 330
 None
 1.50A 1dfoC-2iujA:
undetectable		 1dfoC-2iujA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 6 ASN A 503
ILE A 429
ASN A 436
THR A 442
 None
 1.27A 1h7xA-2iujA:
undetectable		 1h7xA-2iujA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 6 ASN A 503
ILE A 429
ASN A 436
THR A 442
 None
 1.27A 1h7xB-2iujA:
undetectable		 1h7xB-2iujA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 6 ASN A 503
ILE A 429
ASN A 436
THR A 442
 None
 1.27A 1h7xC-2iujA:
undetectable		 1h7xC-2iujA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 6 ASN A 503
ILE A 429
ASN A 436
THR A 442
 None
 1.27A 1h7xD-2iujA:
undetectable		 1h7xD-2iujA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 7 SER A 852
ASP A 548
GLU A 775
GLU A 840
 None
 1.16A 1knyA-2iujA:
0.8
1knyB-2iujA:
1.0		 1knyA-2iujA:
14.82
1knyB-2iujA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 6 MET A 829
ALA A 827
GLU A 358
GLU A 362
 None
 1.48A 1qhyA-2iujA:
undetectable		 1qhyA-2iujA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 LYS A 755
ILE A 752
THR A 439
 None
 0.75A 1rx3A-2iujA:
undetectable		 1rx3A-2iujA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 THR A 788
GLU A 167
HIS A 536
 None
 0.85A 1xwfA-2iujA:
undetectable		 1xwfA-2iujA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 THR A 788
GLU A 167
HIS A 536
 None
 0.89A 1xwfB-2iujA:
undetectable		 1xwfB-2iujA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 THR A 788
GLU A 167
HIS A 536
 None
 0.90A 1xwfC-2iujA:
undetectable		 1xwfC-2iujA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 THR A 788
GLU A 167
HIS A 536
 None
 0.87A 1xwfD-2iujA:
undetectable		 1xwfD-2iujA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 THR A 788
PRO A 537
TYR A 642
 None
 0.96A 2dxrA-2iujA:
undetectable		 2dxrA-2iujA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 7 LEU A 312
GLN A 336
PHE A 337
PHE A 287
 None
 1.01A 2eijP-2iujA:
undetectable
2eijW-2iujA:
undetectable		 2eijP-2iujA:
14.45
2eijW-2iujA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 GLY A 715
LEU A 717
ASP A 761
LEU A 768
SER A 769
 None
 1.35A 2nv4A-2iujA:
undetectable		 2nv4A-2iujA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 GLY A 715
LEU A 717
ASP A 761
LEU A 768
SER A 769
 None
 1.35A 2nv4B-2iujA:
undetectable		 2nv4B-2iujA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 6 TYR A 306
TYR A 712
GLN A 711
ILE A 765
 None
 1.37A 2pgzD-2iujA:
undetectable
2pgzE-2iujA:
undetectable		 2pgzD-2iujA:
13.60
2pgzE-2iujA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 PRO A 830
ASN A 815
ARG A 823
 None
 1.04A 2qeuB-2iujA:
undetectable		 2qeuB-2iujA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 9 ARG A 557
LEU A 768
ILE A 552
ALA A 269
GLY A 565
 None
 1.01A 2v0mB-2iujA:
undetectable		 2v0mB-2iujA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 ALA A  97
GLY A  81
LEU A 128
ASN A  78
PHE A  99
 None
 0.97A 2y7hB-2iujA:
undetectable		 2y7hB-2iujA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 ALA A  97
GLY A  81
LEU A 128
ASN A  78
PHE A  99
 None
 0.97A 2y7hC-2iujA:
undetectable		 2y7hC-2iujA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 11 THR A 570
ILE A 718
LEU A 762
ILE A 765
VAL A 345
 None
 1.21A 3a51A-2iujA:
undetectable		 3a51A-2iujA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 THR A 570
ILE A 718
LEU A 762
ILE A 765
VAL A 345
 None
 1.25A 3a51D-2iujA:
undetectable		 3a51D-2iujA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 7 LEU A  60
GLN A  59
PHE A  99
LEU A 128
 None
 1.04A 3ag2C-2iujA:
undetectable		 3ag2C-2iujA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 TRP A 698
TRP A 588
PHE A 590
VAL A 520
 None
 1.00A 3b3pA-2iujA:
undetectable
3b3pB-2iujA:
2.2		 3b3pA-2iujA:
20.18
3b3pB-2iujA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 5 LEU A 653
GLN A 681
HIS A 536
LEU A 532
 None
 1.20A 3ce6D-2iujA:
undetectable		 3ce6D-2iujA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GVU_A_STIA1001_2
(TYROSINE-PROTEIN
KINASE ABL2)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 5 VAL A 371
ILE A 364
TYR A 824
MET A 829
 None
 1.39A 3gvuA-2iujA:
undetectable		 3gvuA-2iujA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 LYS A 558
ILE A 767
GLY A 271
ALA A 276
VAL A 275
 None
 1.08A 3jb3A-2iujA:
undetectable		 3jb3A-2iujA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 SER A 512
ASN A 368
GLN A 711
ASN A 516
 None
 1.19A 3n62A-2iujA:
undetectable		 3n62A-2iujA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 SER A 512
ASN A 368
GLN A 711
ASN A 516
 None
 1.24A 3n66B-2iujA:
undetectable		 3n66B-2iujA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_C_ACTC510_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 5 ARG A 232
THR A 233
ASP A 201
GLU A 245
 None
 1.30A 3v5vC-2iujA:
0.0
3v5vD-2iujA:
0.0		 3v5vC-2iujA:
20.07
3v5vD-2iujA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 GLN A 509
HIS A 513
HIS A 704
HIS A 518
 None
FE  A1854 (-3.5A)
FE  A1854 (-3.5A)
FE  A1854 (-3.4A)
 0.78A 3w6hA-2iujA:
undetectable		 3w6hA-2iujA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 7 LEU A  60
GLN A  59
PHE A  99
LEU A 128
 None
 0.96A 3x2qP-2iujA:
undetectable
3x2qW-2iujA:
undetectable		 3x2qP-2iujA:
14.45
3x2qW-2iujA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 PRO A 132
LEU A  60
ILE A 107
ILE A  11
PHE A 111
 None
 1.26A 4a79A-2iujA:
undetectable		 4a79A-2iujA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 PRO A 132
LEU A  60
ILE A 107
ILE A  11
PHE A 111
 None
 1.29A 4a79B-2iujA:
undetectable		 4a79B-2iujA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 TRP A 588
TRP A 679
THR A 591
 None
 1.47A 4bboB-2iujA:
undetectable		 4bboB-2iujA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 SER A 577
ILE A 510
PHE A 571
GLU A 568
 None
 1.18A 4cx7A-2iujA:
undetectable
4cx7B-2iujA:
undetectable		 4cx7A-2iujA:
20.10
4cx7B-2iujA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 SER A 577
ILE A 510
TRP A 514
GLU A 568
 None
 0.83A 4cx7A-2iujA:
undetectable
4cx7B-2iujA:
undetectable		 4cx7A-2iujA:
20.10
4cx7B-2iujA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 SER A 577
ILE A 510
PHE A 571
GLU A 568
 None
 1.14A 4cx7C-2iujA:
undetectable
4cx7D-2iujA:
undetectable		 4cx7C-2iujA:
20.10
4cx7D-2iujA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 SER A 577
ILE A 510
TRP A 514
GLU A 568
 None
 0.87A 4cx7C-2iujA:
undetectable
4cx7D-2iujA:
undetectable		 4cx7C-2iujA:
20.10
4cx7D-2iujA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 4 LEU A 842
ILE A 853
GLY A 841
PHE A 709
 None
 0.92A 4dc3A-2iujA:
undetectable		 4dc3A-2iujA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 10 PHE A 296
LEU A 305
VAL A 310
LEU A 762
THR A 763
 None
 0.92A 4e3hA-2iujA:
undetectable		 4e3hA-2iujA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_B_ACTB502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 5 GLU A 245
ARG A 232
THR A 233
ASP A 201
 None
 1.33A 4e7cA-2iujA:
0.0
4e7cB-2iujA:
0.0		 4e7cA-2iujA:
20.07
4e7cB-2iujA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_D_VK3D202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 5 TRP A 698
ARG A 602
TYR A 624
TYR A 622
 None
 1.33A 4f8yC-2iujA:
undetectable
4f8yD-2iujA:
undetectable		 4f8yC-2iujA:
12.43
4f8yD-2iujA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 9 GLY A 670
PRO A 228
TYR A 585
GLY A 221
TYR A 203
 None
 1.29A 4fimA-2iujA:
undetectable		 4fimA-2iujA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 ASP A 205
ARG A 557
ASP A 208
 None
 0.86A 4fp9A-2iujA:
undetectable		 4fp9A-2iujA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 ASP A 205
ARG A 557
ASP A 208
 None
 0.90A 4fp9C-2iujA:
undetectable		 4fp9C-2iujA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 ASP A 621
ARG A 823
ASP A 454
 None
 0.89A 4fp9C-2iujA:
undetectable		 4fp9C-2iujA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 ASP A 205
ARG A 557
ASP A 208
 None
 0.87A 4fp9F-2iujA:
undetectable		 4fp9F-2iujA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 LYS A 755
ILE A 752
THR A 439
 None
 0.81A 4gh8A-2iujA:
undetectable		 4gh8A-2iujA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 7 SER A 512
ASN A 368
GLN A 711
ASN A 516
 None
 1.22A 4kcnB-2iujA:
0.6		 4kcnB-2iujA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 11 HIS A 771
PRO A 848
HIS A 508
PHE A 709
HIS A 513
 None
None
None
None
FE  A1854 (-3.5A)
 1.27A 4lxzB-2iujA:
undetectable		 4lxzB-2iujA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 GLN A 509
HIS A 513
HIS A 704
HIS A 518
 None
FE  A1854 (-3.5A)
FE  A1854 (-3.5A)
FE  A1854 (-3.4A)
 0.80A 4n16A-2iujA:
undetectable		 4n16A-2iujA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 ILE A 567
GLN A 509
HIS A 513
HIS A 704
 None
None
FE  A1854 (-3.5A)
FE  A1854 (-3.5A)
 0.90A 4n16A-2iujA:
undetectable		 4n16A-2iujA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 10 LEU A 696
LEU A 542
ILE A 538
LEU A 541
LEU A 653
 None
 0.95A 4odoA-2iujA:
undetectable		 4odoA-2iujA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 10 LEU A 696
LEU A 542
ILE A 538
LEU A 541
LEU A 653
 None
 1.00A 4odoC-2iujA:
2.2		 4odoC-2iujA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 ILE A 697
VAL A 667
GLN A 660
LEU A 659
LEU A 689
 None
 1.44A 4qztA-2iujA:
0.3		 4qztA-2iujA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 THR A 751
GLU A 731
LEU A 464
PHE A 728
 None
 0.92A 4r38B-2iujA:
undetectable		 4r38B-2iujA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 9 THR A 751
GLU A 731
LEU A 464
ILE A 462
PHE A 728
 None
 1.17A 4r38C-2iujA:
undetectable		 4r38C-2iujA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 LEU A 794
GLY A 792
GLU A 795
GLU A 641
 None
 0.80A 4rjdA-2iujA:
undetectable
4rjdB-2iujA:
undetectable		 4rjdA-2iujA:
5.82
4rjdB-2iujA:
5.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 SER A 512
TYR A 507
ASP A 598
 None
 0.85A 4rp8C-2iujA:
undetectable		 4rp8C-2iujA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 ASN A  21
PHE A 121
TYR A 146
 None
 0.85A 4u15A-2iujA:
undetectable		 4u15A-2iujA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 7 LEU A  60
GLN A  59
PHE A  99
LEU A 128
 None
 0.94A 5b1aP-2iujA:
undetectable
5b1aW-2iujA:
undetectable		 5b1aP-2iujA:
14.45
5b1aW-2iujA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 7 LEU A  60
GLN A  59
PHE A  99
LEU A 128
 None
 0.97A 5b3sC-2iujA:
undetectable
5b3sJ-2iujA:
undetectable		 5b3sC-2iujA:
14.45
5b3sJ-2iujA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 7 LEU A  60
GLN A  59
PHE A  99
LEU A 128
 None
 0.98A 5b3sP-2iujA:
undetectable		 5b3sP-2iujA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		3 / 3 ASP A 199
ASN A 529
PHE A 524
 None
 0.55A 5dsgB-2iujA:
undetectable		 5dsgB-2iujA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 HIS A 771
PRO A 848
HIS A 508
PHE A 709
HIS A 513
 None
None
None
None
FE  A1854 (-3.5A)
 1.37A 5eenB-2iujA:
undetectable		 5eenB-2iujA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 10 ILE A 326
LEU A 329
ILE A 764
LEU A 768
LEU A 338
 None
 1.12A 5ienB-2iujA:
undetectable		 5ienB-2iujA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 7 LEU A  60
GLN A  59
PHE A  99
LEU A 128
 None
 0.95A 5iy5C-2iujA:
undetectable
5iy5J-2iujA:
undetectable		 5iy5C-2iujA:
14.42
5iy5J-2iujA:
6.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 VAL A 480
GLU A 463
HIS A 400
ALA A 461
LEU A 380
 None
 1.16A 5nd4B-2iujA:
undetectable		 5nd4B-2iujA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		5 / 12 VAL A 480
GLU A 463
LEU A 460
ALA A 461
LEU A 380
 None
 1.23A 5nd4B-2iujA:
undetectable		 5nd4B-2iujA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 SER A 512
ASN A 368
GLN A 711
ASN A 516
 None
 1.25A 5vunA-2iujA:
undetectable		 5vunA-2iujA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 SER A 512
ASN A 368
GLN A 711
ASN A 516
 None
 1.25A 5vunB-2iujA:
undetectable		 5vunB-2iujA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 SER A 512
ASN A 368
GLN A 711
ASN A 516
 None
 1.23A 5vuoB-2iujA:
undetectable		 5vuoB-2iujA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2iuj LIPOXYGENASE L-5
(Glycine
max) 		4 / 8 SER A 512
ASN A 368
GLN A 711
ASN A 516
 None
 1.25A 6auuB-2iujA:
undetectable		 6auuB-2iujA:
20.18