SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2iun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		5 / 12 ILE A 653
ALA A 614
LEU A 595
LEU A 671
ILE A 600
 None
 1.29A 1g5yB-2iunA:
undetectable		 1g5yB-2iunA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		4 / 8 THR A 781
PRO A 782
LEU A 755
PHE A 757
 None
 0.75A 1h4oG-2iunA:
undetectable		 1h4oG-2iunA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		3 / 3 ALA A 602
VAL A 654
TRP A 670
 None
 0.93A 1jo3A-2iunA:
undetectable		 1jo3A-2iunA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		4 / 7 THR A 781
PRO A 782
LEU A 755
PHE A 757
 None
 0.68A 2vl2B-2iunA:
undetectable		 2vl2B-2iunA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		3 / 3 ASN A 666
LEU A 699
PHE A 601
 None
 0.78A 4dajB-2iunA:
undetectable		 4dajB-2iunA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		3 / 3 VAL A 645
GLY A 648
LYS A 760
 None
 0.61A 4k50A-2iunA:
undetectable		 4k50A-2iunA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		3 / 3 VAL A 645
GLY A 648
LYS A 760
 None
 0.66A 4k50E-2iunA:
undetectable		 4k50E-2iunA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		4 / 7 LEU A 759
THR A 781
ILE A 784
GLY A 756
 None
 0.92A 4l39B-2iunA:
undetectable		 4l39B-2iunA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		5 / 12 PRO A 723
PHE A 768
THR A 766
SER A 644
GLY A 765
 None
 1.47A 4olfA-2iunA:
undetectable		 4olfA-2iunA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		5 / 10 ALA A 586
THR A 587
ALA A 620
GLY A 679
ALA A 680
 None
 1.06A 4qw1Y-2iunA:
undetectable
4qw1Z-2iunA:
undetectable		 4qw1Y-2iunA:
19.62
4qw1Z-2iunA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		5 / 10 ALA A 586
THR A 587
ALA A 620
GLY A 679
ALA A 680
 None
 1.06A 4qw3K-2iunA:
undetectable
4qw3L-2iunA:
undetectable		 4qw3K-2iunA:
21.89
4qw3L-2iunA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		5 / 10 ALA A 586
THR A 587
ALA A 620
GLY A 679
ALA A 680
 None
 1.06A 4qw3Y-2iunA:
undetectable
4qw3Z-2iunA:
undetectable		 4qw3Y-2iunA:
21.89
4qw3Z-2iunA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		5 / 9 ALA A 586
THR A 587
ALA A 620
GLY A 679
ALA A 680
 None
 1.07A 5d0xK-2iunA:
undetectable
5d0xL-2iunA:
undetectable		 5d0xK-2iunA:
23.14
5d0xL-2iunA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		5 / 9 ALA A 586
THR A 587
ALA A 620
GLY A 679
ALA A 680
 None
 1.07A 5d0xY-2iunA:
undetectable
5d0xZ-2iunA:
undetectable		 5d0xY-2iunA:
23.14
5d0xZ-2iunA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		4 / 8 ILE A 653
PRO A 723
THR A 781
PHE A 779
 None
 1.17A 5x23A-2iunA:
undetectable		 5x23A-2iunA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		4 / 8 PRO A 657
THR A 681
THR A 682
TYR A 588
 None
 1.33A 5x2sI-2iunA:
undetectable
5x2sJ-2iunA:
undetectable
5x2sK-2iunA:
undetectable		 5x2sI-2iunA:
22.18
5x2sJ-2iunA:
21.57
5x2sK-2iunA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		4 / 8 PRO A 657
THR A 681
TYR A 588
PRO A 689
 None
 1.15A 5x2sI-2iunA:
undetectable
5x2sJ-2iunA:
undetectable
5x2sK-2iunA:
undetectable		 5x2sI-2iunA:
22.18
5x2sJ-2iunA:
21.57
5x2sK-2iunA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 2iun AVIAN ADENOVIRUS
CELO LONG FIBRE
(Fowl
aviadenovirus
A) 		4 / 7 ILE A 719
VAL A 655
LEU A 755
LEU A 618
 None
 0.73A 6g9bA-2iunA:
undetectable
6g9bB-2iunA:
undetectable		 6g9bA-2iunA:
16.06
6g9bB-2iunA:
15.55