SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2iuy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 6 LEU A  63
ASP A 100
MET A  50
LEU A  75
 None
 1.17A 1errB-2iuyA:
undetectable		 1errB-2iuyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 10 LEU A  63
VAL A  95
VAL A  60
PRO A 112
LEU A  90
 None
 1.24A 1sv5A-2iuyA:
undetectable		 1sv5A-2iuyA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 GLY A 114
VAL A 339
VAL A  16
ALA A  17
LEU A  53
 None
 0.95A 1vptA-2iuyA:
2.5		 1vptA-2iuyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 SER A 269
VAL A 273
TYR A 162
ASN A  48
VAL A 157
 None
 1.18A 1x70B-2iuyA:
4.2		 1x70B-2iuyA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		3 / 3 TRP A  44
GLU A 270
TYR A 162
 None
 1.05A 2a3aA-2iuyA:
undetectable		 2a3aA-2iuyA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 5 LEU A  63
ASP A 100
MET A  50
LEU A  75
 None
 1.23A 2jfaA-2iuyA:
undetectable		 2jfaA-2iuyA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 5 LEU A  63
ASP A 100
MET A  50
LEU A  75
 None
 1.19A 2qxsA-2iuyA:
undetectable		 2qxsA-2iuyA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 5 LEU A  63
ASP A 100
MET A  50
LEU A  75
 None
 1.19A 2qxsB-2iuyA:
undetectable		 2qxsB-2iuyA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		3 / 3 TYR A 212
GLU A 189
ASN A 283
 None
 1.02A 2y7hC-2iuyA:
undetectable		 2y7hC-2iuyA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 SER A 269
VAL A 273
TYR A 162
ASN A  48
VAL A 157
 None
 1.11A 3bjmA-2iuyA:
undetectable		 3bjmA-2iuyA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 SER A 269
VAL A 273
TYR A 162
ASN A  48
VAL A 157
 None
 1.12A 3bjmB-2iuyA:
4.3		 3bjmB-2iuyA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 9 VAL A 278
VAL A 279
GLY A 294
PRO A 316
GLY A 275
 None
 1.27A 3bjwG-2iuyA:
undetectable		 3bjwG-2iuyA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		6 / 12 LEU A 188
PHE A 303
VAL A 297
GLY A 300
GLU A 189
THR A 223
 None
 1.39A 3c6gB-2iuyA:
undetectable		 3c6gB-2iuyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 LEU A  63
LEU A  18
ALA A  17
PRO A 112
THR A 115
 None
 1.12A 3cwkA-2iuyA:
undetectable		 3cwkA-2iuyA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 PHE A 303
VAL A 297
GLU A 189
ILE A 216
THR A 223
 None
 1.19A 3dl9A-2iuyA:
undetectable		 3dl9A-2iuyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 SER A 269
VAL A 273
TYR A 162
ASN A  48
VAL A 157
 None
 1.12A 3g0bB-2iuyA:
undetectable		 3g0bB-2iuyA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 4 ARG A 199
ASP A 302
GLY A 298
THR A 311
 None
 1.11A 3k4vB-2iuyA:
undetectable		 3k4vB-2iuyA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		3 / 3 ARG A  91
VAL A  95
THR A 115
 None
 0.85A 3pwrA-2iuyA:
undetectable		 3pwrA-2iuyA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 LEU A  62
VAL A  60
ALA A  47
ASN A  48
LEU A  49
 None
 0.83A 3r9cA-2iuyA:
undetectable		 3r9cA-2iuyA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		6 / 12 GLN A 250
GLY A 186
GLY A 280
ALA A 247
ALA A 265
SER A 137
 None
 1.38A 3sudA-2iuyA:
undetectable		 3sudA-2iuyA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 8 THR A 125
PRO A 127
GLY A 104
SER A 119
 None
 0.92A 3tzfB-2iuyA:
undetectable		 3tzfB-2iuyA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 8 LEU A  53
VAL A  97
TYR A 338
LEU A  18
 None
 1.04A 3v81C-2iuyA:
undetectable		 3v81C-2iuyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 SER A 269
VAL A 273
TYR A 162
ASN A  48
VAL A 157
 None
 1.06A 3w2tA-2iuyA:
undetectable		 3w2tA-2iuyA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 SER A 269
VAL A 273
TYR A 162
ASN A  48
VAL A 157
 None
 1.09A 3w2tB-2iuyA:
undetectable		 3w2tB-2iuyA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 8 TYR A  39
VAL A 230
ILE A 227
GLU A 270
 None
MES  A1353 (-3.4A)
None
None
 1.05A 4a97C-2iuyA:
undetectable		 4a97C-2iuyA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 8 TYR A  39
VAL A 230
ILE A 227
GLU A 270
 None
MES  A1353 (-3.4A)
None
None
 1.04A 4a97G-2iuyA:
undetectable		 4a97G-2iuyA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 GLY A  38
SER A 269
VAL A 273
TYR A 162
VAL A 157
 MES  A1353 ( 3.7A)
None
None
None
None
 1.36A 4ffwA-2iuyA:
3.1		 4ffwA-2iuyA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 SER A 269
VAL A 273
TYR A 162
ASN A  48
VAL A 157
 None
 1.19A 4ffwA-2iuyA:
3.1		 4ffwA-2iuyA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 GLY A  38
SER A 269
VAL A 273
TYR A 162
VAL A 157
 MES  A1353 ( 3.7A)
None
None
None
None
 1.35A 4ffwB-2iuyA:
4.6		 4ffwB-2iuyA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		6 / 12 LEU A  75
HIS A  58
VAL A  60
LEU A  18
VAL A  16
LEU A  49
 None
 1.42A 4m2wA-2iuyA:
undetectable		 4m2wA-2iuyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 8 VAL A 245
SER A 249
GLY A 280
ALA A 271
 None
 0.82A 4m48A-2iuyA:
undetectable		 4m48A-2iuyA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 GLY A  64
GLY A  81
LEU A  18
ASN A  20
LEU A  75
 None
 0.88A 4n48A-2iuyA:
undetectable		 4n48A-2iuyA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 GLY A  64
GLY A  81
LEU A  18
ASN A  20
LEU A  75
 None
 0.86A 4n48B-2iuyA:
2.9		 4n48B-2iuyA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 GLY A  64
GLY A  81
LEU A  18
ASN A  20
LEU A  75
 None
 0.88A 4n49A-2iuyA:
2.7		 4n49A-2iuyA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 4 ALA A 187
ALA A 190
ALA A 191
ALA A 194
 None
 0.11A 4oadA-2iuyA:
undetectable		 4oadA-2iuyA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 4 ALA A 187
ALA A 190
ALA A 191
ALA A 194
 None
 0.08A 4oaeA-2iuyA:
undetectable		 4oaeA-2iuyA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 8 LEU A  53
VAL A  97
TYR A 338
LEU A  18
 None
 0.99A 4puoC-2iuyA:
undetectable		 4puoC-2iuyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 8 LEU A  53
VAL A  97
TYR A 338
LEU A  18
 None
 0.96A 4pwdA-2iuyA:
undetectable		 4pwdA-2iuyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 8 LEU A  53
VAL A  97
TYR A 338
LEU A  18
 None
 1.07A 4pwdC-2iuyA:
undetectable		 4pwdC-2iuyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 8 LEU A  53
VAL A  97
TYR A 338
LEU A  18
 None
 1.00A 4q0bA-2iuyA:
undetectable		 4q0bA-2iuyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 HIS A  58
VAL A  60
VAL A  16
LEU A  49
ALA A 335
 None
 1.43A 4ygfG-2iuyA:
undetectable		 4ygfG-2iuyA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 10 HIS A  58
VAL A  60
VAL A  16
LEU A  49
ALA A 335
 None
 1.43A 4yhaB-2iuyA:
undetectable		 4yhaB-2iuyA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		6 / 12 GLY A 104
VAL A  19
ALA A  17
LEU A 345
LEU A 111
ILE A 118
 None
 1.21A 5hieA-2iuyA:
undetectable		 5hieA-2iuyA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 VAL A 267
SER A 269
LEU A 315
VAL A 293
LEU A 286
 None
 1.13A 5iktA-2iuyA:
undetectable		 5iktA-2iuyA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 9 HIS A  58
VAL A  60
VAL A  16
LEU A  49
ALA A 335
 None
 1.39A 5tt3B-2iuyA:
undetectable		 5tt3B-2iuyA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 10 GLY A  41
HIS A 122
LYS A 185
GLU A 262
PRO A 263
 None
 0.80A 5vncC-2iuyA:
19.6		 5vncC-2iuyA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 LEU A  56
GLU A 340
VAL A 339
THR A 333
ARG A 337
 None
 1.42A 5xipD-2iuyA:
2.4		 5xipD-2iuyA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		3 / 3 VAL A 152
TYR A 135
GLU A 288
 None
 0.95A 5zmqD-2iuyA:
undetectable
5zmqE-2iuyA:
undetectable		 5zmqD-2iuyA:
21.25
5zmqE-2iuyA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		5 / 12 SER A 269
VAL A 273
TYR A 162
ASN A  48
VAL A 157
 None
 1.09A 6b1eB-2iuyA:
3.8		 6b1eB-2iuyA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 2iuy GLYCOSYLTRANSFERASE
(Streptomyces
viridochromogene
s) 		4 / 6 GLU A 270
ARG A 235
VAL A  34
PRO A  35
 None
 1.49A 6fgdA-2iuyA:
4.2		 6fgdA-2iuyA:
23.13