SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ivx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 2ivx CYCLIN-T2
(Homo
sapiens) 		3 / 3 TRP A 209
VAL A 213
TRP A 220
 None
None
EDO  A1263 (-4.1A)
 1.44A 1gmkC-2ivxA:
undetectable
1gmkD-2ivxA:
undetectable		 1gmkC-2ivxA:
4.76
1gmkD-2ivxA:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 2ivx CYCLIN-T2
(Homo
sapiens) 		5 / 12 MET A 139
ILE A  44
ILE A  82
LEU A  89
VAL A  53
 None
 0.88A 3fpjB-2ivxA:
undetectable		 3fpjB-2ivxA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 2ivx CYCLIN-T2
(Homo
sapiens) 		3 / 3 ILE A 104
MET A  47
ARG A  50
 None
 0.79A 4lnwA-2ivxA:
undetectable		 4lnwA-2ivxA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 2ivx CYCLIN-T2
(Homo
sapiens) 		3 / 3 ILE A 104
MET A  47
ARG A  50
 None
 0.78A 4lnxA-2ivxA:
1.5		 4lnxA-2ivxA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 2ivx CYCLIN-T2
(Homo
sapiens) 		3 / 3 VAL A  53
SER A  54
THR A  57
 None
 0.47A 4luhA-2ivxA:
2.5		 4luhA-2ivxA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2ivx CYCLIN-T2
(Homo
sapiens) 		4 / 8 GLU A 239
LEU A 230
VAL A 194
PHE A 240
 None
 1.01A 4r38B-2ivxA:
undetectable		 4r38B-2ivxA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2ivx CYCLIN-T2
(Homo
sapiens) 		5 / 9 VAL A 198
LEU A 202
LEU A 241
GLN A 242
THR A 184
 None
 1.27A 6czmB-2ivxA:
undetectable
6czmC-2ivxA:
undetectable		 6czmB-2ivxA:
22.37
6czmC-2ivxA:
22.37