SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ivy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2ivy HYPOTHETICAL PROTEIN
SSO1404
(Sulfolobus
solfataricus) 		4 / 7 GLU A  77
ASP A  30
LEU A  29
GLY A  28
 None
 0.85A 1mt1H-2ivyA:
undetectable
1mt1K-2ivyA:
undetectable		 1mt1H-2ivyA:
20.49
1mt1K-2ivyA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2ivy HYPOTHETICAL PROTEIN
SSO1404
(Sulfolobus
solfataricus) 		4 / 7 GLU A  77
ASP A  30
LEU A  29
GLY A  28
 None
 0.85A 1n13D-2ivyA:
undetectable
1n13E-2ivyA:
undetectable		 1n13D-2ivyA:
20.49
1n13E-2ivyA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 2ivy HYPOTHETICAL PROTEIN
SSO1404
(Sulfolobus
solfataricus) 		4 / 8 ASP A  30
LEU A  29
GLY A  28
GLU A  77
 None
 0.86A 1n13A-2ivyA:
undetectable
1n13F-2ivyA:
undetectable		 1n13A-2ivyA:
22.99
1n13F-2ivyA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2ivy HYPOTHETICAL PROTEIN
SSO1404
(Sulfolobus
solfataricus) 		4 / 6 GLU A  77
ASP A  30
LEU A  29
GLY A  28
 None
 0.87A 1n13H-2ivyA:
undetectable
1n13K-2ivyA:
undetectable		 1n13H-2ivyA:
20.49
1n13K-2ivyA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 2ivy HYPOTHETICAL PROTEIN
SSO1404
(Sulfolobus
solfataricus) 		4 / 7 ASP A  30
LEU A  29
GLY A  28
GLU A  77
 None
 0.87A 1n13G-2ivyA:
undetectable
1n13J-2ivyA:
undetectable		 1n13G-2ivyA:
22.99
1n13J-2ivyA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2ivy HYPOTHETICAL PROTEIN
SSO1404
(Sulfolobus
solfataricus) 		4 / 6 ARG A  31
ALA A  21
TYR A  34
ILE A  11
 None
 1.27A 1oniB-2ivyA:
undetectable
1oniC-2ivyA:
undetectable		 1oniB-2ivyA:
21.54
1oniC-2ivyA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2ivy HYPOTHETICAL PROTEIN
SSO1404
(Sulfolobus
solfataricus) 		4 / 7 TYR A  34
ILE A  11
ARG A  31
ALA A  21
 None
 1.14A 1oniD-2ivyA:
undetectable
1oniE-2ivyA:
undetectable		 1oniD-2ivyA:
21.54
1oniE-2ivyA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1291_1
(FICOLIN-2)		 2ivy HYPOTHETICAL PROTEIN
SSO1404
(Sulfolobus
solfataricus) 		4 / 4 ASP A  30
LEU A  41
GLY A  39
ARG A  45
 None
 1.28A 2j2pD-2ivyA:
0.0
2j2pE-2ivyA:
0.0		 2j2pD-2ivyA:
19.70
2j2pE-2ivyA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 2ivy HYPOTHETICAL PROTEIN
SSO1404
(Sulfolobus
solfataricus) 		4 / 8 GLU A  77
ASP A  30
LEU A  29
GLY A  28
 None
 0.81A 2qqdB-2ivyA:
undetectable
2qqdC-2ivyA:
undetectable		 2qqdB-2ivyA:
20.69
2qqdC-2ivyA:
22.42