SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2iwg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		3 / 3 PHE B 167
LEU B  17
SER B 164
 None
 0.65A 1e7aA-2iwgB:
undetectable		 1e7aA-2iwgB:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		5 / 9 ARG B 160
THR B  12
VAL B  48
LEU B   8
ALA B  51
 None
 1.38A 1fo4A-2iwgB:
undetectable		 1fo4A-2iwgB:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		5 / 6 ARG B 160
THR B  12
VAL B  48
LEU B   8
ALA B  51
 None
 1.47A 2e1qC-2iwgB:
undetectable		 2e1qC-2iwgB:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		4 / 8 ILE B 126
GLY B  74
LEU B  49
PHE B  54
 None
 0.80A 2vctC-2iwgB:
undetectable		 2vctC-2iwgB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		5 / 8 ARG B 160
THR B  12
VAL B  48
LEU B   8
ALA B  51
 None
 1.44A 3ax7A-2iwgB:
undetectable		 3ax7A-2iwgB:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		5 / 9 ARG B 160
THR B  12
VAL B  48
LEU B   8
ALA B  51
 None
 1.45A 3ax7B-2iwgB:
undetectable		 3ax7B-2iwgB:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		4 / 6 ARG B  24
PHE B 163
PRO B 161
LEU B   8
 None
 1.28A 3tgvB-2iwgB:
undetectable		 3tgvB-2iwgB:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		4 / 6 ARG B  24
PHE B 163
PRO B 161
LEU B   8
 None
 1.26A 3tgvD-2iwgB:
undetectable		 3tgvD-2iwgB:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		5 / 9 ARG B 160
THR B  12
VAL B  48
LEU B   8
ALA B  51
 None
 1.39A 3unaA-2iwgB:
undetectable		 3unaA-2iwgB:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		5 / 9 ARG B 160
THR B  12
VAL B  48
LEU B   8
ALA B  51
 None
 1.40A 3unaB-2iwgB:
undetectable		 3unaB-2iwgB:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		5 / 9 ARG B 160
THR B  12
VAL B  48
LEU B   8
ALA B  51
 None
 1.39A 3uncA-2iwgB:
undetectable		 3uncA-2iwgB:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		5 / 9 ARG B 160
THR B  12
VAL B  48
LEU B   8
ALA B  51
 None
 1.40A 3uncB-2iwgB:
undetectable		 3uncB-2iwgB:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		5 / 7 ARG B 160
THR B  12
VAL B  48
LEU B   8
ALA B  51
 None
 1.40A 3uniA-2iwgB:
undetectable		 3uniA-2iwgB:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		3 / 3 ARG B 160
GLU B  40
THR B  12
 None
 0.80A 3v4tA-2iwgB:
undetectable		 3v4tA-2iwgB:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		3 / 3 PRO B  46
MET B  47
TYR B  45
 None
 0.91A 4qa0B-2iwgB:
undetectable		 4qa0B-2iwgB:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		3 / 3 PRO B  46
MET B  47
TYR B  45
 None
 0.91A 4qa0A-2iwgB:
undetectable		 4qa0A-2iwgB:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		3 / 3 PRO B  46
MET B  47
TYR B  45
 None
 0.82A 4qa2B-2iwgB:
undetectable		 4qa2B-2iwgB:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		5 / 9 SER B 151
PHE B 155
SER B  90
SER B  92
GLY B  93
 None
 1.47A 6awpA-2iwgB:
undetectable		 6awpA-2iwgB:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 2iwg 52 KDA RO PROTEIN
(Homo
sapiens) 		4 / 7 GLY B  57
TYR B 130
HIS B  53
GLY B 157
 None
 0.98A 6n7fA-2iwgB:
undetectable		 6n7fA-2iwgB:
17.34