SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ix4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.23A 1fk9A-2ix4A:
undetectable		 1fk9A-2ix4A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 11 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.23A 1fkpA-2ix4A:
undetectable		 1fkpA-2ix4A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 11 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.22A 1jkhA-2ix4A:
undetectable
1jkhB-2ix4A:
undetectable		 1jkhA-2ix4A:
21.23
1jkhB-2ix4A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.24A 1lw0A-2ix4A:
undetectable		 1lw0A-2ix4A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 11 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.22A 1lwcA-2ix4A:
undetectable		 1lwcA-2ix4A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 212
THR A 207
SER A 282
ALA A 399
ILE A 216
 None
 0.99A 1nt2A-2ix4A:
undetectable		 1nt2A-2ix4A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		6 / 12 ILE A 400
GLY A 283
GLY A 235
ILE A 216
VAL A  41
ALA A 122
 None
 1.40A 1sg9B-2ix4A:
undetectable		 1sg9B-2ix4A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		6 / 12 ILE A 400
GLY A 283
GLY A 235
ILE A 216
VAL A  41
ALA A 122
 None
 1.42A 1vq1B-2ix4A:
undetectable		 1vq1B-2ix4A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		6 / 12 ILE A 400
GLY A 283
GLY A 235
ILE A 216
VAL A  41
ALA A 126
 None
 1.33A 1vq1B-2ix4A:
undetectable		 1vq1B-2ix4A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VRT_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 9 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.27A 1vrtA-2ix4A:
undetectable		 1vrtA-2ix4A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 THR A 211
GLY A 234
GLY A 283
SER A 149
HIS A 203
 None
 1.13A 1wg8B-2ix4A:
undetectable		 1wg8B-2ix4A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLU A 398
HIS A 350
ALA A 454
GLY A 392
GLY A 395
 K  A1463 (-3.7A)
None
None
6NA  A1462 ( 4.3A)
None
 1.12A 1x1aA-2ix4A:
undetectable		 1x1aA-2ix4A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 11 ALA A 454
ALA A 213
LEU A 456
ALA A 399
GLU A 398
 None
None
None
None
K  A1463 (-3.7A)
 1.12A 2bxeB-2ix4A:
undetectable		 2bxeB-2ix4A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 212
GLY A 152
GLY A 151
ALA A 205
ASP A 241
 None
 1.13A 2dpmA-2ix4A:
undetectable		 2dpmA-2ix4A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HND_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.23A 2hndA-2ix4A:
undetectable		 2hndA-2ix4A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.23A 2hnyA-2ix4A:
undetectable		 2hnyA-2ix4A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		3 / 3 ASP A 274
ARG A 273
ARG A 267
 None
 0.89A 2j9dA-2ix4A:
undetectable
2j9dC-2ix4A:
undetectable		 2j9dA-2ix4A:
15.02
2j9dC-2ix4A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		6 / 12 GLY A 212
GLY A 234
ILE A 400
ALA A 205
ALA A 210
VAL A 397
 None
 1.48A 2yqzA-2ix4A:
undetectable		 2yqzA-2ix4A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		6 / 12 GLY A 212
GLY A 234
ILE A 400
ALA A 205
ALA A 210
VAL A 397
 None
 1.47A 2yqzB-2ix4A:
undetectable		 2yqzB-2ix4A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 212
GLY A 392
ALA A 205
VAL A 206
ASP A 218
 None
6NA  A1462 ( 4.3A)
None
None
None
 1.17A 2yvlD-2ix4A:
undetectable		 2yvlD-2ix4A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		4 / 6 MET A 413
ARG A  54
PRO A 268
GLY A 388
 None
 1.47A 3aqiA-2ix4A:
2.1		 3aqiA-2ix4A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 6 GLY A 152
GLY A 235
GLY A 212
GLY A 392
GLY A 395
 None
None
None
6NA  A1462 ( 4.3A)
None
 0.87A 3bogB-2ix4A:
0.0
3bogD-2ix4A:
0.0		 3bogB-2ix4A:
undetectable
3bogD-2ix4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 155
GLY A 153
GLU A 237
ASN A 117
ALA A 116
 None
6NA  A1462 (-3.6A)
6NA  A1462 (-3.9A)
None
None
 1.16A 3ckkA-2ix4A:
undetectable		 3ckkA-2ix4A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 212
GLY A 395
ALA A 399
ALA A 454
ALA A 233
 None
 1.01A 3jb2A-2ix4A:
undetectable		 3jb2A-2ix4A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 ILE A 216
GLY A 234
GLY A 235
ALA A 126
ALA A 204
 None
 0.99A 3jb2A-2ix4A:
undetectable		 3jb2A-2ix4A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		4 / 6 SER A 460
LEU A 287
ILE A 300
LEU A 457
 None
 0.85A 3kk6A-2ix4A:
undetectable		 3kk6A-2ix4A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP0_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 9 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.27A 3lp0A-2ix4A:
0.0		 3lp0A-2ix4A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.28A 3lp1A-2ix4A:
undetectable		 3lp1A-2ix4A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 9 GLY A 306
GLN A 224
ARG A 221
GLU A 303
LEU A 456
 None
 1.43A 3nbqA-2ix4A:
undetectable		 3nbqA-2ix4A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		4 / 8 LEU A 390
ALA A 351
GLY A  61
PRO A  43
 None
 0.87A 3ny4A-2ix4A:
undetectable		 3ny4A-2ix4A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.24A 3qipA-2ix4A:
undetectable		 3qipA-2ix4A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 212
GLY A 392
SER A 149
GLU A 398
ALA A 213
 None
6NA  A1462 ( 4.3A)
None
K  A1463 (-3.7A)
None
 1.23A 3t7sA-2ix4A:
undetectable		 3t7sA-2ix4A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 212
GLY A 392
SER A 149
GLU A 398
ALA A 213
 None
6NA  A1462 ( 4.3A)
None
K  A1463 (-3.7A)
None
 1.20A 3t7sB-2ix4A:
undetectable		 3t7sB-2ix4A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 212
GLY A 392
SER A 149
GLU A 398
ALA A 213
 None
6NA  A1462 ( 4.3A)
None
K  A1463 (-3.7A)
None
 1.21A 3t7sC-2ix4A:
undetectable		 3t7sC-2ix4A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 212
GLY A 392
SER A 149
GLU A 398
ALA A 213
 None
6NA  A1462 ( 4.3A)
None
K  A1463 (-3.7A)
None
 1.20A 3t7sD-2ix4A:
undetectable		 3t7sD-2ix4A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 8 GLY A 212
GLY A 395
GLY A 217
ILE A 285
LEU A 304
 None
 1.26A 3v1nA-2ix4A:
undetectable		 3v1nA-2ix4A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLY A  61
ASN A 348
SER A 381
MET A 413
LEU A 415
 None
K  A1463 (-3.9A)
None
None
None
 1.49A 4a83A-2ix4A:
undetectable		 4a83A-2ix4A:
17.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		7 / 12 ALA A 208
CYH A 209
SER A 239
HIS A 350
THR A 352
HIS A 389
GLY A 448
 6NA  A1462 (-3.4A)
6NA  A1462 (-1.7A)
None
None
None
None
6NA  A1462 (-3.2A)
 1.06A 4ls7A-2ix4A:
63.5		 4ls7A-2ix4A:
47.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		11 / 12 GLY A 153
ALA A 208
CYH A 209
GLU A 237
PHE A 248
HIS A 350
THR A 352
HIS A 389
LEU A 391
GLY A 448
PHE A 449
 6NA  A1462 (-3.6A)
6NA  A1462 (-3.4A)
6NA  A1462 (-1.7A)
6NA  A1462 (-3.9A)
6NA  A1462 (-4.7A)
None
None
None
6NA  A1462 ( 3.9A)
6NA  A1462 (-3.2A)
6NA  A1462 (-3.6A)
 0.28A 4ls7A-2ix4A:
63.5		 4ls7A-2ix4A:
47.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		8 / 12 GLY A 153
ALA A 208
GLU A 237
SER A 244
PHE A 248
LEU A 391
GLY A 448
PHE A 449
 6NA  A1462 (-3.6A)
6NA  A1462 (-3.4A)
6NA  A1462 (-3.9A)
None
6NA  A1462 (-4.7A)
6NA  A1462 ( 3.9A)
6NA  A1462 (-3.2A)
6NA  A1462 (-3.6A)
 0.65A 4ls7A-2ix4A:
63.5		 4ls7A-2ix4A:
47.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		8 / 12 GLY A 392
ALA A 208
CYH A 209
GLU A 237
PHE A 248
LEU A 391
GLY A 448
PHE A 449
 6NA  A1462 ( 4.3A)
6NA  A1462 (-3.4A)
6NA  A1462 (-1.7A)
6NA  A1462 (-3.9A)
6NA  A1462 (-4.7A)
6NA  A1462 ( 3.9A)
6NA  A1462 (-3.2A)
6NA  A1462 (-3.6A)
 1.47A 4ls7A-2ix4A:
63.5		 4ls7A-2ix4A:
47.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		9 / 12 ALA A 208
CYH A 209
PHE A 248
HIS A 350
THR A 352
HIS A 389
LEU A 391
GLY A 448
PHE A 449
 6NA  A1462 (-3.4A)
6NA  A1462 (-1.7A)
6NA  A1462 (-4.7A)
None
None
None
6NA  A1462 ( 3.9A)
6NA  A1462 (-3.2A)
6NA  A1462 (-3.6A)
 0.30A 4ls7A-2ix4A:
63.5
4ls7B-2ix4A:
63.4		 4ls7A-2ix4A:
47.77
4ls7B-2ix4A:
47.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		8 / 12 ALA A 208
CYH A 209
SER A 239
HIS A 350
THR A 352
HIS A 389
GLY A 448
PHE A 449
 6NA  A1462 (-3.4A)
6NA  A1462 (-1.7A)
None
None
None
None
6NA  A1462 (-3.2A)
6NA  A1462 (-3.6A)
 1.12A 4ls7A-2ix4A:
63.5
4ls7B-2ix4A:
63.4		 4ls7A-2ix4A:
47.77
4ls7B-2ix4A:
47.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		7 / 12 ALA A 208
CYH A 209
SER A 244
PHE A 248
LEU A 391
GLY A 448
PHE A 449
 6NA  A1462 (-3.4A)
6NA  A1462 (-1.7A)
None
6NA  A1462 (-4.7A)
6NA  A1462 ( 3.9A)
6NA  A1462 (-3.2A)
6NA  A1462 (-3.6A)
 0.66A 4ls7A-2ix4A:
63.5
4ls7B-2ix4A:
63.4		 4ls7A-2ix4A:
47.77
4ls7B-2ix4A:
47.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		6 / 12 ILE A 154
ALA A 208
CYH A 209
HIS A 350
HIS A 389
GLY A 448
 6NA  A1462 ( 4.9A)
6NA  A1462 (-3.4A)
6NA  A1462 (-1.7A)
None
None
6NA  A1462 (-3.2A)
 0.57A 4ls7A-2ix4A:
63.5
4ls7B-2ix4A:
63.4		 4ls7A-2ix4A:
47.77
4ls7B-2ix4A:
47.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 10 VAL A 232
ALA A 233
GLY A 197
PHE A 198
SER A 189
 None
 1.26A 4mmdA-2ix4A:
undetectable		 4mmdA-2ix4A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		4 / 6 LEU A 378
MET A 437
LEU A 431
VAL A 417
 None
 1.20A 4okbA-2ix4A:
undetectable		 4okbA-2ix4A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 8 ALA A 396
ALA A 213
ILE A 216
ALA A 442
LEU A 304
 None
 1.31A 4v1fA-2ix4A:
undetectable
4v1fB-2ix4A:
undetectable		 4v1fA-2ix4A:
13.88
4v1fB-2ix4A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		3 / 3 MET A 222
HIS A 203
GLY A 217
 None
 0.73A 5gwzB-2ix4A:
undetectable		 5gwzB-2ix4A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 11 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.25A 5hbmA-2ix4A:
undetectable		 5hbmA-2ix4A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		3 / 3 ASP A 345
ASN A 342
PHE A 458
 None
 0.88A 5jglB-2ix4A:
undetectable		 5jglB-2ix4A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 7 GLY A 152
GLY A 155
LEU A 390
THR A 236
ALA A 393
 None
 1.13A 5o96C-2ix4A:
undetectable		 5o96C-2ix4A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 7 LEU A 287
LEU A 457
ILE A 285
GLY A  37
LEU A  38
 None
 1.38A 5vkqA-2ix4A:
undetectable
5vkqB-2ix4A:
undetectable		 5vkqA-2ix4A:
12.80
5vkqB-2ix4A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 392
GLY A 234
GLY A 212
VAL A 206
ILE A 400
 6NA  A1462 ( 4.3A)
None
None
None
None
 1.18A 5x7fA-2ix4A:
undetectable		 5x7fA-2ix4A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.26A 6bsgA-2ix4A:
undetectable		 6bsgA-2ix4A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A 148
VAL A 230
GLY A 147
TYR A 196
 None
 1.27A 6bsjA-2ix4A:
undetectable		 6bsjA-2ix4A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		4 / 8 GLY A  61
THR A  51
VAL A 397
LEU A 390
 None
 0.84A 6czmD-2ix4A:
undetectable
6czmF-2ix4A:
undetectable		 6czmD-2ix4A:
24.31
6czmF-2ix4A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		4 / 4 HIS A 292
LEU A 130
TYR A 196
GLY A 147
 None
 1.40A 6n91A-2ix4A:
undetectable		 6n91A-2ix4A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 2ix4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Arabidopsis
thaliana) 		4 / 4 HIS A 292
LEU A 130
TYR A 196
GLY A 147
 None
 1.40A 6n91B-2ix4A:
undetectable		 6n91B-2ix4A:
10.24