SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ixb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		4 / 4 ILE A 295
MET A 236
VAL A 151
GLY A 175
 None
None
A2G  A1446 (-4.9A)
None
 1.35A 1e06B-2ixbA:
undetectable		 1e06B-2ixbA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		4 / 6 ILE A 414
LYS A 278
ALA A 255
VAL A 283
 None
 1.01A 1hk1A-2ixbA:
undetectable		 1hk1A-2ixbA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		5 / 11 VAL A  48
ALA A  49
PHE A  25
ILE A  92
ARG A  31
 None
None
None
None
NAD  A1445 (-3.4A)
 1.12A 3n23A-2ixbA:
2.5		 3n23A-2ixbA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		4 / 8 HIS A 104
SER A  98
ASP A 380
LEU A 379
 NAD  A1445 (-4.0A)
None
None
None
 1.09A 3n2oC-2ixbA:
undetectable
3n2oD-2ixbA:
undetectable		 3n2oC-2ixbA:
21.25
3n2oD-2ixbA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		5 / 12 TYR A 217
GLY A 257
LEU A 303
ALA A 252
HIS A 299
 None
 1.32A 3ou7C-2ixbA:
3.0		 3ou7C-2ixbA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		3 / 3 HIS A 299
SER A 250
ASN A 221
 None
 0.86A 3s8pB-2ixbA:
undetectable		 3s8pB-2ixbA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		3 / 3 PHE A 323
SER A 348
SER A 347
 None
 1.01A 3ufgB-2ixbA:
undetectable		 3ufgB-2ixbA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		3 / 3 ASP A 198
GLU A 201
GLY A 191
 None
 0.70A 3w9tA-2ixbA:
undetectable		 3w9tA-2ixbA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		5 / 12 ASP A  44
TYR A 444
TYR A 377
VAL A  21
ILE A  23
 None
MRD  A1447 (-4.6A)
None
None
None
 1.42A 4eb6B-2ixbA:
undetectable
4eb6C-2ixbA:
3.6		 4eb6B-2ixbA:
20.66
4eb6C-2ixbA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		4 / 5 ALA A  27
ASP A  52
MET A  57
ASN A  80
 NAD  A1445 (-3.4A)
NAD  A1445 (-2.7A)
NAD  A1445 (-4.3A)
NAD  A1445 (-4.4A)
 0.99A 4obwC-2ixbA:
3.6		 4obwC-2ixbA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		4 / 6 GLU A 223
THR A 284
THR A 294
HIS A 174
 None
 1.27A 4pfjB-2ixbA:
4.3		 4pfjB-2ixbA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		3 / 3 ARG A 244
ASP A 425
TRP A 431
 None
 1.04A 4xdqA-2ixbA:
undetectable		 4xdqA-2ixbA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		5 / 12 PHE A  96
THR A  34
ARG A  31
HIS A 372
GLY A 374
 None
None
NAD  A1445 (-3.4A)
None
None
 1.42A 4ydqB-2ixbA:
undetectable		 4ydqB-2ixbA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		4 / 6 TYR A 217
HIS A 299
GLY A 222
GLU A 223
 None
 1.37A 4zbqA-2ixbA:
undetectable		 4zbqA-2ixbA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		5 / 8 VAL A  36
ILE A  47
ALA A  49
VAL A  58
VAL A  28
 None
 1.44A 5l94A-2ixbA:
undetectable		 5l94A-2ixbA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		4 / 8 GLU A 223
GLY A 229
GLN A 180
LEU A 309
 None
 1.04A 5sxqB-2ixbA:
undetectable		 5sxqB-2ixbA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		4 / 8 GLU A 223
GLY A 229
GLN A 180
LEU A 309
 None
 1.10A 5syjA-2ixbA:
undetectable		 5syjA-2ixbA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2ixb ALPHA-N-ACETYLGALACT
OSAMINIDASE
(Elizabethkingia
meningoseptica) 		5 / 11 GLY A 229
GLN A 180
THR A 284
THR A 285
GLY A 175
 None
 1.29A 5w97A-2ixbA:
0.0
5w97B-2ixbA:
0.0
5w97g-2ixbA:
0.0		 5w97A-2ixbA:
21.90
5w97B-2ixbA:
18.14
5w97g-2ixbA:
12.26