SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2iz7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2iz7 MOCO CARRIER PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 10 ILE A 157
ILE A  33
LYS A  58
GLY A  56
VAL A 106
 None
 1.29A 3em0A-2iz7A:
undetectable		 3em0A-2iz7A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2iz7 MOCO CARRIER PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 8 LEU A 128
VAL A 160
LEU A 163
GLY A 145
 None
 0.87A 4r3aA-2iz7A:
undetectable		 4r3aA-2iz7A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2iz7 MOCO CARRIER PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 12 THR A  64
GLY A  44
GLY A  66
LEU A  47
THR A  18
 None
 1.15A 4uckB-2iz7A:
undetectable		 4uckB-2iz7A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 2iz7 MOCO CARRIER PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 12 VAL A 153
GLY A 155
ALA A 159
GLU A  52
VAL A  10
 None
 1.16A 6bqgA-2iz7A:
undetectable		 6bqgA-2iz7A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 2iz7 MOCO CARRIER PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 10 LEU A 120
VAL A 126
ALA A 105
THR A 131
ALA A 135
 None
 1.40A 6h1lA-2iz7A:
undetectable		 6h1lA-2iz7A:
16.96