SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j04'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		4 / 5 PHE B 458
VAL B 482
VAL B 462
ASP B 460
 None
 1.23A 1dz6B-2j04B:
undetectable		 1dz6B-2j04B:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_B_CAMB502_0
(CYTOCHROME P450-CAM)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 9 PHE B 458
VAL B 482
THR B 484
VAL B 462
ASP B 460
 None
 1.48A 1dz9B-2j04B:
undetectable		 1dz9B-2j04B:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 462
LEU A 458
LEU A 475
LEU A 427
LEU A 430
 None
 0.87A 1errB-2j04A:
undetectable		 1errB-2j04A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 10 PHE B 458
VAL B 482
THR B 484
VAL B 462
ASP B 460
 None
 1.48A 1o76A-2j04B:
undetectable		 1o76A-2j04B:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 324
ASN A 326
TRP A 321
SER A 318
 None
 1.05A 1rqpB-2j04A:
undetectable		 1rqpB-2j04A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 324
ASN A 326
TRP A 321
SER A 318
 None
 1.06A 1rqpC-2j04A:
undetectable		 1rqpC-2j04A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 324
ASN A 326
TRP A 321
SER A 318
 None
 1.08A 1rqpA-2j04A:
undetectable		 1rqpA-2j04A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		6 / 12 LEU B 276
ARG B 281
PHE B 273
LEU B 256
ILE B 285
ILE B 616
 None
 1.48A 2bxqA-2j04B:
undetectable		 2bxqA-2j04B:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  39
SER A  38
ILE A  37
VAL A 102
ILE A 368
 None
 0.92A 2nnhA-2j04A:
undetectable		 2nnhA-2j04A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		4 / 7 ASN B 287
GLY B 289
THR B 293
SER B 660
 None
 1.15A 2o5yH-2j04B:
undetectable
2o5yL-2j04B:
undetectable		 2o5yH-2j04B:
19.66
2o5yL-2j04B:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 12 ALA B 296
PHE B 386
SER B 385
ILE B 359
LEU B 396
 None
 1.04A 2oipA-2j04B:
undetectable		 2oipA-2j04B:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 12 ALA B 296
PHE B 386
SER B 385
ILE B 359
LEU B 396
 None
 0.99A 2oipD-2j04B:
undetectable		 2oipD-2j04B:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 369
PHE B 386
SER B 385
ILE B 359
LEU B 396
 None
 1.16A 2oipD-2j04B:
undetectable		 2oipD-2j04B:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_E_MTXE621_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 12 ALA B 296
PHE B 386
SER B 385
ILE B 359
LEU B 396
 None
 1.02A 2oipE-2j04B:
undetectable		 2oipE-2j04B:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_E_MTXE621_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 369
PHE B 386
SER B 385
ILE B 359
LEU B 396
 None
 1.10A 2oipE-2j04B:
undetectable		 2oipE-2j04B:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 324
ASN A 326
TRP A 321
SER A 318
 None
 1.06A 2v7uA-2j04A:
undetectable		 2v7uA-2j04A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 324
ASN A 326
TRP A 321
SER A 318
 None
 1.07A 2v7uB-2j04A:
undetectable		 2v7uB-2j04A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		4 / 7 SER A 142
VAL A 111
ILE A 158
ASP A  97
 None
 0.95A 2x45B-2j04A:
undetectable		 2x45B-2j04A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		4 / 7 SER A 142
VAL A 111
ILE A 158
ASP A  97
 None
 0.94A 2x45C-2j04A:
undetectable		 2x45C-2j04A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 534
LEU A 485
LYS A 486
ARG A 529
 None
 0.95A 2xn3A-2j04A:
undetectable
2xn3B-2j04A:
undetectable		 2xn3A-2j04A:
20.26
2xn3B-2j04A:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		3 / 3 ASP B 460
THR B 451
GLU B 447
 None
 0.77A 2zifB-2j04B:
undetectable		 2zifB-2j04B:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 12 GLY B 289
GLY B 664
ASP B 294
LEU B 665
ASP B 269
 None
 1.18A 2zw9B-2j04B:
6.0		 2zw9B-2j04B:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 552
PHE A 454
LEU A 455
SER A 548
SER A 578
 None
 1.47A 3apvA-2j04A:
undetectable		 3apvA-2j04A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		4 / 7 SER A 142
VAL A 111
ILE A 158
ASP A  97
 None
 0.88A 3bu1A-2j04A:
undetectable		 3bu1A-2j04A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		3 / 3 TYR A 169
GLU A 141
ASP A 193
 None
 0.80A 3bxoA-2j04A:
undetectable		 3bxoA-2j04A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		3 / 3 TYR A 169
GLU A 141
ASP A 193
 None
 0.89A 3bxoB-2j04A:
undetectable		 3bxoB-2j04A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 298
ALA B 658
ALA B 558
GLY B 575
ILE B 285
 None
 0.97A 3c6gA-2j04B:
undetectable		 3c6gA-2j04B:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		4 / 6 ILE B 425
THR B 484
PHE B 494
PHE B 458
 None
 1.16A 3elzB-2j04B:
undetectable		 3elzB-2j04B:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 451
PHE A 454
ILE A 484
VAL A 552
LEU A 570
 None
 1.34A 3eqmA-2j04A:
0.0		 3eqmA-2j04A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_B_TMQB612_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 9 VAL B 381
ILE B 227
THR B 233
SER B 415
ILE B 398
 None
 1.33A 3hbbB-2j04B:
undetectable		 3hbbB-2j04B:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 12 ALA B 296
PHE B 386
SER B 385
ILE B 359
LEU B 396
 None
 1.09A 3hj3A-2j04B:
undetectable		 3hj3A-2j04B:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 12 ALA B 296
PHE B 386
SER B 385
ILE B 359
LEU B 396
 None
 1.07A 3hj3B-2j04B:
undetectable		 3hj3B-2j04B:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		3 / 3 ASP B 574
SER B 576
ARG B 601
 None
 0.99A 3loqA-2j04B:
undetectable		 3loqA-2j04B:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		4 / 6 TYR B 312
ASN B 401
LEU B 380
ASP B 400
 None
 1.00A 3lslG-2j04B:
undetectable		 3lslG-2j04B:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		4 / 6 VAL B 462
PHE B 494
VAL B 470
PHE B 458
 None
 1.08A 3soaA-2j04B:
undetectable		 3soaA-2j04B:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 458
LEU A 427
ILE A 555
ILE A 553
PHE A 566
 None
 1.19A 3tmzA-2j04A:
undetectable		 3tmzA-2j04A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  97
LEU A 118
VAL A 109
 None
 0.71A 4jecB-2j04A:
undetectable		 4jecB-2j04A:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		3 / 3 VAL B 288
GLY B 268
LYS B 270
 None
 0.77A 4k50A-2j04B:
undetectable		 4k50A-2j04B:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		3 / 3 SER B 457
ALA B 446
VAL B 445
 None
 0.58A 4o2bA-2j04B:
undetectable		 4o2bA-2j04B:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		3 / 3 SER B 457
ALA B 446
VAL B 445
 None
 0.55A 4o2bC-2j04B:
undetectable		 4o2bC-2j04B:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		4 / 5 ASN A  77
LEU A  80
GLU A 149
THR A 131
 None
 1.21A 4p6sA-2j04A:
0.0		 4p6sA-2j04A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		3 / 3 SER B 457
ALA B 446
VAL B 445
 None
 0.55A 4x1iA-2j04B:
undetectable		 4x1iA-2j04B:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 294
ASP A 296
ILE A 234
 None
 0.64A 4xi3D-2j04A:
undetectable		 4xi3D-2j04A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		4 / 8 ASN B 495
PRO B 496
SER B 483
TYR B 526
 None
 1.14A 5amiB-2j04B:
undetectable		 5amiB-2j04B:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		3 / 3 TYR A  30
THR A  32
THR A  22
 None
 0.81A 5aoxB-2j04A:
undetectable		 5aoxB-2j04A:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		3 / 3 TYR A  30
THR A  32
THR A  22
 None
 0.81A 5aoxE-2j04A:
undetectable		 5aoxE-2j04A:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		3 / 3 SER B 457
ALA B 446
VAL B 445
 None
 0.54A 5eypA-2j04B:
undetectable		 5eypA-2j04B:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		3 / 3 PRO A 216
ILE A 158
SER A 218
 None
 0.81A 5fsaA-2j04A:
undetectable		 5fsaA-2j04A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
YDR362CP
(Saccharomyces
cerevisiae) 		3 / 3 PRO A 244
ILE A 234
SER B 457
 None
 0.77A 5fsaA-2j04A:
undetectable		 5fsaA-2j04A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 9 SER B 562
GLY B 560
ALA B 582
VAL B 568
ILE B 559
 None
 1.43A 5i3cA-2j04B:
undetectable		 5i3cA-2j04B:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		3 / 3 GLY B 653
GLY B 654
GLN B 204
 None
 0.49A 5imsA-2j04B:
undetectable		 5imsA-2j04B:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		4 / 8 SER B 572
THR B 554
ARG B 601
ILE B 578
 None
 1.07A 5jhdE-2j04B:
undetectable
5jhdG-2j04B:
undetectable		 5jhdE-2j04B:
16.76
5jhdG-2j04B:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		5 / 12 TRP A  23
ILE A 394
ALA A 371
LEU A  31
LEU A  29
 None
 1.20A 5jkvA-2j04A:
undetectable		 5jkvA-2j04A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 451
PHE A 454
ILE A 484
VAL A 552
LEU A 570
 None
 1.31A 5jkwA-2j04A:
undetectable		 5jkwA-2j04A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		4 / 6 VAL B 226
LEU B 384
SER B 385
ILE B 341
 None
 1.06A 5jw1A-2j04B:
undetectable		 5jw1A-2j04B:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  70
ASN A 105
GLN A  83
 None
 0.78A 5k7uA-2j04A:
undetectable		 5k7uA-2j04A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 2j04 HYPOTHETICAL PROTEIN
YPL007C
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 342
TYR A 343
TYR A 395
PHE A  56
LEU A  29
 None
 1.48A 5kklB-2j04A:
undetectable		 5kklB-2j04A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		4 / 6 TYR B 607
LEU B 665
GLY B 664
TYR B 286
 None
 0.98A 5nooC-2j04B:
undetectable		 5nooC-2j04B:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 8 ARG B 615
TYR B 607
LEU B 665
GLY B 664
TYR B 286
 None
 1.44A 5nooD-2j04B:
undetectable		 5nooD-2j04B:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 12 VAL B 482
SER B 483
THR B 484
LEU B 431
VAL B 436
 None
 1.15A 6a94B-2j04B:
undetectable		 6a94B-2j04B:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		5 / 12 VAL B 445
ASP B 460
LEU B 450
THR B 434
PRO B 496
 None
 1.09A 6b0lB-2j04B:
undetectable		 6b0lB-2j04B:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 2j04 YDR362CP
(Saccharomyces
cerevisiae) 		4 / 5 THR B 557
CYH B 644
THR B 645
GLY B 571
 None
 1.10A 6gtqA-2j04B:
undetectable		 6gtqA-2j04B:
14.51