SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1359_1 (PROSTAGLANDIN REDUCTASE 2)	2j0n	INVASIN IPAD (Shigella flexneri)	4 / 6	THR A 289 GLU A 288 MET A 256 PHE A 283	None	1.33A	2w98B-2j0nA: undetectable	2w98B-2j0nA: 19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RV5_A_DXCA91_0 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	2j0n	INVASIN IPAD (Shigella flexneri)	3 / 3	PHE A 167 GLN A 295 PHE A 283	None	0.72A	3rv5A-2j0nA: 1.7	3rv5A-2j0nA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_A_CHDA504_0 (FERROCHELATASE, MITOCHONDRIAL)	2j0n	INVASIN IPAD (Shigella flexneri)	5 / 12	LEU A 257 LEU A 260 LEU A 190 ILE A 253 VAL A 170	None	1.25A	4f4dA-2j0nA: undetectable	4f4dA-2j0nA: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JQB_B_IBPB706_1 (ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1 ENVELOPE GLYCOPROTEIN 2)	2j0n	INVASIN IPAD (Shigella flexneri)	5 / 8	ALA A 198 LEU A 174 LEU A 171 LEU A 260 MET A 256	None	1.40A	5jqbA-2j0nA: undetectable 5jqbB-2j0nA: undetectable	5jqbA-2j0nA: 20.17 5jqbB-2j0nA: 22.27

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2W98_B_P1ZB1359_1","PROSTAGLANDIN REDUCTASE 2","2j0n","INVASIN IPAD","Shigella flexneri",4,"THR A 289;GLU A 288;MET A 256;PHE A 283","None","1.33A","2w98B-2j0nA:undetectable","2w98B-2j0nA:19.66"],["3RV5_A_DXCA91_0","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","2j0n","INVASIN IPAD","Shigella flexneri",3,"PHE A 167;GLN A 295;PHE A 283","None","0.72A","3rv5A-2j0nA:1.7","3rv5A-2j0nA:16.67"],["4F4D_A_CHDA504_0","FERROCHELATASE, MITOCHONDRIAL","2j0n","INVASIN IPAD","Shigella flexneri",5,"LEU A 257;LEU A 260;LEU A 190;ILE A 253;VAL A 170","None","1.25A","4f4dA-2j0nA:undetectable","4f4dA-2j0nA:19.67"],["5JQB_B_IBPB706_1","ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1;ENVELOPE GLYCOPROTEIN 2","2j0n","INVASIN IPAD","Shigella flexneri",5,"ALA A 198;LEU A 174;LEU A 171;LEU A 260;MET A 256","None","1.40A","5jqbA-2j0nA:undetectable;5jqbB-2j0nA:undetectable","5jqbA-2j0nA:20.17;5jqbB-2j0nA:22.27"]]