SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j0v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 2j0v RAC-LIKE GTP-BINDING
PROTEIN ARAC7
(Arabidopsis
thaliana) 		3 / 3 ALA A  91
VAL A  96
TRP A 100
 None
 1.01A 1c4dA-2j0vA:
undetectable
1c4dB-2j0vA:
undetectable		 1c4dA-2j0vA:
12.22
1c4dB-2j0vA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 2j0v RAC-LIKE GTP-BINDING
PROTEIN ARAC7
(Arabidopsis
thaliana) 		5 / 10 GLY A  77
ALA A  78
ASP A  79
GLY A  57
THR A  61
 None
 1.00A 1t7iA-2j0vA:
undetectable		 1t7iA-2j0vA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2j0v RAC-LIKE GTP-BINDING
PROTEIN ARAC7
(Arabidopsis
thaliana) 		5 / 12 GLU A 155
ILE A 148
LEU A  97
GLY A 141
SER A 138
 None
 1.24A 2e7fA-2j0vA:
3.1		 2e7fA-2j0vA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2j0v RAC-LIKE GTP-BINDING
PROTEIN ARAC7
(Arabidopsis
thaliana) 		5 / 12 GLU A 155
ILE A 148
LEU A  97
GLY A 141
SER A 138
 None
 1.25A 2ogyA-2j0vA:
undetectable		 2ogyA-2j0vA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 2j0v RAC-LIKE GTP-BINDING
PROTEIN ARAC7
(Arabidopsis
thaliana) 		5 / 10 GLY A  77
ALA A  78
ASP A  79
GLY A  57
THR A  61
 None
 1.04A 3el9B-2j0vA:
undetectable		 3el9B-2j0vA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 2j0v RAC-LIKE GTP-BINDING
PROTEIN ARAC7
(Arabidopsis
thaliana) 		4 / 8 GLU A 155
GLN A 162
ARG A 123
ASP A 124
 None
 1.19A 3mjrD-2j0vA:
4.8		 3mjrD-2j0vA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 2j0v RAC-LIKE GTP-BINDING
PROTEIN ARAC7
(Arabidopsis
thaliana) 		5 / 9 GLY A  77
ALA A  78
ASP A  79
ILE A  80
GLY A  57
 None
 0.67A 3ogpA-2j0vA:
undetectable		 3ogpA-2j0vA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC2_1
(CYTOCHROME P450 2D6)		 2j0v RAC-LIKE GTP-BINDING
PROTEIN ARAC7
(Arabidopsis
thaliana) 		5 / 10 THR A  27
VAL A 167
LEU A  58
VAL A  10
THR A  11
 None
 1.41A 3tbgC-2j0vA:
undetectable		 3tbgC-2j0vA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2j0v RAC-LIKE GTP-BINDING
PROTEIN ARAC7
(Arabidopsis
thaliana) 		5 / 12 GLU A 155
ILE A 148
LEU A  97
GLY A 141
SER A 138
 None
 1.31A 4djfB-2j0vA:
undetectable		 4djfB-2j0vA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 2j0v RAC-LIKE GTP-BINDING
PROTEIN ARAC7
(Arabidopsis
thaliana) 		3 / 3 TYR A  75
GLN A  64
TRP A  59
 None
 1.14A 4kn2C-2j0vA:
undetectable		 4kn2C-2j0vA:
19.65