SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 5 SER A 106
SER A 104
VAL A 113
PHE A 110
 None
 1.41A 1oipA-2j13A:
undetectable		 1oipA-2j13A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		5 / 12 GLU A 121
PHE A 110
LEU A  90
GLY A  80
SER A 106
 None
 1.24A 2e7fA-2j13A:
3.2		 2e7fA-2j13A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		5 / 12 GLU A 121
PHE A 110
LEU A  90
GLY A  80
SER A 106
 None
 1.22A 2e7fB-2j13A:
3.1		 2e7fB-2j13A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 5 ASP A  65
LEU A  64
MET A  93
ARG A  92
 None
 1.29A 2gj5A-2j13A:
undetectable		 2gj5A-2j13A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 6 PRO A 143
LEU A 122
ARG A 142
GLY A 101
 None
 1.18A 2hs2B-2j13A:
undetectable		 2hs2B-2j13A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		5 / 12 GLU A 121
PHE A 110
LEU A  90
GLY A  80
SER A 106
 None
 1.26A 2ogyA-2j13A:
3.0		 2ogyA-2j13A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		5 / 12 GLU A 121
PHE A 110
LEU A  90
GLY A  80
SER A 106
 None
 1.19A 2ogyB-2j13A:
3.1		 2ogyB-2j13A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 5 VAL A 164
TYR A 162
VAL A 232
ASP A 229
 None
 1.19A 2x45A-2j13A:
undetectable		 2x45A-2j13A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		5 / 12 GLN A 135
THR A 133
ASN A 102
GLY A 101
LEU A 122
 None
 1.41A 3aobC-2j13A:
undetectable		 3aobC-2j13A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		5 / 12 GLN A 135
THR A 133
ASN A 102
GLY A 101
LEU A 122
 None
 1.35A 3aodC-2j13A:
undetectable		 3aodC-2j13A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		5 / 12 GLU A 121
PHE A 110
LEU A  90
GLY A  80
SER A 106
 None
 1.38A 4djfB-2j13A:
3.1		 4djfB-2j13A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUZ_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		3 / 3 LYS A  45
PRO A 194
LYS A 221
 None
 1.50A 4duzL-2j13A:
undetectable		 4duzL-2j13A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 8 ASP A  52
HIS A 103
HIS A 107
PRO A 144
 CAC  A1242 ( 3.3A)
ZN  A1236 (-3.2A)
ZN  A1236 (-3.2A)
None
 0.35A 5nekB-2j13A:
18.6		 5nekB-2j13A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 8 ASP A  52
HIS A 103
HIS A 107
TRP A 166
 CAC  A1242 ( 3.3A)
ZN  A1236 (-3.2A)
ZN  A1236 (-3.2A)
ACT  A1241 (-4.4A)
 0.31A 5nekD-2j13A:
18.5		 5nekD-2j13A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 6 ASP A  52
HIS A 103
HIS A 107
LEU A 199
 CAC  A1242 ( 3.3A)
ZN  A1236 (-3.2A)
ZN  A1236 (-3.2A)
ACT  A1241 (-4.7A)
 0.62A 5nelB-2j13A:
18.6
5nelC-2j13A:
18.7		 5nelB-2j13A:
29.48
5nelC-2j13A:
29.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		4 / 5 ALA A  74
VAL A  72
PHE A  51
ILE A 215
 None
 1.04A 5of1B-2j13A:
undetectable		 5of1B-2j13A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2j13 POLYSACCHARIDE
DEACETYLASE
(Bacillus
anthracis) 		3 / 3 MET A 159
GLU A 116
ARG A 119
 None
 1.08A 5tjzA-2j13A:
undetectable		 5tjzA-2j13A:
22.50