SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j16'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 2j16 TYROSINE-PROTEIN
PHOSPHATASE YIL113W
(Saccharomyces
cerevisiae) 		4 / 8 ILE B  55
ASN B 178
GLY B 143
LEU B  70
 None
None
SO4  B1198 (-3.8A)
None
 0.90A 1dzmA-2j16B:
undetectable		 1dzmA-2j16B:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 2j16 TYROSINE-PROTEIN
PHOSPHATASE YIL113W
(Saccharomyces
cerevisiae) 		4 / 4 HIS B 139
VAL B  85
THR B  75
LEU B  80
 None
 1.30A 1oq5A-2j16B:
undetectable		 1oq5A-2j16B:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 2j16 TYROSINE-PROTEIN
PHOSPHATASE YIL113W
(Saccharomyces
cerevisiae) 		4 / 6 GLN B 114
TRP B 109
ALA B 116
GLN B 186
 None
 1.22A 6f6jC-2j16B:
undetectable
6f6jD-2j16B:
undetectable		 6f6jC-2j16B:
21.56
6f6jD-2j16B:
21.56