SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 2j1d DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1
(Homo
sapiens) 		3 / 3 ASP G 845
THR G 855
GLU G 989
 None
 0.75A 1pj7A-2j1dG:
undetectable		 1pj7A-2j1dG:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 2j1d DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1
(Homo
sapiens) 		5 / 10 ILE G 975
LEU G 813
ILE G 837
SER G 807
PHE G 976
 None
 1.01A 2w9sD-2j1dG:
undetectable		 2w9sD-2j1dG:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 2j1d DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1
(Homo
sapiens) 		5 / 10 ILE G 975
LEU G 813
ILE G 837
SER G 807
PHE G 976
 None
 1.02A 2w9sF-2j1dG:
undetectable		 2w9sF-2j1dG:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 2j1d DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1
(Homo
sapiens) 		3 / 3 HIS G 749
GLU G 750
HIS G 747
 None
 0.72A 3ba0A-2j1dG:
undetectable		 3ba0A-2j1dG:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 2j1d DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1
(Homo
sapiens) 		3 / 3 GLU G 746
LEU G 743
ASP G 742
 None
 0.45A 3ko0A-2j1dG:
undetectable		 3ko0A-2j1dG:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 2j1d DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1
(Homo
sapiens) 		3 / 3 GLU G 746
LEU G 743
ASP G 742
 None
 0.40A 3ko0T-2j1dG:
undetectable		 3ko0T-2j1dG:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 2j1d DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1
(Homo
sapiens) 		4 / 6 PHE G 979
ASN G 841
ALA G 844
THR G 855
 None
 1.01A 4ejgD-2j1dG:
undetectable		 4ejgD-2j1dG:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 2j1d DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1
(Homo
sapiens) 		5 / 10 LEU G 874
LEU G 813
SER G 838
LEU G 840
LEU G 860
 None
 1.07A 4yiaA-2j1dG:
undetectable		 4yiaA-2j1dG:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 2j1d DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1
(Homo
sapiens) 		4 / 5 PHE G 960
PHE G 973
PHE G 972
VAL G 804
 None
 0.96A 5a1rA-2j1dG:
undetectable		 5a1rA-2j1dG:
23.08