SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j1u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2j1u FUCOLECTIN-RELATED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 ARG A 127
LEU A  67
VAL A  76
VAL A  39
 None
 1.03A 2bdmA-2j1uA:
undetectable		 2bdmA-2j1uA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 2j1u FUCOLECTIN-RELATED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 9 ASP A  71
GLY A  74
LEU A  75
VAL A  94
ILE A 129
 None
 1.17A 3em4B-2j1uA:
undetectable		 3em4B-2j1uA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 2j1u FUCOLECTIN-RELATED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 ASP A  71
GLY A  74
LEU A  75
VAL A  94
ILE A 129
 None
 0.97A 3em4V-2j1uA:
undetectable		 3em4V-2j1uA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 2j1u FUCOLECTIN-RELATED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 ILE A 129
LEU A  67
GLY A 125
LYS A 124
 None
 0.96A 4z69A-2j1uA:
undetectable		 4z69A-2j1uA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 2j1u FUCOLECTIN-RELATED
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 GLU A 146
ARG A  43
TYR A  79
 None
 0.47A 5trqB-2j1uA:
undetectable		 5trqB-2j1uA:
20.68