SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j23'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FKB_A_RAPA108_1 (FK506 BINDING PROTEIN)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 12	PHE A 80 GLN A 67 GLU A 68 VAL A 69 ILE A 71	None	1.17A	1fkbA-2j23A: undetectable	1fkbA-2j23A: 24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_A_TRPA1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 10	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.21A	3fhjA-2j23A: undetectable	3fhjA-2j23A: 16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_B_TRPB1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 10	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.21A	3fhjB-2j23A: undetectable	3fhjB-2j23A: 16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_C_TRPC1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 10	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.21A	3fhjC-2j23A: undetectable	3fhjC-2j23A: 16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_D_TRPD1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 9	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.20A	3fhjD-2j23A: undetectable	3fhjD-2j23A: 16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_E_TRPE1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 10	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.21A	3fhjE-2j23A: undetectable	3fhjE-2j23A: 16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FHJ_F_TRPF1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 9	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.20A	3fhjF-2j23A: undetectable	3fhjF-2j23A: 16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_A_TRPA1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 9	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.21A	3fi0A-2j23A: undetectable	3fi0A-2j23A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_F_TRPF1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 9	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.16A	3fi0F-2j23A: undetectable	3fi0F-2j23A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_H_TRPH1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 9	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.18A	3fi0H-2j23A: undetectable	3fi0H-2j23A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_I_TRPI1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 8	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.22A	3fi0I-2j23A: undetectable	3fi0I-2j23A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_J_TRPJ1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 9	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.19A	3fi0J-2j23A: undetectable	3fi0J-2j23A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_K_TRPK1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 9	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.24A	3fi0K-2j23A: undetectable	3fi0K-2j23A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_L_TRPL1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 9	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.17A	3fi0L-2j23A: undetectable	3fi0L-2j23A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_N_TRPN1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 9	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.18A	3fi0N-2j23A: undetectable	3fi0N-2j23A: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_R_TRPR1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	2j23	THIOREDOXIN (Malassezia sympodialis)	5 / 9	VAL A 89 ASP A 87 ILE A 86 VAL A 20 VAL A 52	None	1.13A	3fi0R-2j23A: undetectable	3fi0R-2j23A: 17.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FKB_A_RAPA108_1","FK506 BINDING PROTEIN","2j23","THIOREDOXIN","Malassezia sympodialis",5,"PHE A  80;GLN A  67;GLU A  68;VAL A  69;ILE A  71","None","1.17A","1fkbA-2j23A:undetectable","1fkbA-2j23A:24.11"],["3FHJ_A_TRPA1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.21A","3fhjA-2j23A:undetectable","3fhjA-2j23A:16.92"],["3FHJ_B_TRPB1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.21A","3fhjB-2j23A:undetectable","3fhjB-2j23A:16.92"],["3FHJ_C_TRPC1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.21A","3fhjC-2j23A:undetectable","3fhjC-2j23A:16.92"],["3FHJ_D_TRPD1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.20A","3fhjD-2j23A:undetectable","3fhjD-2j23A:16.92"],["3FHJ_E_TRPE1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.21A","3fhjE-2j23A:undetectable","3fhjE-2j23A:16.92"],["3FHJ_F_TRPF1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.20A","3fhjF-2j23A:undetectable","3fhjF-2j23A:16.92"],["3FI0_A_TRPA1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.21A","3fi0A-2j23A:undetectable","3fi0A-2j23A:17.59"],["3FI0_F_TRPF1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.16A","3fi0F-2j23A:undetectable","3fi0F-2j23A:17.59"],["3FI0_H_TRPH1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.18A","3fi0H-2j23A:undetectable","3fi0H-2j23A:17.59"],["3FI0_I_TRPI1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.22A","3fi0I-2j23A:undetectable","3fi0I-2j23A:undetectable"],["3FI0_J_TRPJ1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.19A","3fi0J-2j23A:undetectable","3fi0J-2j23A:17.59"],["3FI0_K_TRPK1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.24A","3fi0K-2j23A:undetectable","3fi0K-2j23A:17.59"],["3FI0_L_TRPL1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.17A","3fi0L-2j23A:undetectable","3fi0L-2j23A:17.59"],["3FI0_N_TRPN1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.18A","3fi0N-2j23A:undetectable","3fi0N-2j23A:17.59"],["3FI0_R_TRPR1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","2j23","THIOREDOXIN","Malassezia sympodialis",5,"VAL A  89;ASP A  87;ILE A  86;VAL A  20;VAL A  52","None","1.13A","3fi0R-2j23A:undetectable","3fi0R-2j23A:17.59"]]