SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j3e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 2j3e T7I23.11 PROTEIN
(Arabidopsis
thaliana) 		5 / 10 LEU A 158
ILE A 202
LEU A 155
ASP A 180
LEU A 183
 None
 1.06A 1yi4A-2j3eA:
undetectable		 1yi4A-2j3eA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 2j3e T7I23.11 PROTEIN
(Arabidopsis
thaliana) 		5 / 9 LEU A  56
ALA A 207
TYR A 206
LEU A 223
LEU A 156
 None
 1.30A 2azqA-2j3eA:
undetectable		 2azqA-2j3eA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 2j3e T7I23.11 PROTEIN
(Arabidopsis
thaliana) 		5 / 12 SER A  36
PHE A  26
THR A  38
VAL A  39
LEU A 155
 None
 1.43A 2fj1A-2j3eA:
undetectable		 2fj1A-2j3eA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 2j3e T7I23.11 PROTEIN
(Arabidopsis
thaliana) 		5 / 12 PRO A  15
ALA A  16
ALA A 207
THR A  52
LEU A  56
 None
 1.24A 2x2nB-2j3eA:
undetectable		 2x2nB-2j3eA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2j3e T7I23.11 PROTEIN
(Arabidopsis
thaliana) 		3 / 3 TRP A 229
VAL A 119
ARG A 245
 None
 0.93A 3b0wA-2j3eA:
undetectable		 3b0wA-2j3eA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2j3e T7I23.11 PROTEIN
(Arabidopsis
thaliana) 		5 / 8 ILE A  86
PHE A  26
SER A  55
LEU A 121
VAL A  53
 None
 1.39A 3ua5A-2j3eA:
undetectable		 3ua5A-2j3eA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 2j3e T7I23.11 PROTEIN
(Arabidopsis
thaliana) 		4 / 4 ILE A  89
ASN A  87
ILE A  57
VAL A  53
 None
 1.27A 4uy87-2j3eA:
undetectable		 4uy87-2j3eA:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 2j3e T7I23.11 PROTEIN
(Arabidopsis
thaliana) 		4 / 8 SER A  51
GLY A  48
ALA A  69
GLY A  45
 GDP  A1251 (-3.0A)
GDP  A1251 (-2.8A)
None
GDP  A1251 ( 4.5A)
 0.91A 5albL-2j3eA:
undetectable		 5albL-2j3eA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 2j3e T7I23.11 PROTEIN
(Arabidopsis
thaliana) 		4 / 7 VAL A  53
ASN A  54
ILE A  57
VAL A  77
 None
 0.77A 5bmvC-2j3eA:
4.1		 5bmvC-2j3eA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 2j3e T7I23.11 PROTEIN
(Arabidopsis
thaliana) 		5 / 12 LEU A 233
ILE A  86
VAL A  53
LEU A  56
ILE A  57
 None
 0.98A 6ecxA-2j3eA:
undetectable		 6ecxA-2j3eA:
22.29