SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j3t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 5 GLU C  75
TYR C  74
TYR C  73
PRO C  77
 None
 1.22A 1dfoB-2j3tC:
undetectable		 1dfoB-2j3tC:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 5 GLU C  75
TYR C  74
TYR C  73
PRO C  77
 None
 1.22A 1dfoD-2j3tC:
undetectable		 1dfoD-2j3tC:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4
(Homo
sapiens;
Mus
musculus) 		4 / 8 LEU D 158
LEU D 144
LEU C  71
THR C  66
 None
 0.91A 1dvtA-2j3tD:
undetectable
1dvtB-2j3tD:
undetectable		 1dvtA-2j3tD:
22.71
1dvtB-2j3tD:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		5 / 12 GLN B  46
GLY B  41
GLY B  39
CYH B 124
LEU B 126
 None
 1.09A 1rjdA-2j3tB:
undetectable		 1rjdA-2j3tB:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4
(Homo
sapiens;
Mus
musculus) 		5 / 12 LEU C  88
SER D 132
SER D 131
LEU D 170
HIS D 145
 None
 1.50A 1rk3A-2j3tC:
undetectable		 1rk3A-2j3tC:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		5 / 12 GLY B  39
GLY B  41
GLY B 125
GLU B  38
ASP B  22
 None
 1.16A 1xdsB-2j3tB:
undetectable		 1xdsB-2j3tB:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4
(Homo
sapiens) 		5 / 12 GLN D 163
LEU D 206
ALA D 159
LEU D 158
SER D   5
 None
 1.25A 2c12C-2j3tD:
undetectable		 2c12C-2j3tD:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 8 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.96A 2eilP-2j3tC:
undetectable
2eilW-2j3tC:
undetectable		 2eilP-2j3tC:
20.75
2eilW-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 6 GLU C  75
TYR C  74
TYR C  73
PRO C  77
 None
 1.21A 2vmyA-2j3tC:
undetectable		 2vmyA-2j3tC:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4
(Homo
sapiens) 		3 / 3 PHE D 119
TYR D 147
LEU D 111
 None
 0.49A 3keeB-2j3tD:
undetectable		 3keeB-2j3tD:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 6 PHE C  61
PHE C  64
HIS C  72
VAL C  83
 None
 0.95A 3lb3A-2j3tC:
undetectable		 3lb3A-2j3tC:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 6 PHE C  61
PHE C  64
HIS C  72
VAL C  83
 None
 0.95A 3lb3B-2j3tC:
undetectable		 3lb3B-2j3tC:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4
(Homo
sapiens) 		3 / 3 PHE D 119
TYR D 147
LEU D 111
 None
 0.56A 3sueB-2j3tD:
undetectable		 3sueB-2j3tD:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4
(Homo
sapiens;
Mus
musculus) 		5 / 12 LEU C  88
SER D 132
SER D 131
LEU D 170
HIS D 145
 None
 1.49A 3vt7A-2j3tC:
undetectable		 3vt7A-2j3tC:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		3 / 3 PHE C 108
VAL C  82
ILE C  80
 None
 0.50A 4emaA-2j3tC:
undetectable		 4emaA-2j3tC:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		5 / 12 GLU C  34
GLY C  28
TYR C  69
VAL C  83
TYR C   7
 None
 1.42A 4ffwA-2j3tC:
undetectable		 4ffwA-2j3tC:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		5 / 12 LEU C  42
GLY C  60
ILE C  45
LYS C  58
LEU C  62
 None
 1.03A 4gc9A-2j3tC:
undetectable		 4gc9A-2j3tC:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		4 / 7 GLU B  61
GLU B  62
TYR B  93
LEU B  85
 None
 1.15A 4twdF-2j3tB:
undetectable
4twdJ-2j3tB:
undetectable		 4twdF-2j3tB:
21.17
4twdJ-2j3tB:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 7 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.89A 5b1aC-2j3tC:
undetectable
5b1aJ-2j3tC:
undetectable		 5b1aC-2j3tC:
20.75
5b1aJ-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 7 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.89A 5b1aP-2j3tC:
undetectable
5b1aW-2j3tC:
undetectable		 5b1aP-2j3tC:
20.75
5b1aW-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 7 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.88A 5b3sC-2j3tC:
undetectable
5b3sJ-2j3tC:
undetectable		 5b3sC-2j3tC:
20.75
5b3sJ-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 7 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.88A 5b3sP-2j3tC:
undetectable		 5b3sP-2j3tC:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		5 / 8 ILE C  80
ALA C 103
VAL C 106
VAL C  82
HIS C  99
 None
 1.49A 5ecnD-2j3tC:
undetectable		 5ecnD-2j3tC:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 7 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.95A 5iy5C-2j3tC:
undetectable
5iy5J-2j3tC:
undetectable		 5iy5C-2j3tC:
21.34
5iy5J-2j3tC:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		5 / 12 VAL B  15
LEU B  10
PHE B   7
ARG B  43
LEU B 126
 None
 1.24A 5nd4B-2j3tB:
undetectable		 5nd4B-2j3tB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4
(Homo
sapiens) 		3 / 3 GLU D  81
ARG D  74
TYR D  75
 None
 0.65A 5trqB-2j3tD:
undetectable		 5trqB-2j3tD:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		5 / 12 LEU B 131
ILE B 136
GLY B 135
LEU B  69
VAL B  65
 None
 0.98A 5twjA-2j3tB:
undetectable		 5twjA-2j3tB:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		5 / 10 LEU B 131
ILE B 136
GLY B 135
LEU B  69
VAL B  65
 None
 0.98A 5twjB-2j3tB:
undetectable		 5twjB-2j3tB:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		5 / 12 LEU B 131
ILE B 136
GLY B 135
LEU B  69
VAL B  65
 None
 0.96A 5twjC-2j3tB:
undetectable		 5twjC-2j3tB:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		5 / 11 LEU B 131
ILE B 136
GLY B 135
LEU B  69
VAL B  65
 None
 0.95A 5twjD-2j3tB:
undetectable		 5twjD-2j3tB:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4
(Homo
sapiens;
Mus
musculus) 		4 / 8 ARG C  23
PHE C  64
THR C  86
GLY D 122
 None
 1.01A 5v0vA-2j3tC:
2.0		 5v0vA-2j3tC:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4
(Homo
sapiens;
Mus
musculus) 		5 / 12 SER D   5
LEU D 158
PHE C  48
ILE D  16
GLY D  14
 None
 1.06A 5veuB-2j3tD:
undetectable		 5veuB-2j3tD:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 7 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.93A 5z84C-2j3tC:
undetectable
5z84J-2j3tC:
undetectable		 5z84C-2j3tC:
20.75
5z84J-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 6 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.89A 5z84P-2j3tC:
undetectable
5z84W-2j3tC:
undetectable		 5z84P-2j3tC:
20.75
5z84W-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 6 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.86A 5z85P-2j3tC:
undetectable
5z85W-2j3tC:
undetectable		 5z85P-2j3tC:
20.75
5z85W-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 6 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.92A 5z86C-2j3tC:
undetectable
5z86J-2j3tC:
undetectable		 5z86C-2j3tC:
20.75
5z86J-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 6 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.88A 5z86P-2j3tC:
undetectable
5z86W-2j3tC:
undetectable		 5z86P-2j3tC:
20.75
5z86W-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 6 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.90A 5zcoP-2j3tC:
undetectable
5zcoW-2j3tC:
undetectable		 5zcoP-2j3tC:
20.75
5zcoW-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 6 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.94A 5zcpC-2j3tC:
undetectable
5zcpJ-2j3tC:
undetectable		 5zcpC-2j3tC:
20.75
5zcpJ-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		4 / 6 ARG C  94
GLN C  65
PHE C  64
PHE C  61
 None
 0.92A 5zcpP-2j3tC:
undetectable
5zcpW-2j3tC:
undetectable		 5zcpP-2j3tC:
20.75
5zcpW-2j3tC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
(Mus
musculus) 		3 / 3 ASN C   5
VAL C  90
HIS C  72
 None
 0.88A 6a5yD-2j3tC:
undetectable		 6a5yD-2j3tC:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		6 / 12 LEU B  48
GLY B 129
GLY B  45
SER B 138
LEU B 134
ILE B 136
 None
 1.49A 6ectA-2j3tB:
undetectable		 6ectA-2j3tB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		6 / 12 LEU B  48
GLY B 129
SER B 138
GLU B  50
LEU B 134
ILE B 136
 None
 1.36A 6ectA-2j3tB:
undetectable		 6ectA-2j3tB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		6 / 12 LEU B  48
GLY B 129
SER B 138
GLU B  50
LEU B 134
ILE B 136
 None
 1.38A 6ecxA-2j3tB:
undetectable		 6ecxA-2j3tB:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		3 / 3 LEU B  37
GLY B  41
PHE B  78
 None
 0.59A 6exiC-2j3tB:
undetectable		 6exiC-2j3tB:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		3 / 3 LEU B 103
SER B  99
PHE B 100
 None
 0.50A 6fgcA-2j3tB:
undetectable		 6fgcA-2j3tB:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A
(Homo
sapiens) 		3 / 3 PHE B  42
ARG B  43
GLN B  46
 None
 0.92A 6g1pB-2j3tB:
undetectable		 6g1pB-2j3tB:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4
(Mus
musculus;
Homo
sapiens) 		5 / 8 PHE D 142
PHE C  48
VAL D 156
SER D   5
TYR D   7
 None
 1.14A 6huoC-2j3tD:
undetectable
6huoD-2j3tD:
undetectable		 6huoC-2j3tD:
16.13
6huoD-2j3tD:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_D_DZPD2001_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 1
TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 4
(Mus
musculus;
Homo
sapiens) 		5 / 9 PHE D 142
PHE C  48
VAL D 156
SER D   5
TYR D   7
 None
 1.13A 6hupC-2j3tD:
1.5
6hupD-2j3tD:
0.8		 6hupC-2j3tD:
16.13
6hupD-2j3tD:
15.28