SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j3w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 2j3w ZGC 92866
(Danio
rerio) 		4 / 7 ASP B 111
ASP B 112
TYR B 116
TYR B 115
 None
 1.48A 1ceaB-2j3wB:
undetectable		 1ceaB-2j3wB:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 2j3w ZGC 92866
(Danio
rerio) 		4 / 8 PHE B  98
PHE B  33
ALA B 141
LEU B 170
 None
 1.08A 1x8vA-2j3wB:
undetectable		 1x8vA-2j3wB:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2j3w ZGC 92866
(Danio
rerio) 		5 / 12 ALA B 141
ALA B 140
LEU B 123
ILE B 124
LEU B  54
 None
 0.98A 2aclG-2j3wB:
undetectable		 2aclG-2j3wB:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 2j3w ZGC 92866
(Danio
rerio) 		5 / 9 GLY B 144
THR B 143
ALA B 140
LEU B 137
THR B 168
 None
 1.26A 2npnA-2j3wB:
undetectable		 2npnA-2j3wB:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 2j3w ZGC 92866
(Danio
rerio) 		5 / 9 LEU B  86
VAL B  93
ILE B 146
GLY B 144
ILE B  89
 None
 1.08A 3ekqB-2j3wB:
undetectable		 3ekqB-2j3wB:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 2j3w ZGC 92866
(Danio
rerio) 		5 / 12 LEU B  66
GLY B 155
VAL B 147
ILE B 172
ILE B 150
 None
 0.92A 3tkgD-2j3wB:
undetectable		 3tkgD-2j3wB:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2j3w ZGC 92866
(Danio
rerio) 		5 / 12 ALA B 141
ALA B 140
LEU B 123
ILE B 124
LEU B  54
 None
 1.07A 4k6iA-2j3wB:
undetectable		 4k6iA-2j3wB:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2j3w ZGC 92866
(Danio
rerio) 		3 / 3 ILE B  85
ASP B 182
ARG B  78
 None
 0.82A 4pstA-2j3wB:
undetectable		 4pstA-2j3wB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2j3w ZGC 92866
(Danio
rerio) 		4 / 4 ILE B  89
GLY B 144
ILE B 150
LEU B 170
 None
 0.89A 5dzkl-2j3wB:
undetectable
5dzkz-2j3wB:
undetectable		 5dzkl-2j3wB:
24.19
5dzkz-2j3wB:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 2j3w ZGC 92866
(Danio
rerio) 		5 / 9 LEU B  86
VAL B  93
ILE B 146
GLY B 144
ILE B  89
 None
 1.06A 5kqxB-2j3wB:
undetectable		 5kqxB-2j3wB:
20.21