SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j3z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		3 / 3 GLU A  69
ILE A  68
ARG A  86
 None
SO4  A1437 (-3.7A)
SO4  A1437 (-2.8A)
 0.82A 1cd2A-2j3zA:
undetectable		 1cd2A-2j3zA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 8 GLN A 134
GLU A 127
ASP A 130
ARG A 133
 None
 1.09A 1dtlA-2j3zA:
undetectable		 1dtlA-2j3zA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 6 ALA A 297
SER A 345
LEU A 351
TRP A 229
 None
 1.05A 1gahA-2j3zA:
undetectable		 1gahA-2j3zA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		5 / 11 LEU A 308
LYS A 335
LYS A 339
ILE A 341
VAL A 301
 None
 1.43A 1gx9A-2j3zA:
undetectable		 1gx9A-2j3zA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 8 ALA A 373
GLU A 218
ALA A 297
THR A 349
 None
 0.82A 1ie4B-2j3zA:
undetectable
1ie4D-2j3zA:
undetectable		 1ie4B-2j3zA:
14.25
1ie4D-2j3zA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 TYR A 174
VAL A  41
GLU A  25
LEU A 151
 None
 1.01A 1j96B-2j3zA:
undetectable		 1j96B-2j3zA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 6 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 1.05A 1v54A-2j3zA:
undetectable
1v54J-2j3zA:
undetectable		 1v54A-2j3zA:
19.36
1v54J-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.97A 1v54N-2j3zA:
undetectable
1v54W-2j3zA:
undetectable		 1v54N-2j3zA:
19.36
1v54W-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		3 / 3 ASP A 422
ILE A 193
VAL A 132
 None
 0.65A 2avvD-2j3zA:
undetectable		 2avvD-2j3zA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 ARG A 299
SER A 348
PHE A 358
GLU A 389
 SO4  A1438 (-3.3A)
GOL  A1435 ( 3.0A)
GOL  A1434 ( 4.3A)
GOL  A1435 (-3.4A)
 1.18A 2c8aA-2j3zA:
20.8		 2c8aA-2j3zA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 6 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 1.03A 2dysN-2j3zA:
undetectable
2dysW-2j3zA:
undetectable		 2dysN-2j3zA:
19.36
2dysW-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 6 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 1.07A 2eijA-2j3zA:
undetectable
2eijJ-2j3zA:
undetectable		 2eijA-2j3zA:
19.36
2eijJ-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 1.03A 2eikA-2j3zA:
undetectable
2eikJ-2j3zA:
undetectable		 2eikA-2j3zA:
19.36
2eikJ-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 6 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 1.01A 2eilA-2j3zA:
0.0
2eilJ-2j3zA:
undetectable		 2eilA-2j3zA:
19.36
2eilJ-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		5 / 11 LEU A  61
LEU A  90
ILE A  68
VAL A  82
ILE A  85
 None
None
SO4  A1437 (-3.7A)
None
None
 1.08A 2uxoB-2j3zA:
undetectable		 2uxoB-2j3zA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 6 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 1.11A 2zxwA-2j3zA:
undetectable
2zxwJ-2j3zA:
undetectable		 2zxwA-2j3zA:
19.36
2zxwJ-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 8 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.89A 3abkA-2j3zA:
undetectable
3abkJ-2j3zA:
undetectable		 3abkA-2j3zA:
19.36
3abkJ-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		3 / 3 SER A 216
GLN A 217
PHE A 191
 None
None
SO4  A1439 (-4.8A)
 0.85A 3g4lC-2j3zA:
undetectable		 3g4lC-2j3zA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 5 GLN A 293
THR A 294
GLU A 140
THR A 142
 None
 1.42A 3glqA-2j3zA:
undetectable		 3glqA-2j3zA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		5 / 8 GLU A 389
LEU A 391
TYR A 237
PHE A 381
LEU A 253
 GOL  A1435 (-3.4A)
GOL  A1435 ( 4.9A)
None
None
GOL  A1435 (-4.5A)
 1.43A 3i45A-2j3zA:
undetectable		 3i45A-2j3zA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		5 / 8 GLU A 218
ARG A 366
ARG A 368
ASP A 422
PHE A 401
 None
 1.44A 3mjrD-2j3zA:
undetectable		 3mjrD-2j3zA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		3 / 3 ASN A 271
ASP A 273
ASN A 276
 None
 0.68A 4agaA-2j3zA:
undetectable		 4agaA-2j3zA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 8 LEU A 246
SER A 242
ASP A 236
TYR A 237
 None
 1.06A 4drjB-2j3zA:
undetectable		 4drjB-2j3zA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 8 PRO A 161
VAL A 162
PRO A 195
ILE A 111
 CO  A1432 ( 4.7A)
None
None
None
 0.95A 4iilA-2j3zA:
undetectable		 4iilA-2j3zA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		3 / 3 ASP A  54
TRP A  29
SER A 148
 None
 0.76A 4lrhB-2j3zA:
undetectable		 4lrhB-2j3zA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		3 / 3 ASP A  54
TRP A  29
SER A 148
 None
 0.77A 4lrhF-2j3zA:
undetectable		 4lrhF-2j3zA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 6 TYR A 141
THR A 337
GLN A 135
LEU A 109
 None
 1.44A 4qzuC-2j3zA:
undetectable		 4qzuC-2j3zA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 TYR A 257
ARG A 299
SER A 348
GLU A 389
 GOL  A1435 (-3.4A)
SO4  A1438 (-3.3A)
GOL  A1435 ( 3.0A)
GOL  A1435 (-3.4A)
 0.81A 4xzkA-2j3zA:
12.4		 4xzkA-2j3zA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.96A 5b1aA-2j3zA:
undetectable
5b1aJ-2j3zA:
undetectable		 5b1aA-2j3zA:
19.36
5b1aJ-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.93A 5b1bA-2j3zA:
undetectable
5b1bJ-2j3zA:
undetectable		 5b1bA-2j3zA:
19.36
5b1bJ-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.93A 5b3sA-2j3zA:
undetectable
5b3sJ-2j3zA:
undetectable		 5b3sA-2j3zA:
19.36
5b3sJ-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 6 SER A 287
GLY A 251
ASP A 256
GLY A 247
 None
 0.93A 5cdnC-2j3zA:
undetectable
5cdnD-2j3zA:
undetectable		 5cdnC-2j3zA:
21.70
5cdnD-2j3zA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		6 / 12 ILE A 260
ALA A 248
LEU A 286
PHE A 346
ILE A 431
ILE A 279
 None
 1.45A 5e8qA-2j3zA:
undetectable		 5e8qA-2j3zA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		6 / 12 ILE A 260
ALA A 248
LEU A 286
PHE A 346
ILE A 431
ILE A 279
 None
 1.46A 5eajA-2j3zA:
undetectable		 5eajA-2j3zA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		3 / 3 ASP A 220
SER A 353
TYR A 298
 None
 0.86A 5glmA-2j3zA:
undetectable		 5glmA-2j3zA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.94A 5iy5A-2j3zA:
undetectable
5iy5J-2j3zA:
undetectable		 5iy5A-2j3zA:
19.36
5iy5J-2j3zA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		3 / 3 ARG A 368
PHE A 377
LEU A 392
 None
 0.85A 5veuA-2j3zA:
undetectable		 5veuA-2j3zA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 1.00A 5xdqA-2j3zA:
undetectable
5xdqJ-2j3zA:
undetectable		 5xdqA-2j3zA:
19.36
5xdqJ-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.90A 5xdqN-2j3zA:
undetectable
5xdqW-2j3zA:
undetectable		 5xdqN-2j3zA:
19.36
5xdqW-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 8 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.91A 5xdxN-2j3zA:
undetectable
5xdxW-2j3zA:
undetectable		 5xdxN-2j3zA:
19.36
5xdxW-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 8 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.92A 5zcoA-2j3zA:
undetectable
5zcoJ-2j3zA:
undetectable		 5zcoA-2j3zA:
19.36
5zcoJ-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 7 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.90A 5zcpA-2j3zA:
undetectable
5zcpJ-2j3zA:
undetectable		 5zcpA-2j3zA:
19.36
5zcpJ-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 8 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.92A 5zcpN-2j3zA:
undetectable
5zcpW-2j3zA:
undetectable		 5zcpN-2j3zA:
19.36
5zcpW-2j3zA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2j3z C2 TOXIN COMPONENT I
(Clostridium
botulinum) 		4 / 8 LEU A  89
ARG A  28
THR A  31
LEU A  33
 None
 0.94A 5zcqN-2j3zA:
undetectable
5zcqW-2j3zA:
undetectable		 5zcqN-2j3zA:
19.36
5zcqW-2j3zA:
12.62