SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j4t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DY5_A_ACTA600_0
(RIBONUCLEASE A)		 2j4t ANGIOGENIN-4
(Mus
musculus) 		4 / 4 HIS A  12
VAL A  41
ASN A  42
THR A  43
 None
 0.47A 1dy5A-2j4tA:
17.0		 1dy5A-2j4tA:
31.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 2j4t ANGIOGENIN-4
(Mus
musculus) 		4 / 7 ARG A  32
ALA A  94
ILE A  76
PRO A  17
 None
 0.88A 2fxdB-2j4tA:
undetectable		 2fxdB-2j4tA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 2j4t ANGIOGENIN-4
(Mus
musculus) 		5 / 12 ILE A  69
VAL A 102
ILE A 103
ASN A  51
ILE A  55
 None
 0.99A 3kpdC-2j4tA:
undetectable		 3kpdC-2j4tA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 2j4t ANGIOGENIN-4
(Mus
musculus) 		3 / 3 GLU A 106
HIS A 112
VAL A 111
 None
 0.91A 5trqB-2j4tA:
undetectable		 5trqB-2j4tA:
17.84