SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j64'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 2j64 FICOLIN-3
(Homo
sapiens) 		4 / 6 ARG A  58
GLY A 173
TYR A 177
TRP A 175
 None
 1.28A 1kf6M-2j64A:
undetectable
1kf6N-2j64A:
undetectable		 1kf6M-2j64A:
19.39
1kf6N-2j64A:
20.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J1G_F_SC2F1290_1
(FICOLIN-2)		 2j64 FICOLIN-3
(Homo
sapiens) 		5 / 10 SER A  26
ASP A  44
ASP A  46
THR A  47
ARG A  57
 None
 0.98A 2j1gE-2j64A:
36.1
2j1gF-2j64A:
36.0		 2j1gE-2j64A:
51.38
2j1gF-2j64A:
51.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 2j64 FICOLIN-3
(Homo
sapiens) 		4 / 7 PHE A  65
GLY A 187
GLY A  61
PHE A 153
 None
 0.97A 3ko0M-2j64A:
undetectable
3ko0P-2j64A:
undetectable		 3ko0M-2j64A:
18.26
3ko0P-2j64A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_A_URFA521_1
(RNA DEPENDENT RNA
POLYMERASE)		 2j64 FICOLIN-3
(Homo
sapiens) 		4 / 5 ARG A 112
ASP A  46
ASP A  44
ARG A 102
 None
 1.47A 3naiA-2j64A:
undetectable		 3naiA-2j64A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2j64 FICOLIN-3
(Homo
sapiens) 		4 / 6 HIS A 172
ILE A 170
TYR A 177
TYR A  72
 None
 1.06A 5ih0A-2j64A:
undetectable		 5ih0A-2j64A:
20.27