SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2j67 TOLL LIKE RECEPTOR
10
(Homo
sapiens) 		5 / 12 LEU A 656
LYS A 691
VAL A 695
ILE A 728
ILE A 726
 None
 1.02A 1epbB-2j67A:
undetectable		 1epbB-2j67A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 2j67 TOLL LIKE RECEPTOR
10
(Homo
sapiens) 		3 / 3 TRP A 757
PHE A 767
TRP A 768
 None
 1.15A 1r15C-2j67A:
undetectable		 1r15C-2j67A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 2j67 TOLL LIKE RECEPTOR
10
(Homo
sapiens) 		3 / 3 TRP A 757
PHE A 767
TRP A 768
 None
 1.14A 1r15F-2j67A:
2.3		 1r15F-2j67A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 2j67 TOLL LIKE RECEPTOR
10
(Homo
sapiens) 		3 / 3 TRP A 757
PHE A 767
TRP A 768
 None
 1.15A 1r15G-2j67A:
2.3		 1r15G-2j67A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 2j67 TOLL LIKE RECEPTOR
10
(Homo
sapiens) 		3 / 3 TRP A 757
PHE A 767
TRP A 768
 None
 1.15A 1r15H-2j67A:
undetectable		 1r15H-2j67A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 2j67 TOLL LIKE RECEPTOR
10
(Homo
sapiens) 		4 / 4 ASP A 644
LEU A 729
LEU A 696
LEU A 730
 None
 1.28A 1u18A-2j67A:
undetectable		 1u18A-2j67A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2j67 TOLL LIKE RECEPTOR
10
(Homo
sapiens) 		3 / 3 ILE A 638
ASP A 644
PHE A 700
 None
 0.66A 1uwjB-2j67A:
undetectable		 1uwjB-2j67A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 2j67 TOLL LIKE RECEPTOR
10
(Homo
sapiens) 		5 / 12 LEU A 749
SER A 697
LEU A 696
VAL A 695
ASP A 644
 None
 0.99A 2c12C-2j67A:
undetectable		 2c12C-2j67A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 2j67 TOLL LIKE RECEPTOR
10
(Homo
sapiens) 		3 / 3 TYR A 668
TYR A 708
ILE A 682
 None
 0.67A 3eteA-2j67A:
undetectable
3eteB-2j67A:
undetectable		 3eteA-2j67A:
18.40
3eteB-2j67A:
18.40