SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j76'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XF1_A_ACTA1107_0 (C5A PEPTIDASE)	2j76	EUKARYOTIC TRANSLATION INITIATION FACTOR 4B (Homo sapiens)	4 / 5	LEU E 5 GLY E 45 ILE E 17 PHE E 49	None	0.81A	1xf1A-2j76E: undetectable	1xf1A-2j76E: 7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XF1_B_ACTB1108_0 (C5A PEPTIDASE)	2j76	EUKARYOTIC TRANSLATION INITIATION FACTOR 4B (Homo sapiens)	4 / 6	LEU E 5 GLY E 45 ILE E 17 PHE E 49	None	0.83A	1xf1B-2j76E: undetectable	1xf1B-2j76E: 7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y4L_B_SVRB301_1 (PHOSPHOLIPASE A2 HOMOLOG 2)	2j76	EUKARYOTIC TRANSLATION INITIATION FACTOR 4B (Homo sapiens)	5 / 12	GLY E 43 LEU E 5 GLY E 45 ARG E 30 PRO E 35	None	1.26A	1y4lA-2j76E: undetectable	1y4lA-2j76E: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ND7_B_TA1B601_2 (TUBULIN BETA-2B CHAIN)	2j76	EUKARYOTIC TRANSLATION INITIATION FACTOR 4B (Homo sapiens)	3 / 3	THR E 2 PRO E 32 ARG E 33	None	0.87A	5nd7B-2j76E: undetectable	5nd7B-2j76E: 13.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XF1_A_ACTA1107_0","C5A PEPTIDASE","2j76","EUKARYOTIC TRANSLATION INITIATION FACTOR 4B","Homo sapiens",4,"LEU E   5;GLY E  45;ILE E  17;PHE E  49","None","0.81A","1xf1A-2j76E:undetectable","1xf1A-2j76E:7.63"],["1XF1_B_ACTB1108_0","C5A PEPTIDASE","2j76","EUKARYOTIC TRANSLATION INITIATION FACTOR 4B","Homo sapiens",4,"LEU E   5;GLY E  45;ILE E  17;PHE E  49","None","0.83A","1xf1B-2j76E:undetectable","1xf1B-2j76E:7.63"],["1Y4L_B_SVRB301_1","PHOSPHOLIPASE A2 HOMOLOG 2;PHOSPHOLIPASE A2 HOMOLOG 2","2j76","EUKARYOTIC TRANSLATION INITIATION FACTOR 4B","Homo sapiens",5,"GLY E  43;LEU E   5;GLY E  45;ARG E  30;PRO E  35","None","1.26A","1y4lA-2j76E:undetectable","1y4lA-2j76E:20.33"],["5ND7_B_TA1B601_2","TUBULIN BETA-2B CHAIN","2j76","EUKARYOTIC TRANSLATION INITIATION FACTOR 4B","Homo sapiens",3,"THR E   2;PRO E  32;ARG E  33","None","0.87A","5nd7B-2j76E:undetectable","5nd7B-2j76E:13.11"]]