SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2j7c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 TRP A 134
ALA A 181
VAL A 170
 None
 0.95A 1av2C-2j7cA:
undetectable
1av2D-2j7cA:
undetectable		 1av2C-2j7cA:
2.35
1av2D-2j7cA:
2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQU_A_EQIA329_0
(PROTEIN (ESTRADIOL
17
BETA-DEHYDROGENASE
1))		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		5 / 10 VAL A 290
LEU A 252
GLY A 291
HIS A 243
GLU A 341
 None
 1.34A 1equA-2j7cA:
2.3		 1equA-2j7cA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 7 ARG A 148
THR A 211
VAL A 212
ALA A 204
 None
 0.79A 1fo4B-2j7cA:
undetectable		 1fo4B-2j7cA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 ALA A 190
VAL A 170
TRP A 134
 None
 1.02A 1gmkA-2j7cA:
undetectable
1gmkB-2j7cA:
undetectable		 1gmkA-2j7cA:
2.35
1gmkB-2j7cA:
2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 ALA A 190
VAL A 170
TRP A 134
 None
 1.01A 1gmkC-2j7cA:
undetectable
1gmkD-2j7cA:
undetectable		 1gmkC-2j7cA:
2.35
1gmkD-2j7cA:
2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		5 / 12 SER A 436
LEU A  71
ILE A 416
ILE A 379
LEU A 375
 None
 1.20A 1kyvA-2j7cA:
undetectable
1kyvE-2j7cA:
undetectable		 1kyvA-2j7cA:
18.66
1kyvE-2j7cA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		5 / 12 ILE A 379
LEU A 375
SER A 436
LEU A  71
ILE A 416
 None
 1.19A 1kyvB-2j7cA:
undetectable
1kyvC-2j7cA:
undetectable		 1kyvB-2j7cA:
18.66
1kyvC-2j7cA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		5 / 12 ILE A 379
LEU A 375
SER A 436
LEU A  71
ILE A 416
 None
 1.18A 1kyvC-2j7cA:
undetectable
1kyvD-2j7cA:
undetectable		 1kyvC-2j7cA:
18.66
1kyvD-2j7cA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		5 / 12 ILE A 379
LEU A 375
SER A 436
LEU A  71
ILE A 416
 None
 1.19A 1kyvD-2j7cA:
undetectable
1kyvE-2j7cA:
undetectable		 1kyvD-2j7cA:
18.66
1kyvE-2j7cA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 7 TYR A 435
GLU A 351
THR A  16
VAL A  73
 None
IDE  A1446 (-2.5A)
None
None
 1.19A 1tv8A-2j7cA:
7.3		 1tv8A-2j7cA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 VAL A 170
VAL A 194
TRP A 134
 None
 0.91A 1w5uA-2j7cA:
undetectable
1w5uB-2j7cA:
undetectable		 1w5uA-2j7cA:
2.35
1w5uB-2j7cA:
2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 5 PHE A 267
LEU A 176
PHE A 241
MET A 242
 None
 1.11A 1wrkB-2j7cA:
undetectable		 1wrkB-2j7cA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 7 PHE A 267
LEU A 176
PHE A 241
MET A 242
 None
 1.18A 1wrlE-2j7cA:
undetectable		 1wrlE-2j7cA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 PHE A 221
TYR A 256
TYR A 342
 None
 1.07A 1x70B-2j7cA:
1.2		 1x70B-2j7cA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 4 ILE A 427
ASP A  64
LEU A  71
ARG A 413
 None
 1.03A 2a7qA-2j7cA:
1.4		 2a7qA-2j7cA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 8 TYR A 435
GLU A 351
THR A  16
VAL A  73
 None
IDE  A1446 (-2.5A)
None
None
 1.16A 2fb2A-2j7cA:
2.5		 2fb2A-2j7cA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 7 TYR A 435
GLU A 351
THR A  16
VAL A  73
 None
IDE  A1446 (-2.5A)
None
None
 1.16A 2fb2B-2j7cA:
3.6		 2fb2B-2j7cA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 VAL A 194
TRP A 134
VAL A 170
 None
 0.92A 2izqC-2j7cA:
undetectable
2izqD-2j7cA:
undetectable		 2izqC-2j7cA:
2.35
2izqD-2j7cA:
2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 5 ALA A 354
ASP A 402
ASP A 420
ASP A 368
 None
 1.18A 2nyuB-2j7cA:
undetectable		 2nyuB-2j7cA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 LEU A 272
TYR A 260
GLY A 258
 None
 0.62A 2ocuA-2j7cA:
undetectable		 2ocuA-2j7cA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 5 LEU A 124
PRO A 125
LEU A 128
ILE A 139
 None
 0.83A 2qd4A-2j7cA:
undetectable		 2qd4A-2j7cA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		5 / 11 ASN A 165
GLU A 166
TYR A 295
GLU A 351
TRP A 398
 IDE  A1446 (-3.1A)
IDE  A1446 (-2.5A)
IDE  A1446 (-3.5A)
IDE  A1446 (-2.5A)
IDE  A1446 (-3.6A)
 0.84A 2v3dB-2j7cA:
16.6		 2v3dB-2j7cA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 8 TYR A 433
ARG A 365
ARG A 371
HIS A 367
 None
 1.46A 2vxaA-2j7cA:
undetectable
2vxaC-2j7cA:
undetectable
2vxaE-2j7cA:
undetectable		 2vxaA-2j7cA:
10.47
2vxaC-2j7cA:
10.47
2vxaE-2j7cA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 8 HIS A 367
ARG A 371
TYR A 433
ARG A 365
 None
 1.48A 2vxaB-2j7cA:
undetectable
2vxaG-2j7cA:
undetectable
2vxaH-2j7cA:
undetectable		 2vxaB-2j7cA:
10.47
2vxaG-2j7cA:
10.47
2vxaH-2j7cA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 8 GLY A 394
GLU A 346
ILE A 386
ALA A 382
 None
 0.94A 3aodA-2j7cA:
undetectable		 3aodA-2j7cA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 5 LEU A 392
ILE A 331
ILE A 386
GLY A 394
 None
 0.85A 3bufA-2j7cA:
undetectable		 3bufA-2j7cA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 GLU A 408
GLU A 405
TRP A 324
 None
IDE  A1446 (-2.8A)
None
 1.01A 3hrdA-2j7cA:
undetectable
3hrdE-2j7cA:
undetectable
3hrdF-2j7cA:
undetectable		 3hrdA-2j7cA:
19.51
3hrdE-2j7cA:
19.51
3hrdF-2j7cA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 8 PHE A 151
VAL A 212
GLY A 215
GLY A 155
 None
 0.64A 3n9jB-2j7cA:
undetectable		 3n9jB-2j7cA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 7 GLY A  23
ASP A  52
GLY A  51
HIS A  40
 None
 0.80A 4c5nA-2j7cA:
2.2		 4c5nA-2j7cA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 8 GLY A  23
ASP A  52
GLY A  51
HIS A  40
 None
 0.76A 4c5nC-2j7cA:
2.0		 4c5nC-2j7cA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 8 MET A 280
ILE A 255
PRO A 273
VAL A 194
 None
 1.12A 4f4dB-2j7cA:
undetectable		 4f4dB-2j7cA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 4 LEU A 124
PRO A 125
LEU A 128
ILE A 139
 None
 0.90A 4f4dB-2j7cA:
undetectable		 4f4dB-2j7cA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 7 ASP A  56
GLN A 424
ASN A  59
TRP A  61
 None
ACT  A1447 ( 4.8A)
None
None
 0.94A 4ii8A-2j7cA:
undetectable		 4ii8A-2j7cA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 ASP A 123
TRP A 398
SER A  79
 None
IDE  A1446 (-3.6A)
None
 0.95A 4lrhB-2j7cA:
undetectable		 4lrhB-2j7cA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 ASP A 123
TRP A 398
SER A  79
 None
IDE  A1446 (-3.6A)
None
 1.04A 4lrhF-2j7cA:
undetectable		 4lrhF-2j7cA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		5 / 12 VAL A  14
SER A 431
ASP A 402
GLY A 432
ASP A 368
 None
 1.35A 4pevA-2j7cA:
1.4		 4pevA-2j7cA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		5 / 12 VAL A  14
SER A 431
ASP A 402
GLY A 432
ASP A 368
 None
 1.35A 4pevC-2j7cA:
undetectable		 4pevC-2j7cA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 ASN A 165
PHE A 396
TYR A  76
 IDE  A1446 (-3.1A)
None
None
 0.66A 4u15A-2j7cA:
undetectable		 4u15A-2j7cA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 7 TYR A 146
VAL A 158
ILE A 105
LEU A  98
 None
 0.89A 4xo7A-2j7cA:
11.1		 4xo7A-2j7cA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 5 ALA A 200
HIS A 243
PRO A 254
PHE A 221
 None
 1.40A 4ze2A-2j7cA:
undetectable		 4ze2A-2j7cA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 ALA A 193
ASN A 196
LEU A 197
 None
 0.52A 5i1nC-2j7cA:
undetectable		 5i1nC-2j7cA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		5 / 9 ILE A 331
PRO A 328
VAL A 438
LEU A 444
LEU A 335
 None
 1.50A 5iepA-2j7cA:
undetectable		 5iepA-2j7cA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 SER A 296
TYR A 295
TYR A 294
 None
IDE  A1446 (-3.5A)
None
 0.74A 5lakA-2j7cA:
undetectable
5lakI-2j7cA:
undetectable		 5lakA-2j7cA:
21.79
5lakI-2j7cA:
3.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		3 / 3 SER A 296
TYR A 295
TYR A 294
 None
IDE  A1446 (-3.5A)
None
 0.62A 5lakC-2j7cA:
undetectable
5lakJ-2j7cA:
undetectable		 5lakC-2j7cA:
21.79
5lakJ-2j7cA:
3.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 6 ILE A  80
ASP A  99
LEU A  98
GLY A  97
 None
 1.00A 5x5qE-2j7cA:
undetectable		 5x5qE-2j7cA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 7 VAL A  45
PRO A 125
LEU A 128
PHE A 126
 None
 0.98A 6aycA-2j7cA:
undetectable		 6aycA-2j7cA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2j7c BETA-GLUCOSIDASE A
(Thermotoga
maritima) 		4 / 5 ALA A 377
TYR A 374
GLN A 381
ILE A 331
 None
 1.36A 6f6sA-2j7cA:
undetectable
6f6sB-2j7cA:
undetectable		 6f6sA-2j7cA:
11.63
6f6sB-2j7cA:
8.33